Research theme for competitive and other funds (19):
2023 - 2027 Development of Partially Regenerated Heart Valves Based on Silk Fibroin for Clinical Application
2022 - 2025 血管内腔側から徐々に吸収される階層構造を持つ生体吸収性動脈グラフトの開発
2021 - 2023 シルクフィブロインとカイコ蛹の機能性に基づく次世代型シルク産業の創出
2020 - 2023 脂肪組織由来の間質血管細胞群を用いた静脈用シルクフィブロイン人工血管の開発
2020 - 2023 理想的な血管再生を誘導する多層性動脈グラフトの創製
2021 - 2022 シルクフィブロイン複合用ポリウレタンの医療材料基礎研究
2020 - 2022 心臓血管系修復材を構成する新規素材の創製と心臓修復パッチへの応用
2019 - 2022 The development of bioresorbable arterial graft that promote the vascular remodeling by macrophage infiltration from the outside of the graft
2018 - 2021 Prevention of postoperative atrial fibrillation after cardiac surgery by an innovative inflammatory drug elution system
2015 - 2018 Clarification of structure-function correlation of silk fibroin for Next Generation Heart Valve
2014 - 2018 Development of novel analytical NMR system for regenerative medical materials and its application for silk artificial vascular grafts
2014 - 2017 Development of a new expandable sheet for surgical correction of pediatric cardiac disorders by biodegradation and inducing tissue restoration.
2011 - 2015 Determination of Inter-molecular Structures of Fibers and Polymers using Ultra-High Field Solid State NMR with Ultra-High Speed NMR Probe
2011 - 2015 Development of silk fibroin-polyurethane composite material for small diameter vascular graft
2008 - 2009 Development of chimeric protein based on the silk fibroin and high calcium binding motifs for bone regeneration.
2004 - 2006 固体NMRによる精密構造構築手法の開発とアミロイド線維化機構解明への応用
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Papers (105):
Hideki Miyachi, Shuhei Tara, Hidetaka Nakayama, Rikako Hama, Tadahisa Sugiura, James W Reinhardt, Tai Yi, Yong-Ung Lee, Avione Y Lee, Shinka Miyamoto, et al. Transmural macrophage migration into an arterial bioresorbable vascular graft promotes inflammatory-mediated response and collagen deposition for vascular remodeling. Acta biomaterialia. 2024
Tetsuo Asakura, Haruka Shimokawatoko, Yasumoto Nakazawa. Characterization and promotion of endothelialization of Bombyx mori silk fibroin functionalized with REDV peptide. International Journal of Biological Macromolecules. 2024. 261. 129746-129746
Rikako Hama, Yasumoto Nakazawa. Evaluation of the Modification Effects of Heparin/Dalteparin on Silk Fibroin Structure and Physical Properties for Skin Wound Healing. Polymers. 2024. 16. 3. 321-321
Hussein Elhusseiny, Eman Mady, Masahiro Kaneda, Kazumi Shimada, Yasumoto Nakazawa, Tatsuya Usui, Mohamed Elbadawy, Yusuke Ishihara, Moeko Hirose, Yohei Kamei, et al. Comparison of bovine- and porcine-derived decellularized biomaterials: Promising platforms for tissue engineering applications. Pharmaceutics. 2023
Rikako Hama, Derya Aytemiz, Kelvin O Moseti, Tsunenori Kameda, Yasumoto Nakazawa. Silk Fibroin Conjugated with Heparin Promotes Epithelialization and Wound Healing. Polymers. 2022. 14. 17. 3582
Nakazawa, Y, Honda, T, Ibe, Y, Jono, T. Development of Tissue Engineering Materials by Silk Fibroin-Biodegradable Polyurethane Composites. 2022. 66. 3-10
Nakazawa, Y. Introduction of “Medical Materials Research Committee. 2022. 78. 6. 230-231
YASUMOTO NAKAZAWA. Development of New Functional Silk Fibroin Materials for the Regenerative Medicine. Sen'i Gakkaishi. 2021. 77. 8. 396-400
TETSUO ASAKURA, YASUMOTO NAKAZAWA. Nature and Science Museum, Tokyo University of Agriculture and Technology. Sen'i Gakkaishi. 2021. 77. 3. 126-129
プラスチック成型加工学会
, THE SOCIETY OF FIBER SCIENCE AND TECHNOLOGY
, 日本核磁気共鳴学会
, THE SOCIETY OF POLYMER SCIENCE
, 日本人工臓器学会
, 日本炎症再生医学会
, THE JAPANESE SOCIETY FOR BIOMATERIALS
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE