Rchr
J-GLOBAL ID:200901034490549560
Update date: Feb. 01, 2024
Isotani Ayako
イソタニ アヤコ | Isotani Ayako
Affiliation and department:
Job title:
Graduate School Student
Research field (2):
Laboratory animal science
, Developmental biology
Research keywords (5):
Developmental Biology
, Developmental Engineering
, Experimental Animals
, 生殖生理学
, Reproductive physiology
Research theme for competitive and other funds (21):
- 2023 - 2025 胎児の臓器を立体構造を保持したまま成体内で育てる研究
- 2020 - 2025 Elucidation of the gene expression cascade responsible for male sexuality and acquisition of fertility
- 2021 - 2023 Study of recognition mechanism between mother and embryo using the xeno-hybrid placenta
- 2020 - 2023 Positional and quantitative regulation of the central nervous cells by interaction of pattern formation, proliferation and differentiation timing
- 2018 - 2020 A study of the dominance of sex differentiation in the sex chimeric rat model
- 2018 - 2020 A novel treatment of allergy by mucosal barrier enhancement through selective IgA class switching
- 2016 - 2019 Development of a new treatment model for placental dysfunction
- 2015 - 2018 Analysis of extracellular matrices that regulate mammalian reproduction
- 2013 - 2018 Functional analysis of fertilization related genes in mice
- 2013 - 2017 Application of CRISPR/Cas9 system for gene manipulation in mice
- 2015 - 2016 A model of xenogeneic fetus pregnancy by the placenta replacement method
- 2012 - 2015 Self and non-self in mouse-rat chimera
- 2012 - 2015 Generation of knock out rat using mouse <-> rat chimera
- 2011 - 2013 Y染色体の精子幹細胞維持に関わる遺伝子領域の同定
- 2008 - 2012 Mechanism of mammalian fertilization and epigenomic regulation of germline cells.
- 2010 - 2011 Development of infertility treatment model using infertile mice and iPS cells
- 2008 - 2009 雄性生殖細胞の分裂再開を制御する分子メカニズムの研究
- 2007 - 2008 Research of proliferation and differentiation in germline cells useing transposon
- 2005 - 2006 遺伝子改変マウスを用いた生殖細胞の性分化の解析
- 2001 - 2006 生殖細胞の性分化の解析
- 2001 - 2006 Analysis of Germ cells sex differentiation
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Papers (53):
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Shunsuke Yuri, Yuki Murase, Ayako Isotani. Generation of rat-derived lung epithelial cells in Fgfr2b-deficient mice retains species-specific development. Development (Cambridge, England). 2024. 151. 1
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Agnes Lee Chen Ong, Toshiya Kokaji, Arisa Kishi, Yoshihiro Takihara, Takuma Shinozuka, Ren Shimamoto, Ayako Isotani, Manabu Shirai, Noriaki Sasai. Erratum: Acquisition of neural fate by combination of BMP blockade and chromatin modification. iScience. 2023. 26. 11. 108257-108257
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Agnes Lee Chen Ong, Toshiya Kokaji, Arisa Kishi, Yoshihiro Takihara, Takuma Shinozuka, Ren Shimamoto, Ayako Isotani, Manabu Shirai, Noriaki Sasai. Acquisition of neural fate by combination of BMP blockade and chromatin modification. iScience. 2023. 26. 10. 107887-107887
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Gema Puspa Sari, Patrick Louis Lagman Hilario, Shunsuke Yuri, Arata Honda, Ayako Isotani. Scheduled simple production method of pseudopregnant female mice for embryo transfer using the luteinizing hormone-releasing hormone agonist. Scientific Reports. 2022. 12. 1
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Takumi Kawasaki, Moe Ikegawa, Kosuke Yunoki, Hifumi Otani, Daisuke Ori, Ken J Ishii, Etsushi Kuroda, Shiki Takamura, Masahiro Kitabatake, Toshihiro Ito, et al. Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung. Cell reports. 2022. 41. 11. 111828-111828
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MISC (10):
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YURI Shunsuke, MURASE Yuki, ISOTANI Ayako. Rat lung analysis in interspecies chimera of mice and rats of different gestation periods. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
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LIM Jonathan Jun-Yong, YURI Shunsuke, ISOTANI Ayako. Investigation of CRISPR/Cas9 system to obtain organ deficient mouse model. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
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大塚正人, 三浦浩美, 磯谷綾子, 伊川正人, 佐藤正宏, 木村穣. C57BL/6Nを遺伝的背景に持つターゲットトランスジェネシス用種マウスの作製と評価. 日本実験動物学会総会講演要旨集. 2014. 61st. 250
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山根睦, かせ田一宏, 磯谷綾子, 伊川正人. BALB/cByJの凍結精子を用いた系統保存の検討. 日本実験動物学会総会講演要旨集. 2014. 61st
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磯谷綾子, 畑山英, かせ田一宏, 伊川正人, 岡部勝, 岡部勝. 異種キメラ動物を使ってES細胞から臓器をつくる. 日本実験動物学会総会講演要旨集. 2011. 58th
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Lectures and oral presentations (27):
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CFB16-HB/Genome Editor Plusを用いた 時短表現型解析
(第116回日本繁殖生物学会年会 2023)
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Rat lung analysis in interspecies chimera of mice and rats of different gestation periods
(The 45th Annual Meeting of the Molecular Biology Society of Japan 2022)
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簡単な偽妊娠マウス作製法の検討
(第69回日本実験動物学会総会 2022)
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全身で赤色蛍光蛋白質を発現するトランスジーンをY染色体上に持つマウスモデル
(第44回日本分子生物学会年会 2021)
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「発生工学技術に魅せられて「キメラ・オタク」になった私」
(第114回日本繁殖生物学会大会 2021)
more...
Works (2):
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生殖細胞の性分化の解析
2002 -
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Analysis of Germ cells sex differentiation
2002 -
Education (2):
- 2001 - 2006 大阪大学大学院 薬学研究科 応用医療薬化学
- 1997 - 2001 Kobe Gakuin University The Faculty of Pharmaceutical Sciences Department of Biopharmacy
Professional career (1):
- Master of Pherma Ceutical Science (Osaka University)
Work history (5):
- 2016/08 - 現在 Nara Institute of Science and Technology Associate Professor
- 2012/08 - 2016/07 Osaka University Immunology Frontier Research Center Specially Appointed Associate Professor
- 2006/08 - 2012/07 Osaka University Research Institute for Microbial Diseases Assistant professor
- 2005/04 - 2006/07 日本学術振興会特別研究員
- 2005/04 - 2006/07 Research Fellow of the Japan Society for the Promotion of Sience
Committee career (4):
- 2022/06 - 現在 国立大学法人動物実験施設協議会 遺伝子組換え委員
- 2022/06 - 現在 国立大学法人動物実験施設協議会 学術情報・広報委員
- 2022/06 - 現在 公益社団法人 日本実験動物学会 教育研修委員
- 2018/07 - 現在 公益社団法人 日本実験動物学会 在任編集員会委員
Awards (7):
Association Membership(s) (3):
日本繫殖生物学会
, JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE
, 日本分子生物学会
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