Okuda Tomoyuki

オクダトモユキ | Okuda Tomoyuki

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www-yaku.meijo-u.ac.jp/kenkyu/drug-deli/

Research field (1)： Medical systems

Research keywords (5)：核酸医薬 , 遺伝子治療 , 粉末粒子設計 , 吸入粉末剤 , ドラッグ・デリバリー・システム

Research theme for competitive and other funds (9)：

2024 - 2027 室温保存および吸入剤応用に適したmRNA粉末製剤化技術の基盤構築
2021 - 2024 ウイルスベクターに適した粉末製剤設計による経肺・経鼻投与型遺伝子吸入粉末剤の開発
2017 - 2020 Comprehensive investigations on development, biodistribution, and safety of nanoparticle-loaded dry powder formulations for inhalation with high nanoparticle redispersibility and aerosol performance
2014 - 2018 Development of Novel Dry siRNA Powders for Inhalation Based on Spontaneous Lipid Nanoparticle Constitution in Lung
2011 - 2013 Fate of siRNA in the lungs and optimization of siRNA inhalant formulation based on RNA interference effect

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Papers (62)：

Motoki Sugiura, Tomoyuki Okuda, Emina Yagi, Hirokazu Okamoto. Optimized Molecular Weight of Hydroxypropyl Cellulose in Inhaled Spray-Freeze-Dried Powders for High Deagglomeration and Pulmonary Retention Abilities. Chemical and Pharmaceutical Bulletin. 2026. 74. 1. 55-63
Motoki Sugiura, Tomoyuki Okuda, Hirokazu Okamoto. Development of an inhaled spray-freeze-dried powder composed of methyl cellulose and a dispersion enhancer for prolonged pulmonary drug retention and high aerosol performance. Journal of Pharmaceutical Sciences. 2025. 114. 9. 103907-103907
Tomoyuki OKUDA. Establishment of Fundamental Production Technique for Inhaled High-Dose Dry Powders. Hosokawa Powder Technology Foundation ANNUAL REPORT. 2025
Hirokazu Okamoto, Yuri Takeda, Tomoyuki Okuda. An in vitro analysis of pulmonary deliverability of inhalable solutions and inhalable aerosol products dispersed in ventilator circuit. Aerosol Science and Technology. 2025. 59. 4. 388-401
Takaaki Ito, Tomoyuki Okuda, Seiko Uede, Yuki Kushi, Kohei Tahara, Hirokazu Okamoto. Development of naked pDNA inhalation powder formulation with high transfection efficiency using hyaluronic acid and phenylalanine as excipients. Advanced Powder Technology. 2025. 36. 1. 104750-104750

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MISC (6)：

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Patents (2)：

Books (4)：

Education (3)：

Professional career (1)：

Work history (3)：

Awards (2)：

Association Membership(s) (4)：

粉体工学会 , 日本DDS学会 , 日本薬剤学会 , 日本薬学会

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