Rchr

J-GLOBAL ID：200901039417477650 Update date: Oct. 11, 2024

Yoshinari Nobuo

ヨシナリノブオ | Yoshinari Nobuo

Affiliation and department：

Research field (1)： Conservative dentistry and endodontics

Research keywords (1)： Periodontal Medicine

Research theme for competitive and other funds (54)：

2024 - 2028 食塩過剰摂取が認知症型口腔内細菌叢および歯周病治療予後に与える影響
2024 - 2027 Development of a new comprehensive treatment for periodontal disease, diabetes and atherosclerosis with senescent cell therapeutics.
2022 - 2025 画像指標と臨床所見を統合した脆弱性骨折リスク患者スクリーニングシステムの開発
2022 - 2025 歯周病ー老化ー糖尿病の相互関連性の解明と新たな治療戦略の確立
2021 - 2024 自立度別100歳代と80歳代の口腔及び腸内細菌叢の比較と寿命に影響する因子の解明

2021 - 2024 慢性炎症が基盤病態の歯周病,糖尿病,動脈硬化症に対する抗老化細胞療法の創出

2020 - 2023 老化因子除去による新規の歯周病治療法の確立

2019 - 2022 Development of a potential new marker of periodontal disease status based on serum IL-1 receptor accessory protein .

2018 - 2021 ロイコトキシン-受容体相互作用に関する分子基盤の解明と新規歯周炎ワクチンの開発

2018 - 2021 Development of the new periodontal treatments based on the regulation of sclerostin secretion

2018 - 2021 Elucidation of molecular basis for the relationship between periodontal disease and atherosclerosis by controlling aging

2018 - 2021 Development of screening system for identifying individuals with lifestyle-related fragility fractures by oral and maxillofacial image indices

2017 - 2020 Analysis and clinical application of new function of osteoprotegerin as anti-aging factor

2017 - 2020 Association subtype of age-relrated macular degeneration and periodontal disease

2015 - 2019 Effects of carotid artery stiffness related with periodontitis on central arterial pressure and baroreflex sensitivity

2015 - 2018 Bacteriological and immunological analysis for the regulatory factors of aggressive periodontitis in Morocco

2015 - 2018 Construction of the new osteoporosis screening system which unified indices detected on oral and maxillofacial image

2015 - 2018 Clofibrate produce IL-1Ra and inhibit the experimental periodontitis

2014 - 2017 Effects of periodontal disease via serum amyloid A on aging on the mechanism of exacerbation of arteriosclerosis

2012 - 2015 Risk estimation of osteoporotic fracture and atherosclerosis by oral health indices on panoramic radiographs

2011 - 2013 The onset diagnosis of the arteriosclerosis by periodontitis through the serum amyloid A.

2009 - 2011 Development of oral health-related indices for identifying individuals with increased risk of ischemic cardiovascular diseases

2009 - 2011 The establishment of a guideline of antibiotics and Kampo medicine for periodontal disease therapy

2008 - 2010 Prediction study of atherosclerosis by periodontal disease through serum amyloid A.

2006 - 2007 Integrative Study for the Impacts of Periodontal Disease on Metabolic Syndrome

2004 - 2006 Effect of restraint stress on the gene expression in periodontal tissue of rat experimental periodontitis

2002 - 2006 歯周病と心臓血管疾患との関連

2004 - 2005 Development of the noble biomaterial for re-implantation to host consisiting of chondrocyte culture system and titanium system

2001 - 2003 The mRNA expression of neuropeptide-receptor on the cells around the alveolar bone tinder the stressful condition in rats.

1999 - 2001 Comprehensive Study for the Relationship between Stress, Periodontal Disease and Systemic Disease

1996 - 2000 GKラットにおけるカルシウム遊離能の研究

1996 - 2000 Study of Ca release in GK rat

1998 - 1999 The relationship between diabetes mellitus and experimental periodontitis in assaciation with neurogenic inflammation

1998 - 1998 ストレスと歯周病の関連性についての実験的研究

1996 - 1996 自然発症糖尿病ラットにおける実験的歯周炎の病理組織学的研究

1996 - ストレスと歯周病の関係

1996 - The relationship between stress and periodontal disease

1995 - 1995 自然発症糖尿病ラットにおける実験的歯周炎の病理組織学的研究

1994 - 1994 自然発症糖尿病ラットにおける実験的歯周炎の病理組織学的研究

1990 - 1994 自然発症糖尿病(GK:後藤-柿崎)ラットにおける実験的歯周炎-高ショ糖溶液の影響-

1990 - 1994 Experimental Periodontitis in Spontaneous Diabetic (GK : Goto-Kakizaki) Rats -Effect of High-sucrose solution-

1993 - 1993 自然発症糖尿病ラットにおける実験的歯周炎の病理組織学的研究

1992 - 1993 A study on the relationship between tooth to denture base discrepancy and periodontal disease.

1991 - 1993 The Effect of Chemotherapy on The Local Environment in The Pocket

1992 - 1992 自然発症糖尿病ラットにおける実験的歯周炎の病理組織学的研究

1991 - 1991 自然発症糖尿病ラットにおける実験的歯周炎の病理組織学的研究

1990 - 骨縁下欠損に対する非吸収性膜による組織再生誘導法の長期経過症例の臨床的検討

歯周病と急性期蛋白との関係

全身疾患と歯周病羅患に関する疫学調査

骨代謝における神経系ペプタイドの関与

The relationship between periodoutal disease and acute phase protein.

Epidemiologic Study of the Relationship Between Systemic Disease and the Prevalence of Periodontal Disease

Effect of Neuropeptide on Bone Metabolism

Long-term clinical evaluation of nonresorbable membranes in the treatment of intrabony detects following guided tissue regeneration

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Papers (143)：

Yuki Ohtani, Masato Yamaguchi, Shuichiro Yamashita, Kazuhiro Yamada, Yasuhiro Tai, Ryuichi Mizutani, Yuki Ozaki, Nanae Dewake, Keiichi Uchida, Nobuo Yoshinari. A case report of interdisciplinary treatment for broad type periodontitis patient. Journal of Interdisciplinary Clinical Dentistry. 2024. 5. 1. 1-14
Aya Miyashita-Kobayashi, Akiko Haruyama, Keigo Nakamura, Chia-Ying Wu, Akihiro Kuroiwa, Nobuo Yoshinari, Atsushi Kameyama. Changes in Gloss Alteration, Surface Roughness, and Color of Direct Dental Restorative Materials after Professional Dental Prophylaxis. Journal of Functional Biomaterials. 2023. 15. 1. 8-8
中村圭吾, 石原裕一, 亀山敦史, 吉成伸夫, 宇田川信之, 小出雅則. スクレロスチン欠損はBMP-2誘導性異所性骨の石灰化を促進させる. 特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集. 2023. 159回. 137-137
Nanae Dewake, Manabu Miki, Yasuaki Ishioka, Suguru Nakamura, Akira Taguchi, Nobuo Yoshinari. Association between clinical manifestations of occlusal trauma and magnetic resonance imaging findings of periodontal ligament space. Dentomaxillofacial Radiology. 2023
Keigo Nakamura, Masanori Koide, Yasuhiro Kobayashi, Teruhito Yamashita, Mai Matsushita, Hisataka Yasuda, Yuichi Ishihara, Nobuo Yoshinari, Nobuyuki Udagawa. Sclerostin deficiency effectively promotes bone morphogenetic protein-2-induced ectopic bone formation. Journal of Periodontal Research. 2023. 58. 4. 769-779

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MISC (162)：

Nobuyuki Udagawa, Masanori Koide, Midori Nakamura, Akira Taguchi, Nobuo Yoshinari. Crosstalk between periodontal disease and osteoporosis. 2024. 66. 1. 9-16
吉成伸夫. コラム歯科健診で糖尿病予防!?. OPJリエゾン. 2023. 26-26
吉成伸夫. [誌上シンポジウム]レーザー光が拓く歯科保存治療・シンポジウム概要. 日本歯科保存学雑誌. 2023. 66. 2. 94-94
吉成伸夫, 中村卓. 歯周病と誤嚥性肺炎. 健康と生活. 2023. 544. 6-7
出分菜々衣, 吉成伸夫. ミニレビュー歯周疾患検診の変遷と現状ならびに国民皆歯科健診の具体的検討. 日歯周誌. 2022. 64. 4. 1-20

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Books (50)：

特定非営利活動法人日本歯周病学会編歯周病患者における再生療法のガイドライン2023
2023
老年歯科医学用語辞典第3版
医歯薬出版株式会社(東京) 2023
特定非営利活動法人日本歯周病学会編歯周治療のガイドライン2022
医歯薬出版株式会社(東京) 2022
Printed Edition of the Special Issue Published in Journal of Clinical Medicine “Prevention and Treatment of Periodontitis”
Journal of Clinical Medicine 2021
JSP Guidelines for the Use of Antimicrobial Agents in Patients with Periodontal Disease 2020
2020

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Works (8)：

全身疾患と歯周病罹患に関する疫学調査
2001 - 2002
Epidemiological Study on the Relationship Between Systemic diseases and Perio douful Disease
2001 - 2001
ストレスと歯周疾患・全身疾患に関する総合的研究
1999 - 2001
Synthetic Study on the Relationship Stress and Periodontal Disease, Systemic Disease
1999 - 2001
エムドゲイン<sup>®</sup>に関する市販後調査
1999 - 2000

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Education (3)：

1986 - 1990 Aichi Gakuin University Graduate School of Dentistry
1980 - 1986 Aichi Gakuin University School of Dentistry Department of Dentistry
1977 - 1980 大阪府立高津高校

Professional career (1)：

Doctor of Dentistry (Aichi Gakuin University)

Work history (11)：

2021/04 - 現在昭和大学歯学部歯周病学講座(昭和大学歯科病院歯周病科) 客員教授
2014/04 - 現在 Matsumoto Dental University Department of Periodontology Professor
2000/10 - 現在 The Japanese Society of Periodontology
1992/11 - 現在 Japanese Society of Periodontology
2012/04 - 2015/03 松本歯科大学病院副病院長

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Committee career (15)：

2019/04 - 現在 Japanese Society of Periodontology Specialist Committee Chairman
2011/04 - 現在 Japanese Society of Laser Dentistry director
2011/04 - 現在 Japanese Society of Periodontology Standing director
2007/04 - 現在 Japanese Society of Conservative Dentistry director
2007/04 - 現在 Japanese Society of Periodontology director

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Awards (2)：

2017/05 - The Japanese Society of Periodontology AAP-JSP 2016 San Diego JSP poster award Analysis of the relationship between periodontal disease and diabetes mellitus.
2013/05 - The Japanese Society of Periodontology AAP-JSP 2012LA JSP poster award The effect of SAA on atherosclerosis in ApoE defficient mice.

Association Membership(s) (8)：

日本老年歯科医学会 , Japanese Society for Laser Dentistry , The American Academy of Periodontology , Japanese Association for Dental Research , International Association for Dental Research , Japanese Society of Conservative Dentistry , 愛知学院大学歯学会 , Japanese Society of Periodontology

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