Rchr
J-GLOBAL ID:200901038829846867   Update date: Jul. 09, 2024

Obara Keisuke

オバラ ケイスケ | Obara Keisuke
Affiliation and department:
Job title: Lecturer
Research field  (3): Cell biology ,  Functional biochemistry ,  Molecular biology
Research keywords  (3): Biomembrane ,  Plasma membrane ,  Proteolysis
Research theme for competitive and other funds  (24):
  • 2022 - 2025 細胞膜との相互作用を介した脂質非対称センシングの分子機構
  • 2022 - 2024 真菌感染症の予防を目指した脂質非対称シグナル伝達機構の解明
  • 2019 - 2022 Sensing mechanism and signal output of plasma membrane lipid asymmetry
  • 2020 - 2022 脂質非対称バイオセンサーの開発を通した生体膜研究のボトルネック解消と細胞外物理化学変数の感知機構に関する新奇概念の提唱
  • 2018 - 2020 Development of a lipid asymmetry biosensor that dramatically facilitates studies on biomembranes
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Papers (51):
  • Yoshitaka Ogawa, Taisei P Ueda, Keisuke Obara, Kohei Nishimura, Takumi Kamura. A Single-step Generation of AlissAID-based Conditional Knockdown Strains Using Nanobody that Targets GFP or mCherry in Budding Yeast. Bio-protocol. 2024. 14. 12. e5019
  • Keisuke Obara, Kohei Nishimura, Takumi Kamura. E3 Ligases Regulate Organelle Inheritance in Yeast. Cells. 2024. 13. 4
  • Yoshitaka Ogawa, Taisei P Ueda, Keisuke Obara, Kohei Nishimura, Takumi Kamura. Targeted Protein Degradation Systems: Controlling Protein Stability Using E3 Ubiquitin Ligases in Eukaryotic Species. Cells. 2024. 13. 2
  • Yoshitaka Ogawa, Kohei Nishimura, Keisuke Obara, Takumi Kamura. Development of AlissAID system targeting GFP or mCherry fusion protein. PLoS genetics. 2023. 19. 6. e1010731
  • Kanako Bessho-Uehara, Kengo Masuda, Diane R Wang, Rosalyn B Angeles-Shim, Keisuke Obara, Keisuke Nagai, Riri Murase, Shin-Ichiro Aoki, Tomoyuki Furuta, Kotaro Miura, et al. Regulator of Awn Elongation 3, an E3 ubiquitin ligase, is responsible for loss of awns during African rice domestication. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 4. e2207105120
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MISC (43):
  • Francisco Piña, Fumi Yagisawa, Keisuke Obara, J D Gregerson, Akio Kihara, Maho Niwa. Sphingolipids activate the endoplasmic reticulum stress surveillance pathway. The Journal of cell biology. 2018. 217. 2. 495-505
  • 山口 竜, 中務 邦雄, 奥村 文彦, 小原 圭介, 嘉村 巧. 出芽酵母E3リガーゼSCFMet30によるAry34の分解制御機構の解析. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-0186]
  • 藤澤 宗隆, 中務 邦雄, 小原 圭介, 奥村 文彦, 嘉村 巧. 出芽酵母トリアシルグリセロールリパーゼの制御メカニズムの解析. 生命科学系学会合同年次大会. 2017. 2017年度. [2P-0145]
  • 鈴木 優太, 中務 邦雄, 小原 圭介, 奥村 文彦, 嘉村 巧. リボソーム生合成を負に制御するDot6とTod6は飢餓条件においてプロテアソーム依存的に分解される. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-0190]
  • Farzan Ghanegolmohammadi, Mitsunori Yoshida, Shinsuke Ohnuki, Yuko Sukegawa, Hiroki Okada, Keisuke Obara, Akio Kihara, Kuninori Suzuki, Tetsuya Kojima, Nozomu Yachie, et al. Systematic analysis of Ca2+ homeostasis in Saccharomyces cerevisiae based on chemical-genetic interaction profiles. Molecular biology of the cell. 2017. 28. 23. 3415-3427
more...
Books (1):
  • Programmed cell death in xylem differentiation.
    Programmed cell death in plants (J. Gray eds.), Sheffield Academic Press 2003
Works (2):
  • 生化学辞典第4版
    2007 -
  • 植物の生化学・分子生物学
    2005 -
Education (2):
  • 1999 - 2004 The University of Tokyo Graduate School, Division of Science
  • 1995 - 1999 The University of Tokyo Faculty of Science
Professional career (1):
  • 博士(理学) (東京大学)
Work history (4):
  • 2022/07 - 現在 Nagoya University Graduate School of Science Lecturer
  • 2017/07 - 2022/06 Graduate School of Science, Nagoya University Assistant Professor
  • 2008/05/16 - 2017/06/30 Hokkaido University Faculty of Pharmaceutical Sciences Assistant professor
  • 2004/04/01 - 2008/05/15 National Institute for Basic Biology Postdoctoral fellow
Committee career (10):
  • 2008 - 現在 Engaged in research on sensing mechanism of lipid asymmetry in the plasma membrane
  • 2008 - 現在 Engaged in research on function of sphingolipids at molecular/cellular level
  • 2008 - 現在 細胞膜脂質非対称センシング機能の研究に従事
  • 2008 - 現在 分子・細胞レベルでのスフィンゴ脂質の機能の研究に従事
  • 2004 - 2008 オートファゴソーム形成機構の研究に従事
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Awards (1):
  • 2013/06/20 - 日本細胞生物学会 日本細胞生物学会若手最優秀発表賞
Association Membership(s) (5):
Japanease Society for Ceramides ,  Yeast Genetics Society of Japan ,  Japan Society for Cell Biology ,  The Japanease Biochemical Society ,  The Molecular Biology Society of Japan
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