Kikuta Atsushi

キクタアツシ | Kikuta Atsushi

Affiliation and department：
Job title： Professor

Research field (1)： Hematology and oncology

Research theme for competitive and other funds (4)：

2019 - 2022 The mechanisms of inducing anti-tumor cytotoxic T cells in the tumor immune microenvironment
2016 - 2021 Building up a long-term follow-up system for patients with Pediatric, Adolescent, and Young Adult Thyroid Carcinoma
2015 - 2018 Cancer vaccine with Th1 inducing DC through Notch ligand Dll4
2007 - 2009 molecular analyses and translational research of neuroblastoma based upon a clinical trial of the nation-wide group study

Papers (5)：

Yasuhiro Okamoto, Yozo Nakazawa, Masami Inoue, Kenichiro Watanabe, Hiroaki Goto, Nao Yoshida, Maiko Noguchi, Atsushi Kikuta, Koji Kato, Yoshiko Hashii, et al. Hematopoietic stem cell transplantation in children and adolescents with nonremission acute lymphoblastic leukemia. Pediatric blood & cancer. 2020. 67. 12. e28732
Kimikazu Yakushijin, Takayuki Ikezoe, Chikako Ohwada, Kazuko Kudo, Hiroshi Okamura, Hiroaki Goto, Hiromasa Yabe, Atsushi Yasumoto, Hideyuki Kuwabara, Shiro Fujii, et al. Clinical effects of recombinant thrombomodulin and defibrotide on sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation. Bone marrow transplantation. 2019. 54. 5. 674-680
Kazuo Umemura, Takayuki Iwaki, Toshimi Kimura, Chitose Ogawa, Takahiro Fukuda, Shuichi Taniguchi, Keizo Horibe, Hiroaki Goto, Kenichi Yoshimura, Yasutaka Watanabe, et al. Pharmacokinetics and Safety of Defibrotide in Healthy Japanese Subjects. Clinical pharmacology in drug development. 2016. 5. 6. 548-551
Yasuo Horikoshi, Ryoji Kobayashi, Mikiya Endo, Arata Watanabe, Atsushi Kikuta, Kazutoshi Koike, Ryoji Hanada, Ryota Hosoya, Akira Ohara, Koichiro Ikuta, et al. [Effectiveness of remission induction with high-dose cytarabine for relapsed or refractory pediatric acute leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2010. 51. 2. 104-13
Takao Yoshihara, Keiko Okada, Michihiro Kobayashi, Atsushi Kikuta, Koji Kato, Naoto Adachi, Akira Kikuchi, Hiroyuki Ishida, Yasuzou Hirota, Hiroshi Kuroda, et al. Outcome of non-T-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation from family donors in children and adolescents. International journal of hematology. 2007. 85. 3. 246-55

MISC (2)：

Hiroyuki Fujisaki, Yoshiko Hashii, Keita Terashima, Hiroaki Goto, Keizo Horibe, Kazuhiko Sugiyama, Akinobu Watanabe, Saori Sugimoto, Takaaki Yanagisawa, Atsushi Kikuta, et al. PHASE 1/2 STUDY OF DSP-7888 IN PEDIATRIC PATIENTS WITH MALIGNANT GLIOMA. NEURO-ONCOLOGY. 2018. 20. 202-202
Chitose Ogawa, Atsushi Manabe, Hiroaki Goto, Katsuyoshi Koh, Daisuke Tomizawa, Keitaro Fukushima, Ken-ichiro Watanabe, Keizo Horibe, Atsushi Kikuta, Mitsuma Hamada, et al. Phase I/II Clinical Trial of Erwinia Asparaginase (Erwinase(R)) in Combination with Prednisolone, Vincristine and Pirarubicin in Children and Young Adults with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL). BLOOD. 2014. 124. 21

Lectures and oral presentations (1)：

Ex vivo-activated allogeneic CD4+ T-cells disrupt immunosuppressive tumor microenvironment, and induce host tumor-specific cytotoxic T-cells in mice
(34th Annual Meeting & Pre-Conference Programs(SITC 2019), National Harbor, 2019)

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