Rchr
J-GLOBAL ID:200901037679589210   Update date: Aug. 30, 2020

KUROBE Hirotsugu

クロベ ヒロツグ | KUROBE Hirotsugu
Affiliation and department:
Job title: Associate Professor
Other affiliations (1):
  • Yale University of Medicine, Section of Cardiac Surgery  Visiting Assistant Professor
Homepage URL  (1): http://kaken.nii.ac.jp/ja/r/30380083
Research field  (9): Respiratory surgery ,  Cardiovascular surgery ,  Cardiology ,  General surgery, pediatric surgery ,  Immunology ,  Biomaterials ,  Biomedical engineering ,  Respiratory surgery ,  Cardiovascular surgery
Research keywords  (35): Medical Device ,  Tissue engineering ,  心臓手術 ,  胸腺 ,  細胞性免疫 ,  サイトカイン ,  生活習慣病 ,  慢性炎症 ,  骨髄単核球細胞移植 ,  プラーク ,  動脈硬化 ,  急性冠症候群 ,  細胞治療 ,  肺高血圧治療 ,  自然免疫 ,  肺高血圧 ,  肺高血圧症 ,  循環器 ,  肺動脈再構築 ,  肺小動脈リモデリング ,  リンパ管新生 ,  VEGF-VEGF receptor ,  低酸素応答 ,  小口径グラフト ,  臍帯血 ,  脱細胞化 ,  未熟肺血管床 ,  細胞接着因子 ,  Macrophage ,  T cell ,  Hypoxia inducible factor ,  cell transplantation ,  inflammation ,  Regenerative Medicine ,  Vascular remodeling
Research theme for competitive and other funds  (15):
  • 2020 - 2023 生体吸収性素材を用いた経カテーテル心房中隔閉鎖術の移植後組織再生に関する検討
  • 2015 - 2019 Contributing Factors for Optimal Remodeling of Tissue Engineered Vascular Graft
  • 2016 - 2018 analysis of calcification process in implanted arterial artificial-graft.
  • 2015 - 2018 Clarification of structure-function correlation of silk fibroin for Next Generation Heart Valve
  • 2014 - 2016 Fundamental research for Biodegradable ASD closure system
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Papers (77):
  • 浪口 謙治, 西村 隆, 坂本 裕司, 薦田 宗則, 杉浦 純也, 太田 教隆, 黒部 裕嗣, 打田 俊司, 八杉 巧, 泉谷 裕則. 当院でのIMPELLAを用いた治療経験. 人工臓器. 2019. 48. 2. S-185
  • Cameron A. Best, Jason M. Szafron, Kevin A. Rocco, Jacob Zbinden, Ethan W. Dean, Mark W. Maxfield, Hirotsugu Kurobe, Shuhei Tara, Paul S. Bagi, Brooks V. Udelsman, et al. Differential outcomes of venous and arterial tissue engineered vascular grafts highlight the importance of coupling long-term implantation studies with computational modeling. ACTA BIOMATERIALIA. 2019. 94. 183-194
  • Yohei Kawatani, Hirotsugu Kurobe, Yoshitsugu Nakamura, Takaki Hori. A case of nickel allergy after endovascular aortic repair. Asian cardiovascular & thoracic annals. 2019. 27. 2. 114-117
  • Hiroki Arase, Noriko Sugasawa, Youhei Kawatani, Mikio Sugano, Hirotsugu Kurobe, Eiki Fujimoto, Takashi Kitaichi, Tetsuya Kitagawa. Appropriate Surgical Treatment of Symptomatic Primary Varicose Veins Decreases Systemic Inflammatory Biomarkers. ANNALS OF VASCULAR DISEASES. 2019. 12. 3. 367-371
  • Noriko Sugasawa, Ayako Katagi, Hirotsugu Kurobe, Taisuke Nakayama, Chika Nishio, Hiroko Takumi, Fumiharu Higashiguchi, Ken-ichi Aihara, Michio Shimabukuro, Masataka Sata, et al. Inhibition of Atherosclerotic Plaque Development by Oral Administration of alpha-Glucosyl Hesperidin and Water-Dispersible Hesperetin in Apolipoprotein E Knockout Mice. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION. 2019. 38. 1. 15-22
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MISC (370):
  • 菅野 幹雄, 本間 友佳子, 黒部 裕嗣, 藤本 鋭貴, 北市 隆, 早渕 康信, 北川 哲也. PAIVS、 Ebstein's anomalyに対するone and a half ventricle repair後の重度三尖弁逆流に対して自己心膜による弁尖延長を用いた三尖弁形成が奏功した一例. 日本小児循環器学会雑誌. 2019. 35. Suppl.1. s1-419
  • 北市 隆, 菅野 幹雄, 黒部 裕嗣, 藤本 鋭貴, 本間 友佳子, 早渕 康信, 北川 哲也. 有茎自己心膜を用いた右室流出路再建を行ったVSD/PA症例の遠隔期. 日本心臓血管外科学会学術総会抄録集. 2019. 49回. [PP-018]
  • 黒部 裕嗣, 奥村 早紀, 中山 英隆, 坂元 悠紀, 佐藤 秀樹, 山内 康治, 松崎 雄一, 宮本 真嘉, 宮地 秀樹, 鈴木 昌和, et al. Scaffolds for Regenerative Medicine 生体分解性素材を用いた医療デバイス開発とその現状. 日本バイオマテリアル学会大会予稿集. 2018. 40回. 78-78
  • 菅野 幹雄, 荒瀬 裕己, 川谷 洋平, 黒部 裕嗣, 藤本 鋭貴, 北市 隆, 北川 哲也. 次世代育成プロジェクト2 日本での次世代育成プラン 地方病院の現状から見た小児心臓血管外科診療の将来的展望. 日本小児循環器学会雑誌. 2018. 34. Suppl.1. s1-129
  • 菅野 幹雄, 荒瀬 裕己, 川谷 洋平, 小野 朱美, 黒部 裕嗣, 藤本 鋭貴, 北市 隆, 早渕 康信, 北川 哲也. NCCPによるmoderate ARを伴うVSD閉鎖の術中に緊急大動脈弁形成を要した一例. 日本小児循環器学会雑誌. 2018. 34. Suppl.1. s1-374
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Professional career (2):
  • MD (University of TOKUSHIMA)
  • PhD (University of TOKUSHIMA)
Work history (17):
  • 2019/04 - 現在 Ehime University Graduate School of Medicine Department of Cardiovascular and Thoracic Surgery Associate Professor
  • 2018/04 - 2019/03 Tokushima University Hospital Division of Cardiovascular Surgery Specially Appointed Associate Professor
  • 2013/08 - 2018/03 Tokushima University Graduate School Department of Cardiovascular Surgery, Institute of Biomedical Sciences Assistant Professor
  • 2012/09 - 2013/08 Nationwide Children's Hospital Postdoctoral fellow
  • 2011/07 - 2012/08 Yale University of Medicine Visiting Assistant Professor
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Awards (8):
  • 2011 - Banyu Life Science Foundation International Banyu fellow Ship Program
  • 2010 - Miki Korakukai Foundation Miki-Kouraku Award
  • 2010 - Japanese College of Angiology Excellent presenting Award
  • 2010 - Japanese Association for Thoracic Surgery Plenary session
  • 2005 - School of Medicine, the University of TOKUSHIMA Research award, School of Medicine, the University of TOKUSHIMA
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Association Membership(s) (8):
Japanese society of regenerative medicine ,  Japanese Society of Phlebology ,  JAPANESE CIRCULATION SOCIETY ,  JAPANESE SOCIETY FOR VASCULAR SURGERY ,  THE JAPANESE SOCIETY FOR CARDIOVASCULAR SURGERY ,  THE JAPANESE ASSOCIATION FOR THORACIC SURGERY ,  JAPAN SURGICAL SOCIETY ,  The Society of Thoracic Surgeons
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