Rchr
J-GLOBAL ID:200901037026434814
Update date: Mar. 16, 2024
Nakagawa Kiyotaka
ナカガワ キヨタカ | Nakagawa Kiyotaka
Affiliation and department:
Job title:
Professor
Homepage URL (1):
https://www.agri.tohoku.ac.jp/kinoubun/index-j.html
Research field (2):
Food sciences
, Applied biochemistry
Research keywords (2):
分析化学
, 食品化学
Research theme for competitive and other funds (27):
- 2022 - 2025 最適な光酸化制御を目指した食品・生体に生じる光酸化機構の解明
- 2022 - 2025 脂質酸化全貌情報の精緻化から創造する食品の未来品質・ヒトの健康社会
- 2020 - 2023 Effect of lipid hydroperoxide on cancer progression and its mechanism of action
- 2019 - 2022 Evaluation of organ accumulation and metabolism of 1-deoxynojirimycin by long-term administration
- 2019 - 2022 Elucidation of the lipid oxidation mechanisms and their optimal control leading to a healthy- and food-based society of the future through the analysis of lipid hydroperoxides isomers
- 2019 - 2021 Challenges into the definite control of human odor by regulating the oxidation of a newly conceptualized terpenoid "squalene"
- 2017 - 2020 Identification of a novel gene causing cholesterol synthesis deficiency
- 2017 - 2019 Possibility creation of new vitamin-like component derived from the elucidation of absorption metabolism of rice characteristic component g-oryzanol
- 2016 - 2019 Preparation of 15N labled 1-deoxynojirimycin and evaluation of its absorption and organ migration
- 2016 - 2019 Study on n-3 fatty acid metabolism and transport in perinatal period
- 2015 - 2018 Elucidation of the mechanism for lipid hydroperoxide generation, its involvement in diseases, and its suppression by dietary components
- 2013 - 2018 Elucidation of new physiological functions such as anti-obesity and anti-inflammation of food Maillard reaction products
- 2015 - 2017 Analysis for nonalcoholic steatohepatitis development mechanism using focused microarray analysis aimed for elucidation of food effect.
- 2015 - 2017 Elucidation of cellular uptake of curcumin: its relation to biological activity
- 2014 - 2017 Impaired glucose tolerance as a risk factor for arteriosclerotic disease: analysis in new model mice
- 2013 - 2015 Invention of nano delivery systems with food antioxidants in the body.
- 2012 - 2015 Alzheimer's disease (AD) biomarkers and new food ingredients useful for AD prevention
- 2012 - 2014 Identification and application of vitamin E synthesis gene for tocotrienol production.
- 2011 - 2013 Mass production of 15N labeled DNJ to evaluate the absorption and excretion of 1-deoxynojirimycin
- 2011 - 2012 The apoptosis suppression effect on brain neuron of plasmalogen
- 2008 - 2012 Studies on lipid peroxidation in human disease: its modulation from the view point of food chemistry
- 2010 - 2011 Peroxidation of skin lipids : a role of nutraceutical foods as the inhibitor
- 2009 - 2010 ピロロキノリンキノン新規活性代謝物の発見と食品応用
- 2007 - 2009 Study on synergistic effect of flavonoids and other compounds on availability of flavonoids in vivo
- 2007 - 2008 ビタミンEの新規生理活性である皮膚抗アレルギー作用の分子機構と展開
- 2006 - 2007 Activation of innate immune responses and its regulation by NKT cells and γδT cells in fungal infection
- 2004 - 2005 C型肝炎と膜リン脂質過酸化:食品機能成分による肝炎・肝細胞癌の予防
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Papers (320):
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Kanji Aoyagi, Shunji Kato, Daisuke Isaka, Yoshinori Sekiguchi, Yurika Otoki, Hidetaka Uehara, Kiyotaka Nakagawa. Preparation of saturated fatty acid hydroperoxide isomers and determination of their thermal decomposition products - 2-alkanones and lactones. Food chemistry: X. 2024. 21. 101074-101074
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Naoya Yamada, Tadayoshi Karasawa, Junya Ito, Daisuke Yamamuro, Kazushi Morimoto, Toshitaka Nakamura, Takanori Komada, Chintogtokh Baatarjav, Yuma Saimoto, Yuka Jinnouchi, et al. Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis. Nature communications. 2024. 15. 1. 2195-2195
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Chikara Kato, Ibuki Kusumoto, Shunji Kato, Yurika Otoki, Junya Ito, Hirono Totsuka, Arun Rajgopal, Jina Hong, Kiyotaka Nakagawa. Induction of ferroptosis in human keratinocyte HaCaT cells by squalene hydroperoxide: Possible prevention of skin ferroptosis by botanical extracts. Biochemical and biophysical research communications. 2024. 698. 149553-149553
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Hirotada Saito, Shunji Kato, Naoki Shimizu, Takumi Takahashi, Mirinthorn Jutanom, Junya Ito, Satoshi Kasatani, Kiyotaka Nakagawa. LC-MS/MS analysis of milk triacylglycerol hydroperoxide isomers which are generated corresponding to the photo- and thermal-oxidation. Food Research International. 2024. 178
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Masanari Kuwabara, Jun Sasaki, Yasuyoshi Ouchi, Shinichi Oikawa, Kiyotaka Nakagawa, Masao Sato, Shinji Koba, Suminori Kono, Tetsunori Saikawa, Hidenori Arai. Higher Cholesterol Absorption Marker at Baseline Predicts Fewer Cardiovascular Events in Elderly Patients Receiving Hypercholesterolemia Treatment: The KEEP Study. Journal of the American Heart Association. 2024. e031865
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MISC (318):
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加藤俊治, 乙木百合香, 仲川清隆. 金属イオン付加体を用いた質量分析による脂質構造解析. 2022. 22. 287-295
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渡邊慎平, 仲川清隆. 「スペクトロメトリーによる脂質分析の今」の企画と編集にあたって. オレオサイエンス. 2022. 22. 264
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Hisanori Kato, Kiyotaka Nakagawa. Importance of Nutrition in Japan and the World. The Nutrition Society Gazette, Summer 2022. 2022. 20
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仲川清隆. 「次世代放射光の油化学関連領域への活用」の編集にあたって. 2022. 22. 4
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真鍋祐樹, 瀧本秀美, 仲川清隆. 東京栄養サミット2021に向けた日本栄養学学術連合の取組について. 明日の食品産業. 2021. 12
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Books (45):
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米の機能性食品化と新規利用技術・高度加工技術の開発
2022
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ビタミン・バイオファクター総合辞典
2021
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LC-MS/MSを用いた菜種油の酸化メカニズム研究の事例
(株)技術情報協会 2020
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茶ポリフェノールの生理機能と応用展開
シーエムシー出版 2019
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宮城の医療と健康
河北新報社, 84-86 (2019) 2019
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Lectures and oral presentations (1,186):
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Study of the acidic compounds derived from triacylglycerol that contribute to acid value increment.
(22nd IUNS-International Congress of Nutrition 2022)
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Elucidation of novel γ-oryzanol species in rice bran oil and processed foods containing rice bran oil.
(22nd IUNS-International Congress of Nutrition 2022)
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Non-destructive analysis of lignan in sesame oil.
(22nd IUNS-International Congress of Nutrition 2022)
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Improvement of storage stability of vegetable oils by using rice bran oil.
(22nd IUNS-International Congress of Nutrition 2022)
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Water in oil emulsion system modifies absorption profile of green tea catechins in the body and also masks their bitter taste: Evaluation in human subjects.
(22nd IUNS-International Congress of Nutrition 2022)
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Education (3):
- - 1999 Tohoku University Graduate School, Division of Agriculture 食糧化学専攻
- - 1996 Tohoku University Graduate School, Division of Agriculture 食糧化学専攻
- - 1994 Tohoku University Faculty of Agriculture 食糧化学科
Professional career (1):
Work history (8):
- 2016/04 - 現在 東北大学大学院農学研究科 教授
- 2007/04 - 2016/03 東北大学大学院農学研究科 准教授
- 2013/04 - 2013/10 米国タフツ大学Jean-Mayerヒトの老化と栄養に関する研究所 客員研究員
- 2004/11 - 2007/03 東北大学大学院農学研究科 助教授
- 2003/04 - 2004/03 東北大学大学院農学研究科 助手
- 2000/01 - 2002/12 科学技術振興事業団 科学技術特別研究員 研究員 科学技術振興事業団 科学技術特別研究員
- 1999/04 - 2000/12 日本学術振興会特別研究員(PD) 研究員 日本学術振興会特別研究員(PD)
- 1998/04 - 1999/03 日本学術振興会特別研究員(DC2) 研究員 日本学術振興会特別研究員(DC2)
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Association Membership(s) (15):
日本食品分析学会
, 日本分析化学会
, 日本生化学会
, ビタミンE研究会
, 国際メイラード学会
, 日本メイラード学会
, 日本ビタミン学会
, 日本過酸化脂質・抗酸化物質学会(旧 生体パーオキサイド研究会)
, 日本油化学会
, 日本食品科学工学会
, 日本脂質生化学会
, 日本栄養・食糧学会
, 日本農芸化学会
, 日本脂質栄養学会
, 日本フードファクター学会
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