Sumizawa Tomoyuki

• 2010 - 肌・皮膚の状態を指標とした栄養・健康状態の評価法の開発
• 2007 - 2008 The mechanism of p53-mediated mitochondrial dysfunction induced by toxic chemicals
• 2000 - 2004 腫瘍増殖・浸潤・転移を抑制する新規薬剤の開発
• 2000 - 2001 Analysis of the mechanisms for biological activities of thymidine phosphorylase
• 1998 - 1999 Physiological function of thymidine phosphorylase and the involvement of the enzyme in tumor growth
1998 - 細胞内小器Vaultの構造と機能に関する研究
1998 - Structure and Function of cell organelle, vault
1997 - 1997 チミジンホスホリラーゼ阻害剤による腫瘍増殖抑制とその基礎的研究
1995 - 1996 Growth and Differentiation through the Cytokine Receptors
1994 - 1995 Structure and function of an active efflux pump for cisplatin
1994 - 1995 The mechanism of regulation of P-glycoprotein (Analysis of multidrug-resistant mutants that do not express P-glycoprotein)
1994 - 1994 P-糖蛋白質の関与しない多剤耐性の機構と、その克服方法の開発
1994 - 1994 エリスロポエチン受容体の情報伝達機構と細胞増殖およびがん化との関連
1994 - 1994 造血幹細胞の増殖を制御するシグナル伝達分子群の解析
1993 - 1994 Structure and Signal Transduction of the Erythropoietin Receptor
1993 - 1994 The mechanism of angiogenesis by PD-ECGF
1993 - 1993 チミジンホスホリラーゼ活性と血管新生の関連性について
1993 - 1993 エリスロポエチン受容体の情報伝達機構と細胞増殖およびがん化との関連
1993 - 1993 サイトカイン受容体の構造と情報伝達機構の分子機序に関する共同研究
1992 - 1992 シスプラチン耐性機構の解析と耐性克服方法の開発
1991 - 1991 Pー糖蛋白質の関与しない多剤耐性の分子機構の解明と克服方法の開発
1990 - 1991 Isolation and analysis of atypical multidrug-resistant mutants.
1990 - 1990 Pー糖蛋白質の構造と機能の研究

• Yusuke Tajitsu, Ryuji Ikeda, Yukihiko Nishizawa, Hirofumi Mataki, Xiao-Fang Che, Tomoyuki Sumizawa, Mina Nitta, Tatsuya Yamaguchi, Masatatsu Yamamoto, Sho Tabata, et al. Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2013. 32. 3. 703-708
• Tanaka Hideaki, Kato Koji, Yamashita Eiki, Sumizawa Tomoyuki, Zhou Yong, Yao Min, Iwasaki Kenji, Yoshimura Masato, Tsukihara Tomitake. 2SJ-05 X-ray structure of the vault, the largest cytoplasmic ribonucleo protein particle(2SJ New developments in protein complex research: From molecules to supramolecules and aggregates,The 49th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri. 2011. 51. S23
• Tanaka H, Kato K, Sumizawa T, Yamashita E. Elucidation of the function based on the whole structure of rat liver vault, the largest ribonucleo-protein particle. Seikagaku. 2011. 83. 5. 392-395
• Ken-ichi Iwashita, Ryuji Ikeda, Yasuo Takeda, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Tatsuya Yamaguchi, Shin-ichi Akiyama, Katsushi Yamada. Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1 alpha and reduces HIF-1 alpha level in ACHN human renal adenocarcinoma cells. CANCER SCIENCE. 2010. 101. 4. 920-926
• 住澤 知之, 加藤 公児, 田中 秀明. 25.ラット肝由来の巨大なRNAタンパク質複合体vaultのX線結晶構造(第27回産業医科大学学会総会 学術講演会記録). 産業医科大学雑誌. 2010. 32. 1. 113-113

ｍore...

• 田中秀明, 加藤公児, 住澤知之, 山下栄樹. 全立体構造決定から切り開く謎の巨大粒子ボルトの機能解明. 生化学. 2011. 83. 5. 392-395
• Shota Takumi, Masaharu Komatsu, Tatsuhiko Furukawa, Ryuji Ikeda, Tomoyuki Sumizawa, Hitomi Akenaga, Yuta Maeda, Kohji Aoyama, Koji Arizono, Seiichi Ando, et al. p53 Plays an Important Role in Cell Fate Determination after Exposure to Microcystin-LR. ENVIRONMENTAL HEALTH PERSPECTIVES. 2010. 118. 9. 1292-1298
• Shota Takumi, Masaharu Komatsu, Tatsuhiko Furukawa, Ryuji Ikeda, Tomoyuki Sumizawa, Hitomi Akenaga, Yuta Maeda, Kohji Aoyama, Koji Arizono, Seiichi Ando, et al. p53 Plays an Important Role in Cell Fate Determination after Exposure to Microcystin-LR. ENVIRONMENTAL HEALTH PERSPECTIVES. 2010. 118. 9. 1292-1298
• 加藤公児, 田中秀明, 山下栄樹, 住澤知之, 周勇, 姚閔, 岩崎憲治, 吉村政人, 月原冨武. 巨大な超分子複合体を見る. 日本蛋白質科学会年会プログラム・要旨集. 2010. 10th. 52
• Ken-ichi Iwashita, Ryuji Ikeda, Yasuo Takeda, Tomoyuki Sumizawa, Tatsuhiko Furukawa, Tatsuya Yamaguchi, Shin-ichi Akiyama, Katsushi Yamada. Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1α and reduces HIF-1α level in ACHN human renal adenocarcinoma cells. Cancer Science. 2010. 101. 4. 920-926

ｍore...

• RNAタンパク質複合体である細胞質オルガネラvaultの構造と機能(分担/共著)
  廣川書店 「生物薬科学実験講座 5 細胞の構造とオルガネラ」 196-208 大熊勝治/中西義信・編集 (住澤知之、秋山伸一) 2010
• 薬剤耐性の分子機構、P-糖蛋白質の関与しない多剤耐性(分担/共著)
  羊土社 1994
• Biomodulation -癌薬物療法の新たな展開-、セファランチン(分担/共著)
  先端医学社 1994
• Cloning and characterization of thymidine phosphorylase, an activating enzyme for pyrimidine antimetabolites. (共著)
  In: T. Miyazaki, F. Takaku and K. Sakurada (eds): The mechanism and new approach on drug resistance of cancer cells. Excerpta Medica, Tokyo 1993
• Cloning and Characterization of thymidine phosphorylase, an activating enzyme for pyrimidine antimetabolites. (Co-author)
  Excerpta Medica(Tokyo)Elsevier Science Publishers 1993

ｍore...

• - 1988 Kyushu University
• - 1988 Kyushu University Graduate School, Division of Agriculture
• - 1983 Kyushu University School of Agriculture
• - 1983 Kyushu University Faculty of Agriculture

• Ph.D.(Medical Science) (Kagoshima University)
• MS (Kyushu University)

• 2010 - 現在 Kagoshima Women's Junior College
• 2005 - 2010 University of Occupational and Environmental Health, Japan
• 2005 - 2010 University of Occupational and Environmental Health,
• 2010 - - Kagoshima Women's Junior College, Professor
• 1997 - 2005 Kagoshima University
1997 - 2005 Kagoshima University, Research Assistant
1995 - 1997 スタンフォード大学 博士研究員
1995 - 1997 Stanford University, Postdoctoral Researcher
1988 - 1995 Kagoshima University
1988 - 1995 Kagoshima University, Research Assistant
Assistant Professor

• 2000 - MBC賞
• 2000 - MBC Award

日本農芸化学会 ,  日本細胞生物学会 ,  日本分子生物学会 ,  日本生化学会 ,  日本癌学会 ,  and Agrochemistry ,  Biotechnology ,  Japan Society for Bioscience ,  Japan Society for Cell Biology ,  The Molecular Biology Society of Japan ,  The Japanese Biochemical Society ,  The Japanese Cancer Association