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J-GLOBAL ID：200901039559034160 Update date: May. 06, 2025

Ohta Makoto

オオタマコト | Ohta Makoto

Affiliation and department：
Job title： Professor
Other affiliations (2)：

Tohoku University Graduate School of Engineering Professor
Tohoku University Graduate School of Biomedical Engineering Professor

Homepage URL (2)： http://www.ifs.tohoku.ac.jp/jpn/crfrd_bfdl.html , https://www.ifs.tohoku.ac.jp/eng/research/dv_crfrd/bfdl

Research field (4)： Neurosurgery , Fluid engineering , Biomaterials , Biomedical engineering

Research keywords (7)： oral , wear , interventional radiology , aneurysm , blood flow , 3D reconstruction , biomodelling

Research theme for competitive and other funds (26)：

2022 - 2025 合併症を再現できる内視鏡手技シミュレータを展開し、有効な学習プログラムを構築する
2022 - 2025 Effect of wall elasticity on hemodynamics inside patient-specific cerebral aneurysm
2022 - 2025 慢性関節炎の微小血管塞栓術に関する基礎実験
2022 - 2025 Establishment of a prediction model for aneurysm development by mathematical vascular branching pattern classification and vascular travel standardisation.
2021 - 2024 TiO2 layer formation on super elastic NiTi alloy via anodization

2021 - 2024 Visualization of stroke risk using standard model of MRA vascular course and wall stress

2021 - 2024 アイトラッキングによるカテーテル術者の目線解析と訓練に役立つ目線パターンの解明

2021 - 2024 Development of the implant for the reduction of vascular stenosis of AV fistula of hemodialysis patients

2020 - 2023 Study of Structural and Thermal Properties of PVA as 3D Printing Material for Body Parts Modeling

2019 - 2022 Characteristics of elasticity on suppression for progress and rupture in cerebral aneurysm

2017 - 2022 Development of efficient nonclinical evaluation system for innovative medical equipment flow diverte

2021 - 2022 Development of a novel arterial lesion vessel model for pulsatile cerebrovascular circulatory simulation

2018 - 2021 Fluid mechanical basic research for the treatment of dissecting aortic aneurysms with multi-layered blood flow control stents

2016 - 2021 Wearable Vital Sign System for Health Care Clothing based on FBG sensor

2017 - 2020 Development of new stent for the treatment of intracranial fusiform aneurysms to cure the aneurysmal wall and preserve perforators

2016 - 2019 Pulmonary blood flow analysis based on morphological and functional images in chronic thromboembolic pulmonary hypertension

2016 - 2019 Analysis of the mechanism of aortic diameter enlargement of Stanford type B dissection and development of prediction method

2016 - 2018 Research on endotheliaisation of optimal stent struts under blood flow(Fostering Joint International Research)

2013 - 2016 stent optimization for endothelialization with flow condition

2013 - 2016 Prediction of the wall property and rupture risk of cerebral aneurysms based on the computational fluid dynamics

2012 - 2016 Development of a new catheter for segmental adrenal venous sampling

2012 - 2015 Study on the next generation stent construction for cerebral aneurysm

2011 - 2014 Development of minimally-invasive interventional radiological therapy of primary aldosteronism based on adrenal venous sampling.

2007 - 2009 Time-dependent blood flow analysis with measurement coupled simulation

2006 - 2007 シネマティックアンギオを用いた脳動脈瘤内の血流フローダイナミクス計測法の開発

2001 - Biomedical Engineering

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Papers (369)：

Ryo Shimodoumae, Gaku Tanaka, Ryuhei Yamaguchi, Makoto Ohta. Numerical simulation of flow behavior in basilar bifurcation computed tomography angiography. International Journal for Numerical Methods in Biomedical Engineering. 2024. 40. 4
Fangjia Pan, Philippe Bijlenga, Naoko Mori, Shunji Mugikura, Makoto Ohta, Hitomi Anzai. Exploring the Variations in Angles Around Basilar Bifurcation Categorized by Aneurysm Locations. 2023 15th Biomedical Engineering International Conference (BMEiCON). 2023
Xuelan Zhang, Baoyan Mao, Yue Che, Jiaheng Kang, Mingyao Luo, Aike Qiao, Youjun Liu, Hitomi Anzai, Makoto Ohta, Yuting Guo, et al. Physics-informed neural networks (PINNs) for 4D hemodynamics prediction: An investigation of optimal framework based on vascular morphology. Computers in Biology and Medicine. 2023
Fangjia Pan, Naoko Mori, Shunji Mugikura, Philippe Bijlenga, Makoto Ohta, Hitomi Anzai. Generalized versus Specific Boundary Conditions for CFD in vertebral-basilar artery. 2023 8th International Conference on Instrumentation, Control, and Automation (ICA). 2023
Xuelan Zhang, Yuan Peng, Gaoyang Li, Jiehua Li, Mingyao Luo, Yue Che, Liancun Zheng, Hitomi Anzai, Makoto Ohta, Chang Shu. Elongation of the proximal descending thoracic aorta and associated hemodynamics increase the risk of acute type B aortic dissection. Technology and health care : official journal of the European Society for Engineering and Medicine. 2023

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MISC (198)：

Makoto Ohta, Naoya Sakamoto, Kenichi Funamoto, Zi Wang, Yukiko Kojima, Hitomi Anzai. A Review of Functional Analysis of Endothelial Cells in Flow Chambers. JOURNAL OF FUNCTIONAL BIOMATERIALS. 2022. 13. 3
坪子侑佑, 岡本吉弘, 太田信. Development of a novel arterial lesion vessel model for pulsatile cerebrovascular circulatory simulation. 東北大学流体科学研究所共同利用・共同研究拠点流体科学国際研究教育拠点活動報告書(CD-ROM). 2021. 2021
岡本吉弘, 庄島正明, 新妻邦泰, 太田信, 植松美幸, 迫田秀行, 配島由二. コイル塞栓術における脳血管内治療医の注視点の特徴と経験症例数との関係. 人工臓器(日本人工臓器学会). 2020. 49. 2
芳賀洋一, 芳賀洋一, 吉田洋, 松永忠雄, 清水康智, 太田信, 太田信, 庄島正明, 益田泰輔, Yu Kaihong, et al. Cerebrovascular Model Equipped with Microsensors. 電気学会論文誌 E. 2020. 140. 12
大石卓弥, 高嶋一登, 葭中潔, YU Kaihong, 太田信, 森浩二, 当麻直樹. Development of Device Placement Simulator for Endovascular Treatment (Evaluation of Coil Contact Force and Catheter Motion). 日本機械学会バイオフロンティア講演会講演論文集(CD-ROM). 2020. 31st

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Patents (6)：

PCT出願標準血管生成装置、血管評価装置、標準血管生成プログラム、血管評価プログラム、標準血管生成方法及び血管評価方法
多機能体内留置ステント
骨模型
生体模型のための粘膜材
マウスガード及びマウスガード用乾燥ゲルの製造方法

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Books (5)：

New trend of Intervention
Institute of advanced treatment and technology 2004
Safety and Bio compatibility of Bio materials and Medical devices
CMC publisher 2003
Computational Science-ICCS
P.M.A 2003
Joint Arthroplasty
Springer-Verlag Tokyo 1999
Adv. in Polym. Biomate. Sci
1997

Lectures and oral presentations (381)：

超音波検査用バイオモデル材料のPVA-H 3Dプリンタへの応用
(日本機械学会東北支部第56期総会・講演会 2021)
脳血管確率アトラスに基づく脳血管自動ラベル付けプログラムの開発(第1報、中心線に基づく確率アトラスのラベル付け精度の評価)
(第54回日本生体医工学会東北支部大会, 2021)
Optimization of stent structure based on blood flow simulation
(2ND INTERNATIONAL SYMPOSIUM ON COMPUTATIONAL BIOFLUID 2020 2020)
CFD analysis of AVF for hemodialysis
(2ND INTERNATIONAL SYMPOSIUM ON COMPUTATIONAL BIOFLUID 2020 2020)
The influence brought by specific boundary conditions on vascular simulations
(2ND INTERNATIONAL SYMPOSIUM ON COMPUTATIONAL BIOFLUID 2020 2020)

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Education (2)：

- 2001 Kyoto University Graduate School, Division of Engineering Department of Polymer Chemistry
- 1995 Tokyo University of Agriculture and Technology Faculty of Engineering Department of Materials and Bioengineering

Professional career (1)：

Dr. of Engineering (Kyoto University)

Work history (4)：

2022/03 - 現在 Tohoku University Graduate School of Biomedical Engineering Professor
2022/03 - 現在 Tohoku University Graduate School of Engineering Professor
2001/09 - 2004/12 University of Geneva post-doctoral
2001/04 - 2001/09 Institute of Frontier Medical Sciences, Kyoto University Lecturer (research worker of organization)

Committee career (25)：

2019/08 - 現在医療用立体モデルコンソーシアム幹事
2019/04 - 現在 Head
2019/04 - 現在戦略的国際標準化加速事業・政府戦略分野に係わる国際標準開発活動「バイオセラミックスの生物学的多能性評価に関する国際標準化」委員
2018/10 - 現在 ISO/TC150/WG14 議長
2018/04 - 現在日本生体医工学会東北支部役員

2016/04 - 現在 ISO/TC150 国内委員会委員

2016/02 - 現在機械学会バイオエンジニアリング部門 A-TS02-16 脳神経血管内治療に関する医工学連携研究会 Head

2013/01 - 現在日本機械学会編集委員

2020/04 - 2023/03 経済産業省事業「AMによる患者適合型支援システム造形に関する国際標準」委員

2019/04 - 2021/03 日本機械学会東北支部 55期商議委員会計幹事

2019/04 - 2021/03 PMDA第4期科学委員会「コンピューターシミュレーションを活用した医療機器ソフトウエアの審査の考え方」専門部会委員

2019/04 - 2020/03 Associate Editor

2017/04 - 2019/03 海綿骨モデルを含脊椎骨周辺のモデルの力学的測定方法に関する国際標準化委員会 PI

2009/09 - 2018/03 Intracranial Stent Meeting HP管理

2016/04 - 2018 次世代医療機器・再生医療等製品評価指標作成事業血流解析シミュレーションソフトウェア分野審査ワーキンググループ委員

2014/04 - 2016/03 模擬骨の3次元構造体に要求される特性に関する国際標準化委員会 PI

2014/04 - 2016 PMDA(独立行政法人医薬品医療機器総合機構)科学委員会委員委員

2011/04 - 2014/03 PI

2010/04 - 2012/03 日本機械学会バイオエンジニアリング部門運営委員会

2009/09 - Intracranial Stent Meeting admin of Web site

2005/03 - 2006/09 Intra cranial stent meeting 2006 (ICS06) Program organizer of Intra cranial stent meeting 2006 (ICS06)

2005/03 - 2006/09 Intra cranial stent meeting 2006 (ICS06) Intra cranial stent meeting 2006 (ICS06)のプログラム委員

2004/10 - 2005/01 Intra cranial stent meeting 2004 (ICS04) oranizer of Intra cranial stent meeting 2004

2004/10 - 2005/01 Intra cranial stent meeting 2004(ICS04) Intra cranial stent meeting 2004の実行委員

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Awards (20)：

2021/02 - 日本機械学会日本機械学会フェロー
2016/11/27 - 13th International IntraCranial Stent Meeting Poster Award(13th International IntraCranial Stent Meeting Correlating MR Wall Enhancement and Wall Shear Stress: Does CFD work to predict aneurysm instability?
2016/11/27 - 13th International IntraCranial Stent Meeting Poster Award(13th International IntraCranial Stent Meeting Exploring the relationship between the inflow zone and strut positions within the aneurysm orifice: a hemodynamic simulation study
2016/11/27 - 13th International IntraCranial Stent Meeting Poster Award(13th International IntraCranial Stent Meeting Blood Flow Into Basilar Tip Aneurysms A Predictor for Recanalization After Coil Embolization
2016/09/27 - 東北大学東北大学藤野先生記念奨励賞

2016/09/18 - 生体医工学シンポジウムポスターアワード(生体医工学シンポジウム2016 Introduction of Evaluation of Endoleak in Ink Flow Study

2015/11/14 - ICS2015 Best Student Presentation Award Student Presentation Award

2015/11/14 - ICS2015 Student Presentation Award

2015/02/20 - ElyT ElyT Workshop 2014 best poster award best poster award

2012/11/20 - ICS2012 Intracranial Stent Meeting 2012(ICS 2012) Best Abstract Presentation

2012/11/04 - エドモンド・オプティクス・ジャパン株式会社教育助成金プログラム 2011年度アジア部門1位 PVAを用いた脳動脈瘤モデルにおける壁挙動とPIV計測

2007/11 - 第23回日本脳神経血管内治療学会第23回日本脳神経血管内治療学会ポスター銀賞

2007/11 - 第23回日本脳神経血管内治療学会第23回日本脳神経血管内治療学会優秀演題

2005/11/21 - The 6th International Symposium on Future Medical Engineering based on Bio-nanotechnology (21st Century COE Program) Young Investigator Award Development of a Functional Vessel Biomodelling with Poly (vinyl alcohol) Hydrogel for In-vitro Simulation

2004/11 - 第20回日本脳血管内治療年学会 The 20th annual meeting of The Japanese Society for Endovascular Treatment bronze prize Measurement of intra-aneurysmal flow dynamics at stent implant

2004/11 - 第20回日本脳血管内治療年学会 Bronze Prizes The 20th annual meeting of The Japanese Society for Endovascular Treatment シネマティックアンジオを用いた、脳動脈瘤内の血流速さ測定法の開発(第一報)

2004/09 - European Society of Neuroradiology poster prize ステントのストラッド径、ストラッド、effective postioningが脳動脈瘤内の血流に与える影響:有限要素法による解析

2003/11 - 第19回日本脳血管内治療年学会 Silver Prize The 19th annual meeting of The Japanese Society for Intravascular Neurosurgery ステントのセルデザインが脳動脈瘤内の血流に与える影響:有限要素法による解析

2002/06 - 14th Society of International Latin America Neuroradiology Dr. Fernando Vinuela prize ステントが脳動脈瘤内の血流に与える影響

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Association Membership(s) (3)：

JAPANESE SOCIETY OF BIORHEOLOGY , JAPANESE SOCIETY FOR MEDICAL AND BIOLOGICAL ENGINEERING , THE JAPAN SOCIETY OF MECHANICAL ENGINEERS

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