Rchr
J-GLOBAL ID:200901037373527415
Update date: Apr. 17, 2024
Nakano Kazuhiko
ナカノ カズヒコ | Nakano Kazuhiko
Affiliation and department:
Job title:
Professor
Other affiliations (1):
-
Osaka University
Graduate School of Dentistry Course for Oral Sciences
Professor
Research field (2):
Developmental dentistry
, Bacteriology
Research keywords (8):
Infective endocarditis
, Odontogenic infection
, Pediatric Dentistry
, 全身疾患
, 口腔細菌
, 感染性心内膜炎
, 菌血症
, 小児歯科学
Research theme for competitive and other funds (34):
- 2023 - 2026 S. mutans コラーゲン結合タンパクに着目した IgA 腎症発症機構の解明
- 2022 - 2025 全身疾患との関連性が高いう蝕病原性細菌の定着環境の解明と定着予防法の追究
- 2021 - 2025 う蝕原性細菌のコラーゲン結合能に着目した低中所得国の全身疾患低減に向けた新戦略
- 2021 - 2024 う蝕原性細菌が誘発する全身疾患の制御に向けた新たな病原メカニズムの解明
- 2021 - 2024 小児期のう蝕および口腔内環境に着目したピロリ菌定着の予防法追究に対する新戦略
- 2020 - 2023 Elucidation of the effect of Microorganism of the body on the origin and rupture of the intracranial aneurysms and development of preventive measure of the subarachnoid hemorrhage
- 2020 - 2023 歯科領域からの革新的治療法の開発を目指した口腔細菌に起因するIgA腎症の病態解明
- 2019 - 2022 Association of dental disease and kidney disease: Examination of oral specimens and renal biopsy / tonsil specimens of IgA nephropathy patients
- 2019 - 2021 A study to elucidate the mechanism of intracerebral heorrhage induced by collagen-binding Streptococcus mutans and to develop a novel preventive therapy
- 2019 - 2021 Role of interorganelle communication in mineralization
- 2018 - 2021 Elucidation of effects of cariogenic bacteria on organ-linked network due to oral barrier breakdown
- 2017 - 2021 Establishment of international liaison between medical doctors and dentists for the purpose of reduction of stroke in Nigeria and Kenya
- 2017 - 2020 Mechanism of aggravation of IgA nephropathy by mutans streptococci
- 2015 - 2019 Clinical investigation of the cerebrovascular diseases aggravation caused by dental caries pathogens and establishing simplified technique for detecting the high risk group.
- 2016 - 2018 Study to understand mechanism of hemorrhagic stroke induced by oral bacteria
- 2015 - 2018 Specification of route of Helicobacter pylori infection and construction of preventive approaches for gastric diseases in pediatric dentistry field
- 2015 - 2018 Construction of global standard molecular epidemiological method for identification of the children at risk for severe dental caries
- 2015 - 2018 Basic and clinical approaches for dental problems associated with skeletal diseases
- 2015 - 2017 Possible involvement of mutans streptococci in development of pediatric kidney disease
- 2015 - 2017 Elucidation of mechanism of non-alcoholic steatohepatitis aggravation caused by mutans streptococci
- 2013 - 2015 Establishment of early screening method for gastric diseases caused by Helicobacter pylori
- 2012 - 2015 Pathogenic mechanism for aggravation of inflammatory bowel diseases caused by oral bacteria and specification of highly virulent strains
- 2012 - 2015 Construction of system in dentistry field to prevent preterm low birth weight delivery
- 2011 - 2014 Investigation of mechanism of systemic diseases caused by oral bacteria and development of preventive procedures
- 2011 - 2013 Study on canine periodontal disease as zoonosis
- 2009 - 2011 Elucidation of mechanism for development of cerebrovascular diseases associated with oral bacteria and pursuit of preventive approach
- 2007 - 2010 Analysis of virulence factors in cariogenic bacteria for cardiovascular diseases
- 2007 - 2008 P.gingivalis線毛遺伝子型の同定と歯周炎発症高リスク者特定への応用
- 2006 - 2008 Molecular biological analyses of virulence factors for infective endocarditis caused by oral streptococci
- 2005 - 2006 感染性心内膜炎動物モデル系の確立と口腔レンサ球菌における病原性の検討
- 2004 - 2006 Molecular analysis of cell surface structures of Streptococcus mutans for virulence of infective endocarditis
- 1996 - Analysis of virulence factors of infective endocarditis caused by oral streptococci
- 1996 - 口腔レンサ球菌による感染性心内膜炎における病原因子の解析
- う蝕原性細菌の全身疾患に関する病原因子の解析
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Papers (454):
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Yuko Ogaya, Tamami Kadota, Masakazu Hamada, Ryota Nomura, Kazuhiko Nakano. Characterization of the unique oral microbiome of children harboring Helicobacter pylori in the oral cavity. Journal of Oral Microbiology. 2024
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Akari Nishi, Azumi Hirata, Atsushi Mukaiyama, Shun-ichi Tanaka, Ryota Nomura, Kazuhiko Nakano, Kazufumi Takano. Role of N1-Domain, Linker, N2-Domain, and Latch in the Binding Activity and Stability of the Collagen-Binding Domain for the Collagen-Binding Protein Cbm from Streptococcus mutans. Physchem. 2024
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Junya Yasuda, Hidemi Yasuda, Ryota Nomura, Saaya Matayoshi, Hiroaki Inaba, Enrique Gongora, Naoki Iwashita, So Shirahata, Noriyuki Kaji, Tatsuya Akitomo, et al. Investigation of periodontal disease development and Porphyromonas gulae FimA genotype distribution in small dogs. Scientific reports. 2024. 14. 1. 5360-5360
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Saaya Matayoshi, Fumikazu Tojo, Yuto Suehiro, Makoto Okuda, Misato Takagi, Marin Ochiai, Maika Kadono, Yusuke Mikasa, Rena Okawa, Ryota Nomura, et al. Effects of mouthwash on periodontal pathogens and glycemic control in patients with type 2 diabetes mellitus. Scientific reports. 2024. 14. 1. 2777-2777
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Kazuma Kokomoto, Rina Kariya, Aya Muranaka, Rena Okawa, Kazuhiko Nakano, Kazunori Nozaki. Automatic dental age calculation from panoramic radiographs using deep learning: a two-stage approach with object detection and image classification. BMC oral health. 2024. 24. 1. 143-143
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MISC (363):
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臼田桃子, 亀谷茉莉子, 秋友達哉, 末廣雄登, 又吉紗綾, 中野将志, 光畑智恵子, 仲周平, 仲野道代, 仲野和彦, et al. ホタテ貝由来アパタイトのStreptococcus mutansに対する齲蝕予防効果の分析. 小児歯科学雑誌. 2023. 61
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松岡大貴, 仲周平, 後藤花奈, 野村良太, 仲野和彦, 仲野道代. Molecular biological investigation of the binding of human IgA by collagen-binding protein Cnm. 小児歯科学雑誌. 2023. 61
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奥田真琴, 又吉紗綾, 東條文和, 仲周平, 仲野道代, 野村良太, 仲野和彦. Relationship of collagen-binding protein-positive Streptococcus mutans strain distribution with dental caries incidence in children. 小児歯科学雑誌. 2023. 61
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野村良太, 長澤康行, 三崎太郎, 仲周平, 仲野道代, 仲野和彦. ラットおよびマウスを用いた口腔細菌のIgA腎症発症への影響の検討. 日本腎臓学会誌(Web). 2023. 65. 3
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三崎太郎, 仲周平, 鈴木仁, 李明峰, 青木良輔, 長澤康行, 松岡大貴, 伊藤誓悟, 野村良太, 仲野道代, et al. 口腔内のcnm遺伝子陽性S.mutansとIgA腎症患者の糖鎖異常IgA沈着の関連性. 日本腎臓学会誌(Web). 2023. 65. 3
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Education (1):
- 1990 - 1996 Osaka University School of Dentistry School of Dentistry
Professional career (1):
Work history (7):
Awards (5):
- 2008 - 平成19年度大阪大学教育・研究功績賞
- 2007 - 平成18年度日本小児歯科学会学術賞
- 2007 - 平成18年度大阪大学歯学会優秀研究奨励賞
- 2004 - 第7回大阪大学歯学部弓倉学術奨励賞
- 2003 - 平成14年度日本小児歯科学会奨励賞
Association Membership(s) (5):
国際歯科研究学会
, 日本小児歯科学会
, 国際小児歯科学会
, 日本小児科学会
, ヨーロッパう蝕学会
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