Rchr
J-GLOBAL ID:200901039420217830   Update date: Feb. 25, 2024

Kaji Hirokazu

カジ ヒロカズ | Kaji Hirokazu
Affiliation and department:
Job title: Professor
Homepage URL  (1): https://www.tmd.ac.jp/bmc
Research field  (5): Nanobioscience ,  Nanomaterials ,  Biomaterials ,  Biomedical engineering ,  Nano/micro-systems
Research keywords  (6): Biointerface ,  Biomaterial ,  Biodevices ,  Cell and Tissue Engineering ,  Microfluidics ,  Drug delivery
Research theme for competitive and other funds  (20):
  • 2023 - 2026 Creation of in vitro evaluation systems for integrated understanding of oral dysbiosis and systemic diseases
  • 2022 - 2024 Preparation of organoids with human placental structure and construction of placental barrier ability evaluation system
  • 2021 - 2024 妊娠高血圧症候群の発症機序の解明に向けたヒト栄養膜細胞の血管浸潤モデルの開発
  • 2018 - 2020 Fabrication of donut-shaped drug release sheet that develops in the vitreous body
  • 2017 - 2020 Construction of an in vitro eye disease platform
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Papers (176):
  • Shun Shibata, Shun Endo, Luis A. E. Nagai, Eri H. Kobayashi, Akira Oike, Norio Kobayashi, Akane Kitamura, Takeshi Hori, Yuji Nashimoto, Ryuichiro Nakato, et al. Modeling embryo-endometrial interface recapitulating human embryo implantation. Science Advances. 2024. 10. 8
  • Takeshi Hori, Hiroaki Okae, Shun Shibata, Norio Kobayashi, Eri H Kobayashi, Akira Oike, Asato Sekiya, Takahiro Arima, Hirokazu Kaji. Trophoblast stem cell-based organoid models of the human placental barrier. Nature communications. 2024. 15. 1. 962-962
  • Yuji Nashimoto, An Konno, Takuto Imaizumi, Kaori Nishikawa, Kosuke Ino, Takeshi Hori, Hirokazu Kaji, Hirofumi Shintaku, Masafumi Goto, Hitoshi Shiku. Microfluidic vascular formation model for assessing angiogenic capacities of single islets. Biotechnology and bioengineering. 2023
  • Serge Ostrovidov, Murugan Ramalingam, Hojae Bae, Gorka Orive, Toshinori Fujie, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji. Molecularly Imprinted Polymer-Based Sensors for the Detection of Skeletal- and Cardiac-Muscle-Related Analytes. Sensors. 2023. 23. 12. 5625-5625
  • Hiroya Abe, Tomoya Ina, Hirokazu Kaji, Matsuhiko Nishizawa. Mussel-inspired interfacial ultrathin films for cellular adhesion on the wrinkled surfaces of hydrophobic fluids. Polymer Journal. 2023
more...
MISC (144):
  • 水田太郎, 石原甲平, 梶弘和, 堀武志. Development of artificial human tissues using micromesh sheets. 生体医歯工学共同研究拠点成果報告会. 2022. 2021 (CD-ROM)
  • 水田太郎, 石原甲平, 梶弘和, 堀武志. Development of artificial human tissues using micromesh sheets. 生体医歯工学共同研究拠点成果報告書. 2022. 2021
  • 天野倉大成, 堀武志, 小林記緒, 岡江寛明, 有馬隆博, 梶弘和. Development of the human placental model using microfluidics device. 日本バイオマテリアル学会大会予稿集(Web). 2021. 43rd
  • 天野倉大成, 堀武志, 小林記緒, 岡江寛明, 有馬隆博, 梶弘和. Development of a microfluidic device for functional evaluation of the human placenta. 応用物理学会秋季学術講演会講演予稿集(CD-ROM). 2021. 82nd
  • 山田輝拓, 堀武志, 永井展裕, 阿部俊明, 梶弘和. 細胞培養カプセルを用いたサイトカインデリバリーシステムの開発. 化学とマイクロ・ナノシステム学会研究会講演要旨集. 2021. 43rd (CD-ROM)
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Patents (6):
  • 細胞担持パターン化ナノ薄膜
  • タンパク質および細胞が内壁に固定された中空構造体
  • 持続性ドラッグデリバリーシステム
  • 角膜経上皮電気抵抗値の測定方法
  • 細胞または組織の培養制御装置とその方法
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Books (14):
  • Microfluidic Cell Culture Systems, 2nd Edition
    Elsevier Publishing 2019
  • 臓器チップの技術と開発動向
    シーエムシー出版 2018
  • Retinal Degenerative Diseases, Advances in Experimental Medicine and Biology, vol 854.
    Springer 2016
  • Stem Cell Biology and Tissue Engineering in Dental Sciences
    Elsevier Publishing 2015
  • Retinal Degenerative Diseases, Advances in Experimental Medicine and Biology, vol 801.
    Springer 2014
more...
Lectures and oral presentations  (87):
  • Development of a multilayered drug-delivery sheet that allows minimally invasive delivery to the eye
    (EMBS Micro and Nanotechnology in Medicine Conference 2018)
  • Microfluidic cell culture model of the outer-blood-retina-barrier
    (EMBS Micro and Nanotechnology in Medicine Conference 2018)
  • Development of an implantable cell culture device for retinal diseases
    (EMBS Micro and Nanotechnology in Medicine Conference 2018)
  • Development of a human corneal model using a blinking eyelid device
    (EMBS Micro and Nanotechnology in Medicine Conference 2018)
  • Microfluidic model of the outer blood-retina-barrier
    (MicroTAS 2018 2018)
more...
Education (3):
  • 2003 - 2005 Tohoku University Graduate School of Engineering Department of Bioengineering and Robotics
  • 2001 - 2003 Tohoku University Graduate School of Engineering Department of Biomolecular Engineering
  • 1997 - 2001 Tohoku University School of Engineering Department of Molecular Chemistry and Engineering
Professional career (1):
  • Ph.D. (Tohoku University)
Work history (8):
  • 2023/04 - 現在 Keio University Faculty of Pharmacy, Graduate School of Pharmaceutical Sciences Visiting Professor
  • 2021/10 - 現在 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering Professor
  • 2017/10 - 2021/09 Tohoku University Graduate School of Biomedical Engineering Associate Professor
  • 2011/01 - 2021/09 Tohoku University Graduate School of Engineering Associate Professor
  • 2009/09 - 2011/08 Harvard-MIT Division of Health Sciences and Technology JSPS Fellow for Research Abroad
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Committee career (38):
  • 2022/05 - 現在 Society for Chemistry and Micro-Nano Systems Director
  • 2018/04 - 現在 The Japanese Society for Biomaterials Councillor
  • 2011/01 - 現在 Journal of Biomaterials and Tissue Engineering Associate Editor
  • 2022 - 2024 PRiME2024 PRiME2024実行委員会幹事委員
  • 2023/07 - IEEE EMBC’23 Conference Editorial Board Reviewer
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Awards (16):
  • 2022/12 - 公益財団法人カシオ科学振興財団 研究助成(特別テーマ)
  • 2019/12 - 一般財団法人青葉工学振興会 青葉工学振興会賞
  • 2018/05 - 公益財団法人インテリジェント・コスモス学術振興財団 インテリジェント・コスモス奨励賞
  • 2018/03 - 公益財団法人テルモ生命科学芸術財団 テルモ生命科学芸術財団研究開発助成
  • 2016/04 - 化学とマイクロ・ナノシステム学会 化学とマイクロ・ナノシステム学会奨励賞
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Association Membership(s) (11):
The Association for Research in Vision and Ophthalmology ,  Japanese Society of Biorheology ,  The Japan Society of Mechanical Engieers ,  The Electrochemical Society of Japan ,  日本動物実験代替法学会 ,  Japanese Society for Medical and Biological Engineering ,  Society For Biomaterials ,  Biomedical Engineering Society ,  Society for Chemistry and Micro-Nano Systems ,  The Japan Society of Drug Delivery System ,  Japanese Society for Biomaterials
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