Rchr
J-GLOBAL ID:200901040410896435   Update date: Sep. 04, 2020

Kobayashi Tsuneo

コバヤシ ツネオ | Kobayashi Tsuneo
Affiliation and department:
Job title: Associate Professor
Other affiliations (1):
Research field  (4): Anatomy ,  Physiology ,  Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (23): マイクロパーティクル ,  細胞外小胞 ,  活性酸素 ,  血管内皮細胞 ,  糖尿病 ,  遺伝子発現 ,  アンジオテンシン ,  酸化ストレス ,  血管障害 ,  ノンスリン ,  循環 ,  インスリン抵抗 ,  インスリン抵抗性 ,  EDHF ,  エンドセリン-1 ,  PPARα ,  アディポサイトカイン ,  内皮細胞 ,  cyclic AMP ,  インスリン ,  NAD(P)Hoxidase ,  血管 ,  diabetes vascular
Research theme for competitive and other funds  (2):
  • 糖尿病性血管合併症の研究
  • Endothelial dysfunction in diabetic animal models
Papers (135):
  • Takayuki Matsumoto, Mihoka Kojima, Keisuke Takayanagi, Tomoki Katome, Kumiko Taguchi, Tsuneo Kobayashi. Amplification of the COX/TXS/TP receptor pathway enhances uridine diphosphate-induced contraction by advanced glycation end products in rat carotid arteries. Pflügers Archiv - European Journal of Physiology. 2019. 471. 11-12. 1505-1517
  • Kumiko Taguchi, Nanami Bessho, Nozomu Kaneko, Kanami Okudaira, Takayuki Matsumoto, Tsuneo Kobayashi. Glucagon-like peptide-1 increased the vascular relaxation response via AMPK/Akt signaling in diabetic mice aortas. European Journal of Pharmacology. 2019. 865. 172776-172776
  • Takayuki Matsumoto, Keisuke Takayanagi, Mihoka Kojima, Tomoki Katome, Kumiko Taguchi, Tsuneo Kobayashi. Direct Impairment of the Endothelial Function by Acute Indoxyl Sulfate through Declined Nitric Oxide and Not Endothelium-Derived Hyperpolarizing Factor or Vasodilator Prostaglandins in the Rat Superior Mesenteric Artery. Biological and Pharmaceutical Bulletin. 2019. 42. 7. 1236-1242
  • Takayuki Matsumoto, Keisuke Takayanagi, Shota Kobayashi, Mihoka Kojima, Kumiko Taguchi, Tsuneo Kobayashi. Effect of Equol on Vasocontractions in Rat Carotid Arteries Treated with High Insulin. Biological and Pharmaceutical Bulletin. 2019. 42. 6. 1048-1053
  • Kumiko Taguchi, Haruka Narimatsu, Takayuki Matsumoto, Tsuneo Kobayashi. ERK-containing microparticles from a diabetic mouse induce endothelial dysfunction. Journal of Endocrinology. 2019. 241. 3. 221-233
more...
MISC (71):
  • Takayuki Matsumoto, Shun Watanabe, Kumiko Taguchi, Tsuneo Kobayashi. Increased Up(4)A-induced contraction in type 2 diabetic renal artery due to activated COX/thromboxane receptor axis. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 196P-196P
  • Kumiko Taguchi, Takayuki Matsumoto, Tsuneo Kobayashi, Yuichi Hattori. G protein-coupled receptor kinase 2 impairs insulin-induced Akt/eNOS signaling. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 104P-104P
  • Keiko Ishida, Takayuki Matsumoto, Tsuneo Kobayashi. Pravastatin normalizes endothelium-derived contracting factor (EDCF)-induced response by suppression of Rho-kinase signalling in superior mesenteric artery from aged type 2 diabetic rat. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 242P-242P
  • Takayuki Matsumoto, Shingo Nemoto, Kumiko Taguchi, Katsuo Kamata, Tsuneo Kobayashi. Involvement of CaM kinase II in impairments of endothelial function and eNOS activity in aortas of type 2 diabetic Goto-Kakizaki rats. FASEB JOURNAL. 2012. 26
  • Takayuki Matsumoto, Kumiko Taguchi, Katsuo Kamata, Tsuneo Kobayashi. Insulin-mediated Akt/eNOS signaling is defective in ob/ob mouse aorta due to negative regulation by translocated GRK2. FASEB JOURNAL. 2012. 26
more...
Education (1):
  • - 2000 Hoshi University
Professional career (1):
  • 薬学博士 (星薬科大学)
Work history (3):
  • 2015 - 現在 Hoshi University Hoshi University
  • 2001 - 現在 Hoshi University
  • 2000 - 2001 国立医薬品食品衛生研究所
Committee career (5):
  • - 現在 日本平滑筋学会 学術評議委員
  • 2013/04 - 2016/03 日本薬学会 編集委員
  • 2015 - 2016 日本薬理学会 年会組織委員
  • 2013 - 2013 日本平滑筋学会 総会事務長
  • 日本薬理学会 学術評議委員
Awards (7):
  • 2020/04 - The Most Published Author Award 2015-2019 in Biological and Pharmaceutical Bulletin (BPB)
  • 2009 - 日本平滑筋学会 優秀演題賞
  • 2008 - 日本平滑筋学会 ベストダウンロード賞
  • 2007 - 日本平滑筋学会 ベストダウンロード賞
  • 2007 - 日本薬学会関東支部 奨励賞
Show all
Association Membership(s) (11):
日本健康医療学会 ,  PHYSIOLOGICAL SOCIETY OF JAPAN ,  日本くすりと糖尿病学会 ,  American Physiological Society ,  日本心脈管作動物質学会 ,  日本糖尿病・肥満動物学会 ,  日本循環薬理学会 ,  日本平滑筋学会 ,  日本糖尿病学会 ,  日本薬学会 ,  日本薬理学会
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