Rchr
J-GLOBAL ID：200901036145308243   Update date: Sep. 19, 2024

Takahashi Masahide

タカハシ マサヒデ | Takahashi Masahide
Affiliation and department：
Fujita Health University International Center for Cell and Gene Therapy

About Fujita Health University International Center for Cell and Gene Therapy


Job title： Director, Designated Professor
Other affiliations (1)：
  • Fujita Health University
Research field  (1)： Experimental pathology
Research keywords  (9)： neurogenesis ,  angiogenesis ,  receptor tyrosine kinase ,  neurotrophic factor ,  enteric nervous system ,  neuronal differentiation ,  invasion and metastasis of cancer cells ,  cell growth ,  cancer
Research theme for competitive and other funds  (45)：
  • 2020 - 2023 がんの線維化におけるMeflinの機能解析と新規治療法の開発研究
  • 2019 - 2022 Functional analysis of CD109 in tumor progression using osteosarcoma cells and tissue
  • 2014 - 2019 Girdinファミリー分子の機能と精神神経疾患・がんの病態形成における役割
  • 2013 - 2017 Phosphoproteomic analysis of RET kinase signal in MTC model mice
  • 2014 - 2016 Molecular Mechanisms of Collective Migration of Cancer Cells
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Papers (220)：
  • Hyogo Naoi, Yuzo Suzuki, Asuka Miyagi, Ryo Horiguchi, Yuya Aono, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, et al. CD109 Attenuates Bleomycin-induced Pulmonary Fibrosis by Inhibiting TGF-β Signaling. Journal of immunology (Baltimore, Md. : 1950). 2024. 212. 7. 1221-1231
  • Ryota Ando, Yukihiro Shiraki, Yuki Miyai, Hiroki Shimizu, Kazuhiro Furuhashi, Shun Minatoguchi, Katsuhiro Kato, Akira Kato, Tadashi Iida, Yasuyuki Mizutani, et al. Meflin is a marker of pancreatic stellate cells involved in fibrosis and epithelial regeneration in the pancreas. The Journal of pathology. 2023
  • Yuya Aono, Yuzo Suzuki, Ryo Horiguchi, Yusuke Inoue, Masato Karayama, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, et al. CD109 on Dendritic Cells Regulates Airway Hyperreactivity and Eosinophilic Airway Inflammation. American journal of respiratory cell and molecular biology. 2022. 68. 2. 201-212
  • 迫田 朋佳, 江崎 寛季, 安藤 良太, 宮井 雄基, 飯田 忠, 松山 誠, 白木 之浩, 三井 伸二, 西田 佳弘, 高橋 雅英, et al. 骨肉腫におけるMeflin陽性細胞を標的とした抗体薬物複合体の研究開発(An Effective Therapy that Antibody-Drug Conjugates Targeting Meflin(+) Cells for Osteosarcoma). 日本癌学会総会記事. 2022. 81回. E-2021
  • Yuki Miyai, Daisuke Sugiyama, Tetsunari Hase, Naoya Asai, Tetsuro Taki, Kazuki Nishida, Takayuki Fukui, Toyofumi Fengshi Chen-Yoshikawa, Hiroki Kobayashi, Shinji Mii, et al. Meflin-positive cancer-associated fibroblasts enhance tumor response to immune checkpoint blockade. Life Science Alliance. 2022. 5. 6. e202101230-e202101230
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MISC (199)：
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Books (32)：
  • サイトカイン・増殖因子キーワード事典;GDNFファミリー、RET,、GDNFファミリー受容体複合体
    羊土社 2015
  • Protein Modifications in Pathogenic Dysregulation of Signaling; Critical Roles of the AKT Substrate Girdin in Disease Initiation and Progression
    2015
  • Robbins Basic Pathology 9th Edition
    2014
  • がんー疾患モデルの作製と利用 RET
    株式会社 エル・アイ・シー 2012
  • Aktシグナルによるがん細胞の運動制御ーアイソフォームに依存する分子機構
    実験医学増刊(羊土社) 2012
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Lectures and oral presentations  (5)：
  • Roles of the Akt substrate Girdin in cancer progression and angiogenesis
    (International Symposium on Nanomedicine 2014)
  • Roles of the Akt substrate Girdin in cell motility
    (1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling 2013)
  • Roles of the Akt substrate Girdin in cancer progression, angiogenesis and neurogenesis
    (Global Center of Excellence (COE) Program, The 4th International Symposium 2012)
  • Roles of the Akt substrate Girdin in cancer progression and angiogenesis
    (Global center of excellence (COE) Program, the 3rd International Symposium 2011)
  • Roles of RET tyrosine kinase and Akt signaling in human disease
    (Wihship Cancer Institute, Elkin Lecture Series 2011)
Education (2)：
  • - 1983 Nagoya University Graduate School, Division of Medicine
  • - 1979 Nagoya University Faculty of Medicine
Professional career (1)：
  • Medical Doctor (Nagoya University)
Work history (5)：
  • 2020/04 - 現在 Fujita Health University International Center for Cell and Gene Therapy Director, Designated Professor
  • 2020/04 - 現在 Fujita Health University
  • 2017/04 - 2020/03 Nagoya University Trustee / Vice President Professor, Graduate School of Medicine
  • 2013/04 - 2020/03 Nagoya University Graduate School of Medicine Center for Neural Disease and Cancer Division Professor
  • 2004/10/01 - 2013/03/31 Nagoya University Graduate School of Medicine Center for Neural Disease and Cancer Professor
Awards (8)：
  • 2020/11 - Japanese Goverment Medal with Purple Ribbon
  • 2020/02 - Princess Takamatsu Cancer Research Fund Princess Takamatsu Cancer Research Fund Prize
  • 2019/11 - Japan Medical Association Medical Award of The Japan Medical Association
  • 2010/05 - Chunichi Shimbun Co. Ltd. Chunichi Cultural Award
  • 2006/03 - Yomiuri Newspaper Co. The Yomiuri-Tokai Medical Award
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Association Membership(s) (3)：
日本分子生物学会 ,  日本病理学会 ,  日本癌学会
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