Rchr
J-GLOBAL ID:200901038919043070
Update date: Nov. 11, 2024
Funahashi Makoto
フナハシ マコト | Funahashi Makoto
Affiliation and department:
Job title:
Professor
Other affiliations (1):
Homepage URL (1):
http://www.den.hokudai.ac.jp/
Research field (1):
Oral medicine
Research keywords (6):
feeding behavior
, area postrema
, nausea, emesis
, limbic system
, 機能系基礎歯科学
, Oral physiology
Research theme for competitive and other funds (24):
- 2022 - 2025 Neurophysiological study for the elucidation of the difference of the central mechanism of nausea and vomiting and the development of the nausea suppression therapy.
- 2022 - 2025 Study of the mechanism of action of lipid rafts on general anesthetics by bioimaging and electrophysiological techniques.
- 2019 - 2022 Neurophysiological study of central mechanisms for nausea and vomiting to create a new antiemetic therapy.
- 2016 - 2019 Study of neuronal activity, a molecular basis and a behavioral change related to chemoreceptor-mediated nausea and emesis.
- 2016 - 2019 Analysis of hunger and satiety signalling pathway from peripheral to central nervous system using visualizing technology of a marker of neuronal activation
- 2015 - 2018 嘔吐誘発と摂食調節に関わる延髄最後野ニューロンの機能分化とその分子基盤の解明
- 2010 - 2012 Identification of emesis-inducing medullary neurons and anslysis of their functions.
- 2009 - 2012 Mechanisms of salivary gland atrophy induced by soft food
- 2009 - 2011 The effect of intraoperative hypotension on postoperative nausea and vomiting
- 2005 - 2006 Analysis of the functional and biological roles of the hyperpolarization-activated cation current in the central nervous system,
- 2005 - 2006 Electrophysiological study on development of inhibitory synaptic transmission in central neurons involved in oral function.
- 2003 - 2004 Analysis of the functional role of the hyperpolarization-activated cation cunert within the centaral nervous system.
- 2002 - 2004 静脈内鎮静法が嚥下に関連する中枢神経活動に及ぼす影響-機能的磁気共鳴画像(機能的MRI)による分析
- 2002 - 2003 Electrophysiological analysis of impulse formation in the salivary secretory neurons
- 1999 - 2000 扁桃体単一ニューロンの膜特性および海馬体との神経回路網に関する電気生理学的研究
- 1999 - 2000 Electrophysiological analysis of brainstem neurons subserving autonomic and motor oral functions
- 1997 - 1998 扁桃体の単一ニューロン特性及び海馬体との神経連絡に関する電気生理学的研究
- 1997 - 1998 Electrophysiological analysis of the lateral reticular formation controlling orofacial autonomic and motor functions
- 1994 - 1994 ラット最後野のグルコース応答性ニューロンに関する電気生理学的研究
- 1993 - 1994 Electrophysiological and microdialytic analysis on responses of dopaminergic and noradrenergic neurons in the medulla ablongata (A2aea)
- 1990 - 1990 ラット最後野中の内受容性ニューロンの受容機構に関する研究
- 1990 - 1990 摂食と延髄最後野の機能
- 1988 - 摂食・飲水行動調節の中枢神経機構
- 1988 - 1) Neurophysiology of the control of food intake and drinking.
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Papers (101):
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Tomohiko Yoshizawa, Makoto Funahashi. Dopamine release in striatal striosome compartments in response to rewards and aversive outcomes during classical conditioning in mice. Neuroscience Research. 2024
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Shaoyi Su, Zimo Wei, Helai Huang, Tomohiko Yoshizawa, Tadashi Inui, Makoto Funahashi. Conditioned nausea induced by cisplatin and emetine identified by a taste reactivity test in rats. Physiology & Behavior. 2023. 114278-114278
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Tomohiko Yoshizawa, Yuuto Miyamura, Yuta Ochi, Riichiro Hira, Makoto Funahashi, Yutaka Sakai, Yilong Cui, Yoshikazu Isomura. Working memory-based and -free reward prediction in a dual dopamine system in the basal ganglia. bioRxiv (preprint). 2023
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Emi Kikuchi, Tadashi Inui, Shaoyi Su, Yoshiaki Sato, Makoto Funahashi. Chemogenetic inhibition of the bed nucleus of the stria terminalis suppresses the intake of a preferable and learned aversive sweet taste solution in male mice. Behavioural brain research. 2023. 439. 114253-114253
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Shaoyi Su, Mayu Fujita, Zimo Wei, Helai Huang, Tomohiko Yoshizawa, Tadashi Inui, Makoto Funahashi. Effects of area postrema lesions and bilateral subdiaphragmatic afferent vagotomy on emetine-induced conditioned taste avoidance in rats. Physiology & Behavior. 2021. 241. 113565-113565
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MISC (28):
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舩橋誠, 平井喜幸, 藤田麻由, 久留和成, 前澤仁志. エメチン誘発の悪心に対する迷走神経切除と最後野損傷の影響. Journal of Oral Biosciences Supplement (Web). 2018. 2018
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前澤 仁志, 小金丸 聡子, 松橋 眞生, 舩橋 誠, 美馬 達哉. トレッドミル歩行時の歩行リズムに対する咀嚼リズムの引き込み現象. 臨床神経生理学. 2017. 45. 5. 434-434
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前澤 仁志, 美馬 達哉, 矢澤 省吾, 松橋 眞生, 白石 秀明, 舩橋 誠. ヒトの舌突出時の舌に関する舌筋電図コヒーレンスの対側優位性 MEG study(Contralateral dominance of corticomuscular coherence for the tongue during human tongue protrusion: An MEG study). 臨床神経生理学. 2014. 42. 5. 298-298
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奥舎有加, 奥舎有加, 平井喜幸, 前澤仁志, 山崎裕, 舩橋誠. L-ヒスチジン誘発の摂食抑制及び悪心誘発に対するノルアドレナリン作動性神経の関与. Journal of Oral Biosciences Supplement (Web). 2014. 2014
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平井喜幸, 前澤仁志, 舩橋誠. 最後野および孤束核のノルアドレナリン作動性ニューロンの悪心・嘔吐誘発への関与. Journal of Oral Biosciences Supplement (Web). 2014. 2014
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Books (7):
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歯科生理学実習
医歯薬出版 2022 ISBN:9784263458693
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基礎歯科生理学第7版
医歯薬出版 2020 ISBN:9784263458464
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基礎歯科生理学第7版
医歯薬出版 2020 ISBN:9784263458464
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歯・口腔の構造と機能 口腔解剖学・口腔組織発生学,口腔生理学
医歯薬出版 2011
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人体の構造と機能
医歯薬出版 2010
more...
Education (2):
- 1989 - 1989 Okayama University
- 1983 - 1989 Okayama University Dental School School of Dentistry
Professional career (1):
Work history (7):
- 2017/04 - 現在 北海道大学大学院歯学研究院 口腔医学部門 口腔機能学分野 口腔生理学教室 教授
- 2012/04 - 現在 Hokkaido University Research and Education Center for Brain Science
- 2008/02 - 2017/03 Department of Oral Physiology Graduate School of Dental Medicine Hokkaido University Professor
- 2005/04 - 2008/02 Department of Oral Physiology Graduate School of Dental Medicine Hokkaido University Associate Professor
- 2001/04 - 2005/03 Okayama University Dental School Research Associate
- 1989/10 - 2001/03 Okayama University Dental School,Department of Oral Physiology Research Associate
- 1995/06 - 1997/07 State Univ. of New York at Brooklyn, Downstate Medical Center, Department of Physiology, Postdoctral fellow
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Committee career (7):
Awards (1):
- 2001/09 - Japanese Association for Oral Biology Award from Japanese Association for Oral Biology Propagation of synchronous burst discharges from entorhinal cortex to morphologically and electrophysiologically identified neurons of rat lateral amygdala
Association Membership(s) (6):
日本生理学会北海道地方会
, HOKKAIDO ASSOCIATION FOR DENTAL SCIENCE
, PHYSIOLOGICAL SOCIETY OF JAPAN
, 歯科基礎医学会
, 日本神経科学学会
, 北米神経科学学会
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