Rchr
J-GLOBAL ID:200901037634037712   Update date: Sep. 01, 2020

Nakanishi Mahito

ナカニシ マヒト | Nakanishi Mahito
Affiliation and department:
Job title: 取締役(技術担当)
Other affiliations (1):
  • ときわバイオ株式会社  つくば研究所長
Homepage URL  (1): http://www.aist.go.jp/RESEARCHERDB/cgi-bin/worker_detail.cgi?call=namae&rw_id=M99191007
Research field  (3): Virology ,  Medical biochemistry ,  Clinical pharmacy
Research keywords  (1): 遺伝子治療 テロメア 細胞不死化 遺伝子導入ベクター センダイウイルス
Research theme for competitive and other funds  (3):
  • 遺伝子治療の基礎技術の開発
  • 1,Gene Transfer through Membrane Fusion 2,Nuclear Targeting of DNA 3,Stabilization of DNA as an artificial chromosome 4,Recombinant Sendai virus vector
  • 1、膜融合を通じた遺伝子導入 2、核への遺伝子ターゲティング 3、核内で安定に存在する人工染色体 4、組換えセンダイウイルスベクター
Papers (95):
  • Tadahiro Honda, Miki Ando, Jun Ando, Midori Ishii, Yumi Sakiyama, Kazuo Ohara, Tokuko Toyota, Manami Ohtaka, Ayako Masuda, Yasuhisa Terao, et al. Sustainable tumor suppressive effect of iPSC-derived rejuvenated T cells targeting cervical cancers. Molecular Therapy. 2020
  • Masaya Tsukamoto, Kazuto Kimura, Miyuu Tanaka, Mitsuru Kuwamura, Manami Ohtaka, Mahito Nakanishi, Kikuya Sugiura, Shingo Hatoya. Generation of Footprint-Free Canine Induced Pluripotent Stem Cells from Peripheral Blood Mononuclear Cells Using Sendai Virus Vector. Molecular reproduction and development. 2020. 87. 6. 663-665
  • Ling Li, Hee Jin Kim, Jee Hoon Roh, Minchul Kim, Wonyoung Koh, Younghoon Kim, Hyohoon Heo, Jaehoon Chung, Mahito Nakanishi, Taeyoung Yoon, et al. Pathological manifestation of the induced pluripotent stem cell-derived cortical neurons from an early-onset Alzheimer's disease patient carrying a presenilin-1 mutation (S170F). Cell proliferation. 2020. 53. 4. e12798
  • Seiji Nagano, Takuya Maeda, Hiroshi Ichise, Soki Kashima, Manami Ohtaka, Mahito Nakanishi, Toshio Kitawaki, Norimitsu Kadowaki, Akifumi Takaori-Kondo, Kyoko Masuda, et al. High Frequency Production of T Cell-Derived iPSC Clones Capable of Generating Potent Cytotoxic T Cells. Molecular therapy. Methods & clinical development. 2020. 16. 126-135
  • Hirokazu Yagi, Maho Yagi-Utsumi, Rena Honda, Yusaku Ohta, Taiki Saito, Miho Nishio, Satoshi Ninagawa, Kousuke Suzuki, Takahiro Anzai, Yukiko Kamiya, et al. Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor. Nature communications. 2020. 11. 1. 1368-1368
more...
MISC (23):
  • Norihiro Ueda, Yasushi Uemura, Rong Zhang, Shuichi Kitayama, Shoichi Iriguchi, Yohei Kawai, Yutaka Yasui, Minako Tatsumi, Tatsuki Ueda, Tian-Yi Liu, et al. Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response. Stem cell reports. 2018. 10. 6. 1935-1946
  • Pablo Menendez, Alvaro Munoz-Lopez, Damia Romer Moya, Cristina Prieto, Veronica Ramos-Mejia, Michela Bardini, Gianni Cazzaniga, Ronald Stam, Agustin Fernandez, Mahito Nakanishi, et al. DEVELOPMENTAL REFRACTORINESS OF MLL-REARRANGED HUMAN ACUTE B-CELL LEUKEMIAS. EXPERIMENTAL HEMATOLOGY. 2016. 44. 9. S40-S40
  • Clara Bueno, Jose Luis Sardina, Damia Romero-Moya, Alvaro Munoz-Lopez, Bruno Di Stefano, Oscar Quintana-Bustamante, Jose Carlos Segovia, Mahito Nakanishi, Thomas Graf, Pablo Menendez. REPROGRAMMING PRIMARY HUMAN MATURE B-CELLS INTO INDUCED PLURIPOTENT STEM CELLS. EXPERIMENTAL HEMATOLOGY. 2015. 43. 9. S80-S80
  • Mahito Nakanishi, Ken Nishimura, Manami Ohtaka, Satoko Takayasu, Masayuki Sano. Development of Defective and Persistent Sendai Virus Vector (SeVdp) and Its Application to Cell Reprogramming. JOURNAL OF GENE MEDICINE. 2014. 16. 7-8. 215-215
  • Dagmar Ogrocki, Jacek Stepniewski, Magdalena Szopa, Neli Kachamakova-Trojanowska, Maciej Matlok, Manami Ohtaka, Mahito Nakanishi, Maciej Malecki, Alicja Jozkowicz, Jozef Dulak. Generation of HNF1A MODY Patient-specific Induced Pluripotent Stem Cells and Their Differentiation Into Insulin-Expressing Cells. DIABETES. 2014. 63. A545-A545
more...
Education (4):
  • Osaka University
  • Osaka University
  • Osaka University
  • Osaka University, Graduate School ,Faculty of Science
Professional career (1):
  • 理学博士 (大阪大学)
Association Membership(s) (5):
Controlled Release Society ,  American Society of Gene Therapy ,  日本癌学会 ,  日本遺伝子治療学会 ,  日本DDS学会
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