Hirata Takako

ヒラタタカコ | Hirata Takako

Affiliation and department：
Job title： Professor

Research field (1)： Immunology

Research keywords (3)：分子生物学 , 細胞生物学 , 免疫学

Research theme for competitive and other funds (13)：

2022 - 2025 原発性免疫不全症における免疫不全と自己免疫の合併機序
2019 - 2022 Control mechanisms of regulatory T cell homeostasis by ERM proteins
2016 - 2019 Molecular mechanisms and control of immune cell migration to skin and mucosa
2013 - 2016 Molecular mechanisms and control of immune cell migration to inflamed sites
2010 - 2012 Control of leukocyte migration to inflamed sites and its application to the treatment of refractory inflammatory diseases

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Papers (47)：

Koji Terada, Kenta Kondo, Hirohito Ishigaki, Ayaka Nagashima, Hiroki Satooka, Seiji Nagano, Kyoko Masuda, Teruhisa Kawamura, Takako Hirata, Kazumasa Ogasawara, et al. Isolation of TCR genes with tumor-killing activity from tumor-infiltrating and circulating lymphocytes in a tumor rejection cynomolgus macaque model. Molecular therapy oncolytics. 2022. 24. 77-86
Hiroki Satooka, Makoto Matsui, Satoko Ichioka, Yuzuki Nakamura, Takako Hirata. The ERM protein moesin regulates natural killer cell homeostasis in vivo. Cellular immunology. 2022. 371. 104456-104456
Jun Kitazawa, Fuminori Kimura, Akiko Nakamura, Aina Morimune, Tetsuro Hanada, Tsukuru Amano, Shunichiro Tsuji, Kyoko Kasahara, Hiroki Satooka, Takako Hirata, et al. Alteration in endometrial helper T-cell subgroups in chronic endometritis. American Journal of Reproductive Immunology. 2020
Tomomi Sato, Hiroki Satooka, Satoko Ichioka, Yoshihiro Maruo, Takako Hirata. Citrullinated fibrinogen is a target of auto-antibodies in interstitial lung disease in mice with collagen-induced arthritis. International immunology. 2020. 32. 8. 533-545
Makoto Matsui, Daisuke Nagakubo, Hiroki Satooka, Takako Hirata. A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model. Biochemical and biophysical research communications. 2020. 526. 3. 599-606

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MISC (42)：

SATOOKA Hiroki, NAKAMURA Yuzuki, TODO Kagefumi, HIRATA Takako. Redox-mediated SOCS3 expression in regulatory T cells is involved in the development of autoimmunity. 日本免疫学会総会・学術集会記録(CD-ROM). 2021. 50
TODO Kagefumi, SATOOKA Hiroki, HIRATA Takako. Production of secreted form of IgD during immune responses. 日本免疫学会総会・学術集会記録(CD-ROM). 2021. 50
茶谷元晴, 茶谷元晴, 藤井貴之, 藤堂景史, 大野美紀子, 西清人, 平田多佳子, 安藤朗, 西英一郎. TおよびB細胞のナルディライジンによる抗体産生調節機構の解明. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2021. 26th
寺田晃士, 石垣宏仁, 近藤健太, 長嶋彩花, 里岡大樹, 永野誠治, 増田喬子, 川村晃久, 河本宏, 平田多佳子, et al. カニクイザルの腫瘍拒絶モデルにおける腫瘍浸潤T細胞からの腫瘍殺傷能をもつTCR遺伝子の単離. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
ASANO Kyoko, TODO Kagefumi, HIRATA Takako. Phagocytic cells are induced by activation of resting splenic B cells. 日本免疫学会総会・学術集会記録(CD-ROM). 2019. 48

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Books (6)：

Encyclopedia of immunobiology
Academic Press 2016 ISBN:9780123742797
Lymphocyte homing to the skin-immunology, immunopathology, and therapeutic perspectives
CRC Press 2005 ISBN:9780849325281
Hyaluronan-structure, metabolism, biological activities, therapeutic applications
Matrix Biology Institute 2005 ISBN:9780977135905
キーワードで理解する免疫学イラストマップ
羊土社 2004 ISBN:9784897065779
KEY WORD 1996-'97 炎症・免疫系
先端医学社 1996 ISBN:491589231x

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Lectures and oral presentations (4)：

カニクイザルの腫瘍浸潤T細胞から腫瘍殺傷能を有するTCR遺伝子を単離する
(日本がん免疫学会総会プログラム・抄録集 2020)
アレルギーアナフィラキシー、気道炎症/喘息およびその他(皮膚炎を除く) I型過敏症におけるIgD発現細胞の関与(Allergy-2: Anaphylaxis, airway inflammation/asthma and others (except dermtitis) Involvement of IgD-expressing cells in type I hypersensitivity)
(日本免疫学会総会・学術集会記録 2019)
関節リウマチ、シェーグレン症候群、その他の自己免疫疾患制御性T細胞におけるレドックスを介したシグナル伝達は自己免疫の発生に関与している(Rheumatoid arthritis, Sjogren's syndrome and other autoimmune diseases Redox-mediated signaling in regulatory T cells is involved in the development of autoimmunity)
(日本免疫学会総会・学術集会記録 2019)
B細胞発生、活性化、機能の調節貪食細胞は脾臓の休眠B細胞の活性化により誘導される(Regulation of B cell development, activation, and function Phagocytic cells are induced by activation of resting splenic B cells)
(日本免疫学会総会・学術集会記録 2019)

Education (2)：

Professional career (1)：

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