Research theme for competitive and other funds (17):
2022 - 2025 頭頸部扁平上皮癌の神経周囲浸潤:ゲノム編集を用いた腫瘍生物学的解析
2020 - 2023 Bookmarking function of p63, a nuclear marker of oral carcinomas
2019 - 2022 Chromatin remodeling in malignant progression of head-and-neck squamous cell carcinomas
2015 - 2020 Protecting healthcare workers from imported and emerging infectious diseases! Research on protective equipment for formulating clinical site guideline.
2015 - 2018 Genome editing for p63 in a head-and-neck squamous carcinoma cell line
2013 - 2016 Functions of p63 exoressed in hepatocellular carcinoma: DNA damage responses and relation to virus-induced carcinogenesis
2012 - 2015 Activation of Wnt/beta-catenin signaling by the loss of p63 in malignant oral cancers
2009 - 2011 Phosphoprotein array analyses for determination of signaling pathways activated by p63 in squamous cell carcinomas
Yang XY, Ozawa S, Kato Y, Maehata Y, Izukuri K, Ikoma T, Kanamori K, Akasaka T, Suzuki K, Iwabuchi H, et al. C-X-C Motif Chemokine Ligand 14 is a Unique Multifunctional Regulator of Tumor Progression. International journal of molecular sciences. 2019. 20. 8
Growth suppression of carcinoma cells by p51/p63-silencing
(2007 AACR Annual Meeting 2007)
SMAD3 regulates ΔN type transcription of p51/p63 in carcinoma cells
(American Association for Cancer Reserach 97th Annual Meeting 2006)
Apaf-1 is not essential for initiator caspase-9 activation in apoptosis by physiological stresses.
(20th IUBMB (International Congress of Biochemistry and Molecular Biology) 2006)
p51/p63 induces secretory adhesion protein MFG-E8 in epithelial cells.
(American Association for Cancer Research 96th Annual Meeting, 2005)
p51/p63 promotes lactadherin (MFG-E8) expression in epithelia.
(The 54th Montagna Symposium on the Biology of Skin 2005)