Rchr
J-GLOBAL ID：200901036459755015
Update date: Jul. 18, 2022
Ishimi Yukio
イシミ ユキオ | Ishimi Yukio
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Research field (1)：
Molecular biology
Research keywords (1)：
DNA replication, MCM proteins, DNA helicase, DNA replication checkpoint system, human proteins involved in DNA replication
Research theme for competitive and other funds (3)：
2014 - 2017 MCMを中心としたDNA複製因子の集合と機能抑制機構の解明
2011 - 2013 DNA複製フォークでの分子集合と複製ヘリカーゼの役割の解明
2005 - 2008 MCMヘリカーゼ機能発現調節機構の解明
Papers (32)：
Wang, X, Ishimi, Y. Function of the amino-terminal region of human MCM4 in helicase activity. J. Biochem. 2018. 164. 449-460
Tsuji, M, Tanaka, T, Nagashima, R, Sagisaka, Y, Tosen, Y, Nishide, Y, Ishimi, Y, ishimi, Y. Effect of daidzein and equal on DNA replication in MCF-7 cells. J. Biochem. 2018. 163. 371-380
Ruriko Tatsumi, Yukio Ishimi. An MCM4 mutation detected in cancer cells affects MCM4/6/7 complex formation. JOURNAL OF BIOCHEMISTRY. 2017. 161. 3. 259-268
Hosoi, A, Sakairi, T, Ishimi, Y. Binding of MCM-interacting proteins to ATP-binding site in MCM6. Research Reports in Biology. 2016. 7. 31-40
Yukio Ishimi, Daiki Irie. G364R mutation of MCM4 detected in human skin cancer cells affects DNA helicase activity of MCM4/6/7 complex. JOURNAL OF BIOCHEMISTRY. 2015. 157. 6. 561-569
ｍore...
MISC (1)：
Ishimi, Y. Regulation of MCM2-7 helicase. Genes Genet. System. 2018. 93. 125-133
Lectures and oral presentations (15)：
MCM相互作用因子はMCM6のATP結合部位に結合する
(第39回日本分子生物学会年会 2016)
MCMヘリカーゼの保存性と多様性
(日本進化学会第18回東京大会 2016)
ヒトMCM-BPタンパク質の機能解析
(日本分子生物学会年会 2009)
乳がんを引き起こすMCM4タンパク質変異の解析
(日本分子生物学会年会 2009)
ヒトRPAに直接的に相互作用するタンパク質の同定
(日本分子生物学会年会 2009)
ｍore...
Professional career (1)：
薬学博士 (東京大学)
Work history (4)：
2004/10 - Prof. Faculty of Science, Ibaraki University
1988/09 - 2004/09 member, Mitsubishi Kagaku Institute of Life Sciences
1983/07 - 1988/08 assistant professor, Faculty of Pharmaceutical Sciences, University of Tokyo
Ibaraki University Graduate School of Science and Engineering (Science), Department of Science (Biological Sciences Course) Professor
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