Rchr
J-GLOBAL ID:200901038632132439   Update date: Nov. 26, 2019

NISHI RYOTARO

ニシ リョウタロウ | NISHI RYOTARO
Affiliation and department:
Job title: Assistant Professor
Research field  (4): Molecular biology ,  Cell biology ,  Genetics/Chromosome dynamics ,  Radiation science
Research keywords  (1): DNA repair, DNA double-strand breaks, ubiquitylation, deubiquitylation
Research theme for competitive and other funds  (1):
  • 2012 - 2015 Identifying and characterizing deubiquitylating enzymes that control cellular responses to DNA double-strand breaks
Papers (14):
  • Mayu Isono, Atsuko Niimi, Takahiro Oike, Yoshihiko Hagiwara, Hiro Sato, Ryota Sekine, Yukari Yoshida, Shin-Ya Isobe, Chikashi Obuse, Ryotaro Nishi, Elena Petricci, Shinichiro Nakada, Takashi Nakano and Atsushi Shibata. BRCA1 directs the repair pathway to homologous recombination by promoting 53BP1 dephosphorylation. Cell Reports. 2017. 18. 520-532
  • Paul Wijnhoven, Rebecca Konietzny, Andrew N. Blackford, Jonathan Travers, Benedikt M. Kessler, Ryotaro Nishi* and Stephen P. Jackson*. USP4 Auto-Deubiquitylation Promotes Homologous Recombination. Molecular Cell. 2015. 60. 362-373
  •  Masaki Akita, Yon-Soo Tak, Tsutomu shimura, Syota Matsumoto, Yuki Okuda-Shimizu, Yuichiro Shimizu, Ryotaro Nishi, Hisato Saitoh, Shigenori Iwai, Toshio Mori, Tsuyoshi Ikura, Wataru Sakai, Fumio Hanaoka and Kaoru Sugasawa. SUMOylation of xeroderma pigmentosum group C protein regulates DNA damage recognition during nucleotide excision repair. SCIENTIFIC REPORTS. 2015. 5. 1-12
  • Syota Matsumoto, Eric S. Fisher, Takeshi Yasuda, Naoshi Dohmae, Shigenori Iwai, Toshio Mori, Ryotaro Nishi, Ken-ichi Yoshino, Wataru Sakai, Fumio Hanaoka, Nicolas H, Thomä and Kaoru Sugasawa. Functional regulation of the DNA damage-recognition factor DDB2 by ubiquitination and interaction with xeroderma pigmentosum group C protein. Nucleic Acids Research. 2015. 43. 3. 1700-1713
  • Ryotaro Nishi, Paul Wijnhoven, Carlos le Sage, Jorrit Tjeertes, Yaron Galanty, Josep V. Forment, Michael J. Clague, Sylvie Urbé and Stephen P Jackson. Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity. Nature Cell Biology. 2014. 16. 1016-1026
more...
Lectures and oral presentations  (27):
  • ゲノム損傷修復因子のin vivoダイナミクスとその制御機構
    (バイオアーキテクトシンポジウム 2007)
  • ヌクレオチド除去修復因子の細胞内動態とその制御機構の解析
    (第30回 日本分子生物学会年会・第80回 日本生化学会大会 2007)
  • ヌクレオチド除去修復因子の細胞内動態とその制御機構
    (第19回 DNA複製・分配ワークショップ・合同ワークショップ 2008)
  • Centrin 2 enhances in vitro nucleotide excision repair via complex formation with xeroderma pigmentosum group C pretein through its C-terminal domain
    (The 31st Annual Meeting of the Molecular Biology Society of Japan 2008)
  • Centrin 2 は損傷認識因子XPCとDDB2の相互作用を促進する
    (3Rワークショップ 2009)
more...
Education (3):
  • - 2001 Tokyo University of Science Faculty of Pharmaceutical Sciences Department of Pharmaceutics
  • - 2003 Nara Institute of Science and Technology Graduate School of Biological Science
  • - 2006 Osaka University Graduate School, Division of Pharmaceutical Sciences Applied Pharmacy and Biomedicinal Sciences Major
Professional career (1):
  • Ph.D. (Pharmaceutical Sciences) (Osaka University)
Work history (1):
  • 2010/06/05 - 2015/03/31 The Gurdon Institute, University of Cambridge, Post-doctoral fellow
Awards (1):
  • 2015/10 - 放射線影響学会ワークショップ 放射線影響学会ワークショップ優秀発表賞
Association Membership(s) (3):
The Molecular Biology Society of Japan ,  Japan Society for Cell Biology ,  JAPANESE CANCER ASSOCIATION
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