Research theme for competitive and other funds (50)：
2022 - 2025 Molecular mechanism and its physiological significance of metal coordination in Tyrosinase family proteins
2021 - 2024 Development of a rapid gamete production technique using germ cell transplantation into a gonad of germ cell-less fish.
2020 - 2023 in vivo MR顕微鏡による細胞レベルラジオミクス
2019 - 2023 WHERE DID GAMETE DUCTS OF TELEOSTS COME FROM?
2018 - 2023 Uncovering the secrets of lipid-transporting ABC proteins
2017 - 2023 噛み合い防除のため切歯形成遺伝子を多重低機能化したトラフグ切歯の形態解析
2019 - 2022 Generation of "infertile fish" to prevent genetic pollution and development of its mass production technology
2017 - 2021 Development of the fish pathogenic bacterial infection prevention technique utilizing the polysaccharide recognition mechanism derived from pathogenic bacteria
2017 - 2020 Individual time-series visualization of human disease models of small fish by in vivo 14.1 T MR microscopy
2017 - 2020 Genome Editing without microinjection into eggs
2016 - 2019 Development of efficient delivery method for genome editing in aquaculture fish
2015 - 2019 Exploring the functions of leptin in fish
2015 - 2019 Search for cell-cell interactions during ovarian development through inhibition of oocyte differentiation
2015 - 2018 Model cell-line and model animals of MIRAGE syndrome
2015 - 2018 Unveiling the Pathological Mechanisms and Developing New Treatment of Parkinsons Disease Caused by GBA1 Mutations
2015 - 2017 Genetic research on Parkinson's disease using medaka fish
2014 - 2017 Development of basic technology for production of tiger pufferfish with low teeth formation to prevent mutual bite.
2014 - 2017 Development of new aquaculture using designated nuclease
2014 - 2017 Molecular basis fo protein-crosslinking reaction by transglutaminase focusing on aberrant regulation
2012 - 2015 Establishment of Molecular Genetic Method for Damage-response at Tissue Cell
2011 - 2015 Study on the mechanisms regulating fate specification of pigment cell subtypes
2011 - 2014 A study on mechanism of tetrodotoxin poisoning in tiger pufferfish by binding protein
2008 - 2011 Screening of sex differentiation factors using female-gamete labeled fish
2007 - 2009 海産魚における生殖細胞ゲノムへのインテグレートを目指した遺伝子導入法の開発
2007 - 2008 メダカ卵形成の開始を指標に性分化過程を解析する
2004 - 2008 Establishment of Neuroglycobiol ogy (Glycobiological Approach for Neuroscience)
2005 - 2006 メダカ卵形成開始機構の解析から性分化の分子カスケードへ迫る
2004 - 2006 The novel pathway of melanosis on crustaceans and its prevention.
2004 - 2006 Visualization of water pollutant using transgenic medaka
2003 - 2005 Studies on the post-mortem fish muscle tenderization -Analysis using the transgenic red seabream
1999 - 2003 DEVELOPMENT OF INTRODUCTION OF TRANSGENE INTO MEDAKA EGGS AND MANUPILATION OF GENE EXPRESION
2000 - 2002 魚類初期発生に関する研究
2000 - 2002 Studies on taste, flavor and their development of fish meat
2001 - 2001 魚類におけるトリメチルアミンオキシドの起源と生合成機構に関する研究
2000 - 2001 STUDY OF REGULATORY REGION OF FISH TIMP GENE
2000 - 2001 Developmental analyzes of primordial-germ cells and induction of germ-line chimera in fish
1998 - 1999 魚類における前駆体型コラーゲン分解酵素の活性化機構に関する研究
1998 - 1999 Development of mass production system of fish gonadotropin using transgenic fish.
1997 - 1998 Analysis on Ayu. Muscle collagenases induced in the spawning stage
1995 - 1997 Studies on developing the non-destructive method for freshness assessment of fish and shellfish.
1995 - 1996 Studies on fibronectin-like protein of Japanese flounder
1995 - 1995 魚類変態期におけるメタロチオネインの機能に関する研究
1994 - 1995 Studies on Flavor and Texture of Live Fish Meat
遺伝子導入メダカを用いた環境評価
日本産アカウミガメの母浜回帰に関する研究
トランスジェニックフィッシュの開発
Assesment of water pollutant using transgenic medaka
Study on homing ofJapanese logger head turtle
Production of transgenic fish
Study on developmental biology of fish
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Papers (193)：
Hiroyuki Yoshikawa, Yasuko Ino, Kenta Kishimoto, Masato Kinoshita, Yasutoshi Yoshiura. Efficient production of donor-derived tiger puffer gametes from grass puffer recipient with germ cell deficiency by CRISPR-Cas9 mediated knockout of dead end 1. Aquaculture. 2025. 595. 741626-741626
Sakuto Yamanaka, Mari Kawaguchi, Shigeki Yasumasu, Kenji Sato, Masato Kinoshita. Effects of Light and Water Agitation on Hatching Processes in False Clownfish Amphiprion ocellaris. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 2024
Yu Murakami, Masashi Ando, Kenta Kishimoto, Mitsuki Ohama, Yuto Uemura, Reoto Tani, Atsushi Akazawa, Kentaro Matsumiya, Kenji Sato, Masato Kinoshita. Alterations in the fillet quality of myostatin-knockout red sea bream Pagrus major: Preliminary insights into nutritional, compositional, and textural properties. Heliyon. 2024. 10. 11. e32242-e32242
Shintaro Sakaki, Reo Ito, Hideki Abe, Masato Kinoshita, Eiichi Hondo, Atsuo Iida. Electric organ discharge from electric eel facilitates DNA transformation into teleost larvae in laboratory conditions. PeerJ. 2023. 11. e16596-e16596
Akira Kanamori, Ryota Kitani, Atsuko Oota, Koudai Hirano, Taijun Myosho, Tohru Kobayashi, Kouichi Kawamura, Naoyuki Kato, Satoshi Ansai, Masato Kinoshita. Wnt4a Is Indispensable for Genital Duct Elongation but Not for Gonadal Sex Differentiation in the Medaka, Oryzias latipes. Zoological science. 2023. 40. 5. 348-359
An attempt to detect contamination with estrogenic compounds in Thailand and Malaysia using transgenic medaka
(the 2nd International Symposium of Oryzias fish; Small fish with Big Potentials 2009)
科学研究のモデル生物としてのユニークなメダカ
(第10回全国めだかシンポジウム 2008)
Education (2)：
- 1991 Kyoto University
- 1991 Kyoto University Graduate School, Division of Fisheries
