Rchr
J-GLOBAL ID：200901037373527415
Update date: Nov. 15, 2024
Nakano Kazuhiko
ナカノ カズヒコ | Nakano Kazuhiko
Affiliation and department：
Job title：
Professor
Other affiliations (1)：
-
Osaka University
Graduate School of Dentistry Course for Oral Sciences
Professor
Research field (2)：
Developmental dentistry
, Bacteriology
Research keywords (8)：
Infective endocarditis
, Odontogenic infection
, Pediatric Dentistry
, 全身疾患
, 口腔細菌
, 感染性心内膜炎
, 菌血症
, 小児歯科学
Research theme for competitive and other funds (37)：
- 2024 - 2027 歯周病原性細菌に着目した小児の免疫疾患・感染症の制御に向けた基盤構築
- 2024 - 2027 ミュータンスレンサ球菌による臓器間ネットワークを介した病態の解明と治療戦略の探索
- 2023 - 2026 歯科・腎臓内科コラボレーション:口腔細菌によるIgA腎症発症メカニズムの追求
- 2023 - 2026 S. mutans コラーゲン結合タンパクに着目した IgA 腎症発症機構の解明
- 2022 - 2025 全身疾患との関連性が高いう蝕病原性細菌の定着環境の解明と定着予防法の追究
- 2021 - 2025 う蝕原性細菌のコラーゲン結合能に着目した低中所得国の全身疾患低減に向けた新戦略
- 2021 - 2024 う蝕原性細菌が誘発する全身疾患の制御に向けた新たな病原メカニズムの解明
- 2021 - 2024 小児期のう蝕および口腔内環境に着目したピロリ菌定着の予防法追究に対する新戦略
- 2020 - 2023 Elucidation of the effect of Microorganism of the body on the origin and rupture of the intracranial aneurysms and development of preventive measure of the subarachnoid hemorrhage
- 2020 - 2023 Investigation of the pathogenesis of IgA nephropathy caused by oral bacteria for the development of innovative treatment methods from the field of dentistry.
- 2019 - 2022 Association of dental disease and kidney disease: Examination of oral specimens and renal biopsy / tonsil specimens of IgA nephropathy patients
- 2019 - 2021 A study to elucidate the mechanism of intracerebral heorrhage induced by collagen-binding Streptococcus mutans and to develop a novel preventive therapy
- 2019 - 2021 Role of interorganelle communication in mineralization
- 2018 - 2021 Elucidation of effects of cariogenic bacteria on organ-linked network due to oral barrier breakdown
- 2017 - 2021 Establishment of international liaison between medical doctors and dentists for the purpose of reduction of stroke in Nigeria and Kenya
- 2017 - 2020 Mechanism of aggravation of IgA nephropathy by mutans streptococci
- 2015 - 2019 Clinical investigation of the cerebrovascular diseases aggravation caused by dental caries pathogens and establishing simplified technique for detecting the high risk group.
- 2016 - 2018 Study to understand mechanism of hemorrhagic stroke induced by oral bacteria
- 2015 - 2018 Specification of route of Helicobacter pylori infection and construction of preventive approaches for gastric diseases in pediatric dentistry field
- 2015 - 2018 Construction of global standard molecular epidemiological method for identification of the children at risk for severe dental caries
- 2015 - 2018 Basic and clinical approaches for dental problems associated with skeletal diseases
- 2015 - 2017 Possible involvement of mutans streptococci in development of pediatric kidney disease
- 2015 - 2017 Elucidation of mechanism of non-alcoholic steatohepatitis aggravation caused by mutans streptococci
- 2013 - 2015 Establishment of early screening method for gastric diseases caused by Helicobacter pylori
- 2012 - 2015 Pathogenic mechanism for aggravation of inflammatory bowel diseases caused by oral bacteria and specification of highly virulent strains
- 2012 - 2015 Construction of system in dentistry field to prevent preterm low birth weight delivery
- 2011 - 2014 Investigation of mechanism of systemic diseases caused by oral bacteria and development of preventive procedures
- 2011 - 2013 Study on canine periodontal disease as zoonosis
- 2009 - 2011 Elucidation of mechanism for development of cerebrovascular diseases associated with oral bacteria and pursuit of preventive approach
- 2007 - 2010 Analysis of virulence factors in cariogenic bacteria for cardiovascular diseases
- 2007 - 2008 P.gingivalis線毛遺伝子型の同定と歯周炎発症高リスク者特定への応用
- 2006 - 2008 Molecular biological analyses of virulence factors for infective endocarditis caused by oral streptococci
- 2005 - 2006 感染性心内膜炎動物モデル系の確立と口腔レンサ球菌における病原性の検討
- 2004 - 2006 Molecular analysis of cell surface structures of Streptococcus mutans for virulence of infective endocarditis
- 1996 - Analysis of virulence factors of infective endocarditis caused by oral streptococci
- 1996 - 口腔レンサ球菌による感染性心内膜炎における病原因子の解析
- う蝕原性細菌の全身疾患に関する病原因子の解析
Show all
Papers (466)：
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Ogaya, Y., Kadota, T., Hamada, M., Nomura, R., Nakano, K. Characterization of the unique oral microbiome of children harboring Helicobacter pylori in the oral cavity. Journal of Oral Microbiology. 2024. 16. 1
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Jinthana Lapirattanakul, Ryota Nomura, Rena Okawa, Pornpen Tantivitayakul, Rattiporn Kaypetch, Anna Lehrkinder, Peter Lingström, Dowen Birkhed, Michiyo Matsumoto-Nakano, Kazuhiko Nakano. Multilocus sequence typing and phenotypic properties of Streptococcus mutans from Thai children with different caries statuses. BMC Oral Health. 2024. 24. 1
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Masakazu Hamada, Kyoko Nishiyama, Ryota Nomura, Tatsuya Akitomo, Chieko Mitsuhata, Yoshiaki Yura, Kazuhiko Nakano, Michiyo Matsumoto-Nakano, Narikazu Uzawa, Hiroaki Inaba. Clinical relationships between the intratumoral microbiome and risk factors for head and neck cancer. Heliyon. 2024. 10. 20. e39284
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Shuhei Naka, Daiki Matsuoka, Taro Misaki, Yasuyuki Nagasawa, Seigo Ito, Ryota Nomura, Kazuhiko Nakano, Michiyo Matsumoto-Nakano. Contribution of collagen-binding protein Cnm of Streptococcus mutans to induced IgA nephropathy-like nephritis in rats. Communications biology. 2024. 7. 1. 1141-1141
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Mariko Kametani, Tatsuya Akitomo, Masakazu Hamada, Momoko Usuda, Ami Kaneki, Masashi Ogawa, Shunya Ikeda, Yuya Ito, Shuma Hamaguchi, Satoru Kusaka, et al. Inhibitory Effects of Surface Pre-Reacted Glass Ionomer Filler Eluate on Streptococcus mutans in the Presence of Sucrose. International journal of molecular sciences. 2024. 25. 17
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MISC (387)：
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長澤 康行, 野村 良太, 三崎 太郎, 伊藤 誓悟, 山崎 博充, 庄嶋 健作, 松岡 大貴, 仲 周平, 仲野 道代, 新村 健, et al. IgA腎症患者と習慣性扁桃炎患者の摘出扁桃における歯周病菌の検出率の比較. 日本腎臓学会誌. 2024. 66. 4. 591-591
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伊藤 誓悟, 三崎 太郎, 長澤 康行, 松岡 大貴, 仲 周平, 野村 良太, 仲野 道代, 仲野 和彦. う蝕原性細菌cnm陽性Streptococcus mutansは扁桃を介してIgA腎症を増悪させる. 日本腎臓学会誌. 2024. 66. 4. 637-637
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奥田 真琴, 末廣 雄登, 東條 文和, 又吉 紗綾, 仲 周平, 仲野 道代, 仲野 和彦. 日本人小児口腔におけるStreptococcus mutansの陽性率と齲蝕経験歯数との関連の評価. 小児歯科学雑誌. 2024. 62. 大会抄録号. 120-120
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吉田 翔, 稲葉 裕明, 野村 良太, 仲野 和彦, 仲野 道代. Porphyromonas gulae線毛とバイオフィルム形成能の関連性. 小児歯科学雑誌. 2024. 62. 大会抄録号. 122-122
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東條 文和, 大継 將寿, 仲野 和彦. 小児歯科受診患者における口腔細菌定量分析の実態調査. 小児歯科学雑誌. 2024. 62. 大会抄録号. 124-124
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Education (1)：
- 1990 - 1996 Osaka University School of Dentistry School of Dentistry
Professional career (1)：
Work history (7)：
Awards (5)：
- 2008 - 平成19年度大阪大学教育・研究功績賞
- 2007 - 平成18年度日本小児歯科学会学術賞
- 2007 - 平成18年度大阪大学歯学会優秀研究奨励賞
- 2004 - 第7回大阪大学歯学部弓倉学術奨励賞
- 2003 - 平成14年度日本小児歯科学会奨励賞
Association Membership(s) (5)：
国際歯科研究学会
, 日本小児歯科学会
, 国際小児歯科学会
, 日本小児科学会
, ヨーロッパう蝕学会
