Rchr
J-GLOBAL ID:200901036271492203   Update date: Jul. 13, 2022

Yokokawa Akitomo

ヨコカワ アキトモ | Yokokawa Akitomo
Affiliation and department:
Job title: associate professor
Homepage URL  (1): https://www.ps.toyaku.ac.jp/rinshoyakugaku/
Research field  (2): Clinical pharmacy ,  Pharmaceuticals - health and biochemistry
Research keywords  (4): 分析化学 ,  臨床薬学 ,  Analytical Chemistry ,  Clinical Pharmacy
Research theme for competitive and other funds  (2):
  • 2012 - 2015 The relationship between 11beta-hydroxysteroid dehydrogenase 2 enzyme activity and blood pressure in patients with renal disease
  • 2004 - 2006 Evaluation of in vivo enzymatic activity of cortisol metabolism associated with hypertension
Papers (26):
  • 柴崎浩美, 横川彰朋, 降幡知巳. LC-MS/MSによるcortisolと6β-hydroxycortisolの測定に及ぼす血液採取時の抗凝固剤及び保存状態の影響. 分析化学. 2022. 71. 6. 357-363
  • Seiya Ohki, Miyu Kunimatsu, Shingo Ogawa, Hiroki Takano, Tomomi Furihata, Hiromi Shibasaki, Akitomo Yokokawa. Development and Validation of an LC-MS/MS-Based Method for Quantifying Urinary Endogenous 6-Hydroxymelatonin. Chemical and Pharmaceutical Bulletin. 2022. 70. 5. 375-382
  • Akitomo Yokokawa, Aya Kitano, Daichi Tanaka, Kai Higashi, Shun Yanada, Kohei Shimizu, Tomomi Furihata, Hiromi Shibasaki. Effects of 11β-hydroxysteroid dehydrogenase 2 activity on the prediction accuracy of plasma unbound cortisol concentration based on salivary cortisol. Medical Mass Spectrometry. 2022. 6. 45-51
  • Ryohei Hirano, Akitomo Yokokawa, Tomomi Furihata, Hiromi Shibasaki. Dried blood spots analysis of 6β-hydroxycortisol and cortisol using liquid chromatography/tandem mass spectrometry for calculating 6β-hydroxycortisol to cortisol ratio. Journal of mass spectrometry : JMS. 2021. 56. 12. e4790
  • Akitomo Yokokawa, Shun Kaneko, Sayuri Endo, Yuki Minowa, Hideaki Ayukawa, Ryohei Hirano, Fumio Nagashima, Daisuke Naruge, Naohiro Okano, Takaaki Kobayashi, et al. Effect of UGT1A1, CYP3A and CES Activities on the Pharmacokinetics of Irinotecan and its Metabolites in Patients with UGT1A1 Gene Polymorphisms. European journal of drug metabolism and pharmacokinetics. 2021. 46. 2. 317-324
more...
MISC (87):
  • 大木 聖矢, 尾川 慎悟, 高野 大輝, 島崎 隼人, 深江 桃花, 降幡 知巳, 柴崎 浩美, 横川 彰朋. 新規CYP1A2活性評価法の開発を目指した内因性Melatonin部分代謝クリアランスの算出. TDM研究. 2022. 39. 2. 125-125
  • 大木聖矢, 横川彰朋, 國松海佑, 尾川慎悟, 高野大輝, 降幡知巳, 柴崎浩美. Development of deconjugation reaction conditions in measurement of urinary melatonin metabolites using LC-MS/MS. 日本薬学会年会要旨集(Web). 2021. 141年会. 29V11-am01S
  • 横川彰朋, 出口紗瑛子, 莚田侑香, 大嶋梨紗, 降幡知巳, 柴崎浩美. Development of LC-MS/MS method for determination of cystatin C in human serum using stable isotope-labeled peptide as an internal standard. 日本薬学会年会要旨集(Web). 2021. 141年会. 28P01-079
  • 柴崎浩美, 横川彰朋, 降幡知巳. The effects of anticoagulants and storage conditions on plasma concentrations of 6β-hydroxycortisol and cortisol as determined by LC-MS/MS. JSBMS Letters. 2021. 46. Supplement
  • 大木聖矢, 國松海佑, 尾川慎悟, 高野大輝, 降幡知巳, 柴崎浩美, 横川彰朋. Development of a LC-MS/MS-based quantification method for urinary endogenous 6-hydroxymelatonin to evaluate melatonin secretion. JSBMS Letters. 2021. 46. Supplement
more...
Patents (2):
Books (2):
  • テーラーメイド医療
    京都廣川書店 2010
  • テーラーメイド医療 第2版 -薬物治療の個別化-
Education (4):
  • - 2000 Tokyo University of Pharmacy and Life Sciences
  • - 2000 Tokyo University of Pharmacy and Life Science
  • - 1997 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
  • - 1997 Tokyo University of Pharmacy and Life Science
Professional career (2):
  • (BLANK) (Tokyo University of Pharmacy and Life Science)
  • 博士(薬学) (東京薬科大学)
Work history (1):
  • 2000 - 現在 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
Awards (1):
  • 2013/08 - 日本臨床化学会 学会賞 「奨励賞」 ヒトin vivo における11β-hydroxysteroid dehydrogenase 2の活性評価法の開発
Association Membership(s) (6):
International Association of Therapeutic Drug Monitoring & Clinical Toxicology ,  日本臨床化学会 ,  日本医用マススペクトル学会 ,  日本TDM学会 ,  日本薬物動態学会 ,  日本薬学会
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