NISHI RYOTARO

ニシリョウタロウ | NISHI RYOTARO

Affiliation and department：
Job title：准教授

Research field (4)： Radiology , Genetics , Cell biology , Molecular biology

Research keywords (1)： DNA repair, DNA double-strand breaks, ubiquitylation, deubiquitylation

Research theme for competitive and other funds (5)：

2016 - 2020 核内構造体によるDNA二重鎖切断修復制御機構の解明
2015 - 2016 新規nuclear speckle因子USP42によるDNA修復制御機構の解明
2012 - 2015 Identifying and characterizing deubiquitylating enzymes that control cellular responses to DNA double-strand breaks
2008 - 2011 Studies on novel molecular mechanisms that regulate repair of genomic DNA damage caused by environmental stresses
2007 - 2009 Crosstalk between cell cycle regulatory mechanism and DNA repair

Papers (18)：

Misaki Matsui, Ryo Sakasai, Masako Abe, Yusuke Kimura, Shoki Kajita, Wakana Torii, Yoko Katsuki, Masamichi Ishiai, Kuniyoshi Iwabuchi, Minoru Takata, et al. USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA-RNA helicase DHX9. Oncogenesis. 2020. 9. 6. 60-60
Ryotaro Nishi, Paul W G Wijnhoven, Yusuke Kimura, Misaki Matsui, Rebecca Konietzny, Qian Wu, Keisuke Nakamura, Tom L Blundell, Benedikt M Kessler. The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage. Scientific reports. 2018. 8. 1. 17891-17891
Ryotaro Nishi. Balancing act: To be, or not to be ubiquitylated. Mutation research. 2017. 803-805. 43-50
Nakamura,T, Murakami,K, Tada,H, Uehara,Y, Nogami,J, Maehara,K, Ohkawa,Y, Saitoh,H, Nishitani,H, Ono,T, et al. Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair-dependent and independent mechanisms. Genes Cells. 2017. 22. 4. 392-405
Mayu Isono, Atsuko Niimi, Takahiro Oike, Yoshihiko Hagiwara, Hiro Sato, Ryota Sekine, Yukari Yoshida, Shin-Ya Isobe, Chikashi Obuse, Ryotaro Nishi, et al. BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation. CELL REPORTS. 2017. 18. 2. 520-532

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MISC (4)：

松本翔太, 安田武嗣, 堂前直, 村上浩一, 西良太郎, 花岡文雄, 菅澤薫. DNA損傷認識蛋白質DDB2のN末端領域の機能解析(Functional analysis of the N-terminal domain of the DNA damage recognition protein DDB2). 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2010. 83回・33回. 1T12-9
菅澤薫, 志村勉, 赤木純一, 西良太郎. ヌクレオチド除去修復における損傷認識とユビキチン化. 生化学. 2007. 3W23-3
安田武嗣, 菅沢薫, 清水祐一郎, 西良太郎, 岩井成憲, 塩見忠博, 花岡文雄. XPC複合体およびUV-DDBの損傷DNA結合活性に対するヌクレオソーム構造の影響. 日本分子生物学会年会プログラム・講演要旨集. 2004. 27th. 637
Kaoru Sugasawa, Ryotaro Nishi, Yuki Okuda, Toshio Mori, Fumio Hanaoka. Functional analysis of centrin2 in XPC protein complex. CELL STRUCTURE AND FUNCTION. 2004. 29. 63-63

Lectures and oral presentations (41)：

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Education (3)：

Professional career (1)：

Work history (5)：

2020/04 - 現在 Tokyo University of Technology School of Bioscience and Biotechnology Associate Professor
2015/04 - 2020/03 Ritsumeikan University College of Llife Science Department of Biomedical Sciences Assistant Professor
2010/06/05 - 2015/03/31 The Gurdon Institute, University of Cambridge, Post-doctoral fellow
2007/04/01 - 2010/03/31 国立大学法人神戸大学自然科学系先端融合研究環バイオシグナル研究センター、助教
2006/04/01 - 2007/03/31 理化学研究所、基礎科学特別研究員

Awards (3)：

Association Membership(s) (4)：

日本放射線影響学会 , JAPANESE CANCER ASSOCIATION , Japan Society for Cell Biology , The Molecular Biology Society of Japan

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