Rchr
J-GLOBAL ID:200901038883989959   Update date: Mar. 04, 2024

Ohno Hiroshi

オオノ ヒロシ | Ohno Hiroshi
Affiliation and department:
Job title: チームリーダー
Research theme for competitive and other funds  (52):
  • 2022 - 2025 宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究
  • 2019 - 2023 腸炎における粘膜障害治癒に関与する腸内細菌の同定とそのメカニズムの解明
  • 2019 - 2022 The impact of gut microbiota on autoimmune diseases
  • 2018 - 2021 Elucidation of oral-gut association based on Elucidation of oral-gut association based on multi-omics analyzes
  • 2016 - 2019 Differentiation and function of M cells, a unique intestinal epithelial cell subset for untigen uptake
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Papers (254):
  • Kayo Ito, Hirokuni Miyamoto, Makiko Matsuura, Chitose Ishii, Yumiko Nakanishi, Wataru Suda, Takashi Satoh, Fuyuko Honda, Atsushi Kurotani, Naoko Tsuji, et al. A thermoprotective probiotic function by thermostable lactic acid bacteria and its causal structure. Journal of Functional Foods. 2024. 113. 106001-106001
  • Shino Nemoto, Tetsuya Kubota, Tomoyuki Ishikura, Manabu Nakayama, Atsuo Kobayashi, Junshi Yazaki, Kazuyo Uchida, Masashi Matsuda, Takashi Kondo, Osamu Ohara, et al. Characterization of metabolic phenotypes and distinctive genes in mice with low-weight gain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024. 38. 1. e23339
  • Tadashi Takeuchi, Tetsuya Kubota, Yumiko Nakanishi, Hiroshi Tsugawa, Wataru Suda, Andrew Tae-Jun Kwon, Junshi Yazaki, Kazutaka Ikeda, Shino Nemoto, Yoshiki Mochizuki, et al. Gut microbial carbohydrate metabolism contributes to insulin resistance. Nature. 2023. 621. 7978. 389-395
  • Hiroshi Mori, Tamotsu Kato, Hiroaki Ozawa, Mitsuo Sakamoto, Takumi Murakami, Todd D Taylor, Atsushi Toyoda, Moriya Ohkuma, Ken Kurokawa, Hiroshi Ohno. Assessment of metagenomic workflows using a newly constructed human gut microbiome mock community. DNA research : an international journal for rapid publication of reports on genes and genomes. 2023. 30. 3
  • Miyamoto H, Ito K, Honda F, Matsuura M, Ishii C, Tsuji N, Nakaguma T, Ito T, Suda W, Shindo C, et al. Weizmannia coagulans functions as a heat-stress protective probiotic via modulation of the pyridoxal-oxalate interaction. 2023
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MISC (173):
  • Tadashi Takeuchi, Yumiko Nakanishi, Kazutaka Ikeda, Hiroshi Tsugawa, Wataru Suda, Yoshiko Mizuno, Nobutake Yamamichi, Makoto Arita, Masahira Hattori, Naoto Kubota, et al. Gut Microbial Fermentation of Polysaccharides Impacts Insulin Resistance in Humans. DIABETES. 2020. 69
  • 山崎恭子, 山崎恭子, 中島麻由佳, 竹内麻衣, 原実生, 都野隆博, 都野隆博, 松岸葵, 松岸葵, 松川由実, et al. Periodontal disease exacerbates NAFLD via dysbiosis of gut microbiota. 腸内細菌学雑誌. 2020. 34. 2
  • Mari Tenno, Alicia Yoke Wei Wong, Mika Ikegaya, Eiji Miyauchi, Wooseok Seo, Peter See, Tamotsu Kato, Takashi Taida, Michiko Oishi-Ohno, Hiroshi Ohno, et al. Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells. Life Science Alliance. 2020. 3. 1
  • 中西 裕美子, 竹内 直志, 水野 由子, 山道 信毅, 須田 亙, 服部 正平, 窪田 直人, 窪田 哲也, 大野 博司. 2型糖尿病や肥満の発症に関わる腸内細菌と代謝物の探索. 糖尿病. 2019. 62. Suppl.1. S-218
  • 中西裕美子, 中西裕美子, 竹内直志, 水野由子, 山道信毅, 須田亙, 服部正平, 服部正平, 窪田直人, 窪田直人, et al. 2型糖尿病や肥満の発症に関わる腸内細菌と代謝物の探索. 糖尿病(Web). 2019. 62. Suppl
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Patents (1):
  • m3B遺伝子欠損非ヒト動物
Education (2):
  • 1987 - 1991 Chiba University Graduate School of Medicine
  • 1977 - 1983 Chiba University School of Medicine
Professional career (1):
  • 医学博士
Work history (9):
  • 2018/04 - 現在 RIKEN Laboratory for Intestinal Ecosystem, Center for Integrative Medical Sciences Team Leader
  • 2002/02 - 2013/03 RIKEN Research Center for Allergy and Immunology Team Leader
  • 1999/04 - 2004/03 金沢大学がん研究所教授
  • 1997/05 - 1999/03 Chiba University School of Medicine
  • 1991/04 - 1997/04 Chiba University School of Medicine Assistant Professor
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Awards (5):
  • 2021/11 - 持田記念医学薬学振興財団 持田記念学術賞 健康と病態に関わる宿主-腸内細菌相互作用の包括的理解
  • 2018 - 野口英世記念会 第61回野口英世記念医学賞 宿主-腸内細菌相互作用の総合的理解に関する研究
  • 2018 - 文部科学省 文部科学大臣表彰 科学技術賞(研究部門) 腸内環境の統合的研究
  • 2016 - ベーリンガーインゲルハイム 第53回ベルツ賞(2等賞) 宿主-腸内細菌叢相互作用
  • 2015 - 安藤スポーツ・食文化振興財団 第20回安藤百福賞大賞 腸内細菌が食物成分を分解して産生する代謝産物による 腸管免疫系制御の分子メカニズムの解明
Association Membership(s) (7):
日本癌学会 ,  日本生化学会 ,  日本分子生物学会 ,  日本細胞生物学会 ,  日本免疫学会 ,  日本消化器免疫学会 ,  腸内細菌学会
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