Rchr
J-GLOBAL ID:200901040326697702   Update date: Dec. 27, 2019

ISHISAKI Akira

イシサキ アキラ | ISHISAKI Akira
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://cellbiosignal.jp/
Research field  (1): Functional basic dentistry
Research keywords  (5): Periodontal Tissue ,  Cell ,  Differentiation ,  Biochemistry ,  Molecular Biology
Research theme for competitive and other funds  (29):
  • 2017 - 2020 Establishment of novel therapy for dentin regeneration by using GDF-5 and dental pulp stem cell niche
  • 2017 - 2020 Elucidation of molecular mechanism underlying EMT/MET in oral squamous cell carcinoma cells
  • 2016 - 2020 Establishment of novel functionally graded implant therapy with dental pulp stem cells
  • 2016 - 2020 Establishment of novel therapy against refractory osteonecrosis of the jaw by using myofibroblasts and progenitors of vascular endothelial cells
  • 2017 - 2019 Establishment of novel therapy against refractory osteonecrosis of the jaw by using mesenchymal stem cells-propagated M2-macrophages
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Papers (110):
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Books (4):
  • Oral Biochemistry (5th Edition)
    Ishiyaku Publishers. Inc. 2011
  • Interface oral health science 2011.
    Springer, New York 2012
  • Angiogenic capacity of periodontal ligament-derived stem cells. [Advances in oral tissue engineering. Murata M. & Um IW. (ed.)]
    Quintessence Publishing 2014
  • Oral Bioscience (6th Edition)
    Ishiyaku Publishers, Inc. 2018
Lectures and oral presentations  (64):
  • GFPマウス骨髄由来間葉系幹細胞の 分化能とサイトカイン受容体の発現
    (第140回春季日本歯科保存学会 2014)
  • TGF-β1はヒト扁平上皮癌細胞株HSC-4細胞においてMMP-10を介した浸潤能を誘導する
    (第87回日本生化学会大会 2014)
  • 赤色蛍光強発現マウス骨髄由来間葉系幹細胞と未分化血球細胞との共培養系の樹立
    (第37回日本分子生物学会年会 2014)
  • VEGFはTGF-βにより誘導される間葉系幹細胞の骨芽細胞分化を増強する
    (第87回日本生化学会大会 2014)
  • 口腔軟組織における Bisphosphonate製剤の作用に着目したBRONJ発症機序の探究
    (第87回日本生化学会大会 2014)
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Education (2):
  • 1982 - 1988 Tokyo Medical and Dental University Faculty of Dentistry
  • 1989 - 1993 Tokyo Medical and Dental University Graduate School, Division of Dental Research
Professional career (1):
  • PhD (Dentistry) (Tokyo Medical and Dental University)
Work history (8):
  • 1994 - 1997 Post-Doctoral Fellow, Ludwig Institute for Cancer Research (Upplasa Branch)
  • 1997 - 1998 Post-Doctoral Fellow, Japan Health Sciences Foundation (National Institute of Infectious Diseases)
  • 1998 - 2002 NEDO Fellow, National Institute of Advanced Industrial Science and Technology (AIST)
  • 2002 - 2003 Senior Research Scientist, AIST
  • 2003 - 2005 Instructor, Department of Pharmacology, Gifu University Graduate School of Medicine
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Committee career (14):
  • 2019/10 - 現在 Experimental and Therapeutic Medicine Editorial Board member
  • 2019/04 - 現在 Molecular Medicine Reports Editorial Board member
  • 2016/04 - 現在 Editor-in-Chief Dental Journal of Iwate Medical University
  • 2015/07 - 2017/06 The Japanese Dental Science Review Editorial Board
  • 2014/01 - 2016/12 Journal of Biochemistry Advisory Board
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Awards (1):
  • 1994 - The Fellowship from The Japan-Sweden Foundation
Association Membership(s) (9):
The Japanese Association for Oral Biology ,  The Japanese Biochemical Society ,  The Molecular Biology Society of Japan ,  The Japanese Pharmacological Society ,  The Japanese Dental Education Association ,  Hokkaido Association for Dental Science ,  Iwate Association for Dental Science ,  Japan Tissue Culture Society for Dental Research ,  The Stomatological Society, Japan
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