- 2022 - 2025 新規ニッケル結合性T細胞を基軸としたニッケルアレルギー病態形成機構の解明
- 2019 - 2022 Elucidation of the therapeutic effect of nickel allergy by sublingual immunotherapy
- 2019 - 2022 Study on oral mucosal immune regulation on the axis of activated vitamin D3
- 2017 - 2020 Analysis of the pathogenic roles and control mechanisms of inflammasome in sialadenitis
- 2016 - 2019 Analysis of the mechanisms by which Ni-binding dendritic cells induce Ni allergy
- 2016 - 2018 Study on causes of reduced umami sensitivity
- 2016 - 2018 Basic research for development of effective inducing strategy of sublingual immune tolerance
- 2015 - 2018 Mechanism of sublingual immune tolerance induction by cross-talking with gut mucosal immunity
- 2014 - 2018 Therapeutic innovation in oral mucosal leasions with erosion and ulcer by analyzing antigen presenting ability and autophagy
- 2014 - 2017 Expression of umami-taste-related genes in the tongue.
- 2013 - 2017 Analysis of the human salivary-gland apoptotic pass way for Sjogren's syndrome.
- 2013 - 2016 Thrapeutic effects of biotin on allergic dermatitis through Th balance modulation
- 2012 - 2015 Relationship among metal, resin, infection, and allergy
- 2012 - 2015 Identification and function of Ni-binding carrier protein that induce Ni allergy
- 2011 - 2015 Involvement with differentiation-inducing mechanism of Th17 and autophagy in oral mucosal leasions with erosive and ulcer
- 2012 - 2014 Analysis of pathogenisis of metal allergy using humanized murine model
- 2008 - 2010 A study of mechanisms underlying oral mucous disease on helper T cells and innateimmunity.
- 2009 - 2009 難治性口腔疾患成立における抗原提示細胞としての上皮細胞の役割
- 2007 - 2008 in vivo analysis of HDC activity and cytokine productions by herpes virus group infections
- 2007 - 2008 Regulation of oral immunity and oral manifestation by a novel helper T cell subset
- 2006 - 2007 乳房炎乳汁中の催炎作用を示すラクトフェリン分子のヒト口腔内での催炎作用機構の解明
- 2006 - 2007 Analysis of a murine nickel-allergy model promoted by endotoxin
- 2005 - 2007 The research of the generation and mechanism for the lesion of the ulcer and erosion in oral mucosa
- 2005 - 2006 Immune regulation of oral mucosa and oral mucosal diseases by proteases and their inhibitors
- 2004 - 2006 Analysis of Molecular and Biological Basis of Systemic Effects Provoked by Periodontal Diseases
- 2004 - 2005 Effect of IL-10 over-expression on bone resorption mechanism in apical periodontitis
- 2003 - 2004 Novel bioactivities of neutrophil serine proteases against periodontopathic bacteria in innate immunity
- 2002 - 2003 Periodontal Diseases as a Hypersensitivity Reaction Based on Innate Immune Responses in Periodontal Tissues
- 2001 - 2002 Regulation of oral mucosal immunity in human oral epithelial cells and periodontitis
- 2000 - 2001 Inhibition of superantigen-induced apoptosis by LPS
- 2000 - 2001 Recognition of Cell-Surface Components of Bacteria in Innate Immune System, with Special Reference to the Role of Toll-Like Receptors
- 1999 - 2000 Analysis of endotoxin antagonism of lipoteichoic acids from oral streptococci
- 1998 - 1999 The etiological significance of superantigen in periodontal disease and its possible role
- 1998 - 1999 Bacterial cell surface amphiphiles and periodontal diseases - Study on the role of CD14 molecule in periodontal tissues -
- 1997 - 1998 Activation of human gingival epithelial cells by black-pigmented bacteria
- 1997 - 1998 Inflammatory and anti-inflammatory actions of bisphosphonates, inhibitors of bone resorption
- 1996 - 1997 Superantigen Produced by oral Streptococci and oral mucosal diseases.
- 1993 - 1994 Unusual increase of extrathymic T cells in the liver of autoimmune MRL-1pr/1pr mice.
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