Rchr
J-GLOBAL ID：200901039072412151   Update date: Jan. 30, 2024

Oshima Yoshiteru

オオシマ ヨシテル | Oshima Yoshiteru
Affiliation and department：
Tohoku University Head office for open innovation srategy

About Tohoku University Head office for open innovation srategy


Job title： Professor
Homepage URL  (2)： http://db.tohoku.ac.jp/whois/detail/d73126639060d210e039251c316c0e55.html ,  http://db.tohoku.ac.jp/whois/e_detail/d73126639060d210e039251c316c0e55.html
Research field  (3)： Pharmaceuticals - chemistry and drug development ,  Pharmaceuticals - chemistry and drug development ,  Molecular biochemistry
Research keywords  (1)： Biologically Active Natural Products
Research theme for competitive and other funds  (33)：
  • 2006 - 現在 Search for Anti-viral Compounds from South-african Medicinal Plants
  • 2016 - 2019 Novel screenings for unmet medical needs with innovative new natural product derived compounds
  • 2016 - 2019 多様性拡大抽出物を活用した薬理活性志向型天然化合物類縁体ライブラリーの構築
  • 2015 - 2019 Research on pharmacologically active molecule DIF found in the cellular slime mold Dictyostelium discoieum
  • 2015 - 2017 Use of Fungal Strains Resistant to Ribosome Targeting-Antibiotics for Discovery of Cryptic Secondary Metabolites
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Papers (219)：
  • Hirotaka Kanoh, Shinzo Iwashita, Takayuki Kuraishi, Akira Goto, Naoyuki Fuse, Haruna Ueno, Mariko Nimura, Tomohito Oyama, Chang Tang, Ryo Watanabe, et al. cGMP signaling pathway that modulates NF-κB activation in innate immune responses. iScience. 2021. 24. 12. 103473-103473
  • Yoshihide Suzuki, Keisuke Ichinohe, Akihiro Sugawara, Shinya Kida, Shinya Murase, Jing Zhang, Osamu Yamada, Toshio Hattori, Yoshiteru Oshima, Haruhisa Kikuchi. Development of Indole Alkaloid-Type Dual Immune Checkpoint Inhibitors Against CTLA-4 and PD-L1 Based on Diversity-Enhanced Extracts. Frontiers in Chemistry. 2021. 9
  • Toshihiro Mita, Makoto Hirai, Yoshiko Maki, Saifun Nahar, Naoko Yoshida, Yoshiteru Oshima, Haruhisa Kikuchi, Yuzuru Kubohara. Derivatives of Dictyostelium differentiation-inducing factors suppress the growth of Plasmodium parasites in vitro and in vivo. Biochemical Pharmacology. 2021. 114834-114834
  • Yuzuru Kubohara, Yoshimi Homma, Hiroshi Shibata, Yoshiteru Oshima, Haruhisa Kikuchi. Dictyostelium Differentiation-Inducing Factor-1 Promotes Glucose Uptake, at Least in Part, via an AMPK-Dependent Pathway in Mouse 3T3-L1 Cells. International Journal of Molecular Sciences. 2021. 22. 5. 2293-2293
  • Hitomi Sasaki, Yuzuru Kubohara, Hirotaka Ishigaki, Katsunori Takahashi, Hiromi Eguchi, Akihiro Sugawara, Yoshiteru Oshima, Haruhisa Kikuchi. Two New Terpenes Isolated from Dictyostelium Cellular Slime Molds. Molecules. 2020. 25. 12. 2895-2895
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MISC (31)：
  • Takehiro Nishimura, Junya Kawai, Yoshiteru Oshima, Haruhisa Kikuchi. Removal of the E-Olefin Barrier of Humulene Leading to Unnatural Terpenoid-like Skeletons (vol 20, pg 7313, 2018). ORGANIC LETTERS. 2019. 21. 4. 1241-1241
  • KUBOHARA Yuzuru, KIKUCHI Haruhisa, OSHIMA Yoshiteru. Derivatives of Dictyostelium differentiation-inducing factors inhibit serum-dependent cell migration of murine osteosarcoma LM8 cells. Juntendo Medical Journal. 2018
  • Teigo Asai, Yoshiteru Oshima. [The application of epigenetic regulation for natural products discovery]. Seikagaku. The Journal of Japanese Biochemical Society. 2016. 88. 5. 643-8
  • 浅井 禎吾, 大島 吉輝. 微生物の可能性を開拓する : 多様な新規化合物合成のための新しいアプローチ. 現代化学 = Chemistry today. 2016. 546. 21-26
  • 青木 淳賢, 可野 邦行, 濱 直人, 辻田 忠志, 土井 隆行, 菅原 明, 清水 律子, 大島 吉輝, 山本 雅之. 動き出した創薬オープンイノベーションネットワーク アカデミック創薬 東北からの発信. 日本薬学会年会要旨集. 2015. 135年会. 1. 155-155
ｍore...
Books (2)：
  • Pharmacognosy and Natural Product Chemistry
    Kagakudojin 2008
  • 薬学からみた細胞性粘菌
    アイピーシー 2000
Education (2)：
  • - 1977 Tohoku University Graduate School, Division of Pharmaceutical Sciences 製薬化学
  • - 1975 Tohoku University Faculty of Pharmaceutical Science 薬学
Professional career (2)：
  • 薬学博士 (Tohoku University)
  • 薬学修士 (Tohoku University)
Work history (4)：
  • 1992/04 - 1996/03 Faculty of Engineering, Aomori University Associate Professor
  • 1977/04 - 1992/03 Pharmaceutical Institute, Tohoku University Instructor
  • 1992/03 - Institute of Pharmaceutical Sciences 講師
  • 1982/12 - 1984/11 School of Pharmacy, University of Illinois at Chaicago Research Associate
Committee career (6)：
  • 2007/04 - 2010/03 日本薬学会 創薬セミナーアドバイザー
  • 2007/04 - 2010/03 日本薬学会 創薬セミナーアドバイザー
  • 2007/03 - 日本薬学会 医薬化学部会国際担当幹事
  • 2007/03 - 日本薬学会 医薬化学部会国際担当幹事
  • 2000/04 - 2002/03 日本生薬学会 評議員
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Association Membership(s) (2)：
日本生薬学会 ,  日本薬学会
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