Rchr
J-GLOBAL ID:200901040167613799   Update date: Apr. 24, 2024

Uchiumi Fumiaki

ウチウミ フミアキ | Uchiumi Fumiaki
Research field  (1): Pharmaceuticals - health and biochemistry
Research theme for competitive and other funds  (6):
  • 2012 - 2016 Biological significance of the duplicated GGAA-motifs in the human TATA-less gene promoters
  • 2000 - 2001 ウイルス遺伝子転写抑制エレメントに結合する因子のcDNAクローニング
  • 1994 - 1996 Molecular mechanisms and function of apoptosis Faculty of Pharmaceutical Science
  • 1995 - 1995 アポトーシスを司るエンドヌクレアーゼの構造と機能
  • 1993 - 種々のヒト体細胞遺伝子プロモーター領域の解析
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Papers (68):
  • Arakawa J, Kondoh H, Matsushita T, Ogino Y, Asai M, Tanuma SI, Uchiumi F. Induction of the human CDC45 gene promoter activity by natural compound trans-resveratrol. Mol Med Rep. 2024. 29. 6. 92
  • Yutaka Takihara, Ryuji Otani, Takuro Ishii, Shunsuke Takaoka, Yuki Nakano, Kaori Inoue, Steven Larsen, Yoko Ogino, Masashi Asai, Sei-ichi Tanuma and Fumiaki Uchiumi. Characterization of the human IDH1 gene promoter. AIMS Molecular Science. 2023. 10. 3. 186-204
  • Natsumi Ogawa, Shingo Nakajima, Kenya Tamada, Natsuki Yokoue, Haruki Tachibana, Miwa Okazawa, Takahiro Oyama, Hideaki Abe, Hiroaki Yamazaki, Atsushi Yoshimori, et al. Trimebutine suppresses Toll-like receptor 2/4/7/8/9 signaling pathways in macrophages. Archives of biochemistry and biophysics. 2021. 711. 109029-109029
  • Miwa Okazawa, Takahiro Oyama, Hideaki Abe, Hiroaki Yamazaki, Atsushi Yoshimori, Mitsutoshi Tsukimoto, Kazumi Yoshizawa, Koichi Takao, Yoshiaki Sugita, Takanori Kamiya, et al. A 3-styrylchromone converted from trimebutine 3D pharmacophore possesses dual suppressive effects on RAGE and TLR4 signaling pathways. Biochemical and Biophysical Research Communications. 2021. 566. 1-8
  • Akira Sato, Yoko Ogino, Sei-ichi Tanuma, Fumiaki Uchiumi. Human microRNA hsa-miR-15b-5p targets the RNA template component of the RNA-dependent RNA polymerase structure in severe acute respiratory syndrome coronavirus 2. Nucleosides, Nucleotides & Nucleic Acids. 2021. 1-8
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MISC (19):
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Books (25):
  • Bidirectional Gene Promoters-Transcription System and Chromosomal Structure, 1st ed.
    Elsevier, USA 2022 ISBN:9780128187876
  • Gene Expression (Ed. Fumiaki Uchiumi)
    IntechOPEN Limited (London) 2022 ISBN:9781803556215
  • Chapter 1 “Introductory Chapter: Gene Expression in Eukaryotic Cells” in "Gene Expression" (Ed. Fumiaki Uchiumi)
    IntechOPEN Limited (London) 2022 ISBN:9781803556222
  • Advances in Medicine and Biology, Vol. 159
    Nova Science Publishers, Inc., Hauppauge, NY 2020 ISBN:9781536171846
  • Gene Expression and Control (Ed. Fumiaki Uchiumi)
    IntechOPEN Limited (London) 2019 ISBN:9781789855173
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Lectures and oral presentations  (241):
  • ヒトSP1遺伝子5’-上流のプロモーター活性の解析
    (第67回日本薬学会関東支部大会 2023)
  • ヒトEP300遺伝子プロモーターのレスベラトロールと酪酸に対する応答性の解析
    (第67回日本薬学会関東支部大会 2023)
  • 酪酸菌(Clostridium butyricum TO-A)培養上清のヒトDNA修復関連遺伝子プロモーターに対する効果
    (第46回日本基礎老化学会大会 2023)
  • 双方向遺伝子プロモーター
    (2023年度日本生化学会関東支部例会 2023)
  • Effect of the natural compound trans-resveratrol on human MCM4 gene transcription
    (BIT's 9th Annual World Congress of Food and Nutrition-2023 2023)
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Education (3):
  • 1989 - 1993 The University of Tokyo Graduate School, Division of Medical Sciences
  • 1987 - 1989 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
  • 1983 - 1987 Tokyo University of Science Faculty of Science Chemistry
Professional career (2):
  • Ph.D (Medical Science) (The University of Tokyo)
  • Ph.D (Pharmaceutical Science) (Tokyo University of Science)
Committee career (1):
  • 2023/04/01 - 2025/03/31 日本基礎老化学会 評議員
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