Kuwae Asaomi

クワエアサオミ | Kuwae Asaomi

Affiliation and department：
Job title： Associate Professor

Research field (1)： Bacteriology

Research keywords (3)： Medical Bacteriology , 細菌学 , Bacteriology

Research theme for competitive and other funds (13)：

2020 - 2023 Molecular mechanisms of cell death induced by BteA family proteins
2019 - 2023 新たな百日咳ワクチンの開発に向けて-外膜ベシクルと宿主細胞の相互作用
2017 - 2020 Molecular mechanisms of necrosis induced by BteA family proteins
2014 - 2017 Analyses of the functions of Bordetella BopC that induce actin-dependent necrotic cell death.
2013 - 2015 Dual effector BspR that functions in Bordetella and host cells

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Papers (39)：

Yoshihiro Watanabe, Takeshi Haneda, Aoi Kimishima, Asaomi Kuwae, Takuya Suga, Takahiro Suzuki, Yoshiharu Iwabuchi, Masako Honsho, Sota Honma, Masato Iwatsuki, et al. PurA is the main target of aurodox, a type III secretion system inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 17. e2322363121
Yuta Kikuchi, Mariko Yoshida, Asaomi Kuwae, Yukihiro Asami, Yuki Inahashi, Akio Abe. Correlation between the spread of IMP-producing bacteria and the promoter strength of blaIMP genes. The Journal of antibiotics. 2024
Yuta Kikuchi, Hidehito Matsui, Yukihiro Asami, Asaomi Kuwae, Yuki Inahashi, Hideaki Hanaki, Akio Abe. Landscape of blaNDM genes in Enterobacteriaceae. The Journal of Antibiotics. 2022. 75. 10. 559-566
Aoi Kimishima, Daichi Hagimoto, Masako Honsho, Yoshihiro Watanabe, Masato Iwatsuki, Hayama Tsutsumi, Yuki Inahashi, Kamrun Naher, Kazunari Sakai, Asaomi Kuwae, et al. Insights into the structure-activity relationship of a type III secretion system inhibitor, aurodox. Bioorganic & medicinal chemistry letters. 2022. 69. 128779-128779
Masataka Goto, Akio Abe, Tomoko Hanawa, Masato Suzuki, Asaomi Kuwae. Bcr4 is a Chaperone for the Inner Rod Protein in the Bordetella Type III Secretion System. 2021

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MISC (13)：

Bacteriological characteristics and virulence factors of Bordetella pertussis. 2016. 60. 7. 736-741
千葉紗由利, 桑江朝臣, 久留島潤, 阿部章夫. ボルデテラ属細菌のエフェクターBopNのimportin beta-1を介した核移行メカニズムの解析. 日本分子生物学会年会プログラム・要旨集(Web). 2012. 35th
韓賢子, 蒲地一成, 桑江朝臣, 阿部章夫, 荒川宜親. 百日咳の感染制御に向けて百日咳菌タイプIIIエフェクターBopCのIS481による発現調節. 日本細菌学雑誌. 2009. 64. 1. 108-108
韓賢子, 蒲地一成, 桑江朝臣, 阿部章夫, 荒川宜親. 百日咳流行株におけるタイプIIIエフェクターBopCの発現差異について. 日本細菌学雑誌. 2008. 63. 1. 111-111
桑江朝臣, 阿部章夫. ボルデテラ属細菌のタイプIIIエフェクターBopCの機能解析. 日本細菌学雑誌. 2007. 62. 1. 112-112

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Lectures and oral presentations (9)：

ボルデテラ属細菌のタイプIII分泌機構より分泌される蛋白質の機能解析
(日本細菌学雑誌62 (2) 2007)
細菌の病原因子注入装置: TTSS
(感染・炎症・免疫 Vol. 36, No. 1 2006)
腸管病原性大腸菌の感染機構
(実験医学 Vol. 23, No. 17 2005)
Type III effectors: Sophisticated bacterial virulence factors
(COMPTES RENDUS BIOLOGIES (第328巻第5号) 2005)
細菌のIII型分泌装置とその機能
(化学療法の領域 Vol. 21, No. 5 2005)

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Professional career (2)：

Association Membership(s) (2)：

日本免疫学会 , 日本細菌学会

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