Rchr
J-GLOBAL ID：200901040711421980   Update date: May. 25, 2025

Toshihiko Torigoe

トリゴエ トシヒコ | Toshihiko Torigoe
Affiliation and department：
Sapporo Medical University Graduate School of Medicine

About Sapporo Medical University Graduate School of Medicine


Job title： Professor
Homepage URL  (1)： http://web.sapmed.ac.jp/patho1/research/report02.html
Research field  (5)： Experimental pathology ,  Cell biology ,  Human pathology ,  Tumor diagnostics and therapeutics ,  Tumor biology
Research keywords  (5)： Autoimmunity, Autoantibody, Inflammation ,  Cancer Stem Cell, Oncogene, Tumor Suppressor ,  Immunopathology, Human Pathology ,  Cellular Stress Response, Heat Shock Protein, Molecular Chaperone ,  Cancer Immunity, Immunotherapy, Vaccine, T-cell Therapy
Research theme for competitive and other funds  (36)：
  • 2024 - 2027 Elucidation of the mechanism of resistance acquisition in 1st/2nd line treatment for metastatic breast cancer focusing on ESR1 mutations
  • 2023 - 2026 A study of computer aided diagnosis system of cervical cytology using deep learning.
  • 2021 - 2025 Comprehensive analysis of T-cell receptor ligand by using pHLA multimer library
  • 2020 - 2023 development of combined immunotherapy targeting ero1 in triple negative breast cancer
  • 2020 - 2023 乳癌の転移巣を伴うリンパ節内のT-cellにおける免疫応答
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Papers (432)：
  • Hazuki Kashiwagi, Kengo Shigehara, Terufumi Kubo, Yoshihiko Hirohashi, Tasuku Mariya, Kazuhiko Matsuo, Tomoyuki Minowa, Shin-Ichi Ishioka, Kenji Murata, Takayuki Kanaseki, et al. Large number of CD68+/CD163+ Hofbauer cells and characteristic vascular structural alterations in the placental villi of cases with placenta accreta spectrum. Medical molecular morphology. 2025
  • Keigo Moniwa, Serina Tokita, Toshiyuki Sumi, Hiroshi Saijo, Shintaro Sugita, Kotomi Arioka, Yoshihiko Hirohashi, Hirofumi Chiba, Takayuki Kanaseki, Toshihiko Torigoe. Loss of Tapasin in Tumors Potentiates T-Cell Recognition and Anti-Tumor Effects of Immune Checkpoint Blockade. Cancer science. 2025
  • Nanako Kikuchi, Sae Hatanaka, Terufumi Kubo, Ryuta Kamekura, Masatoshi Kanda, Takuya Kakuki, Takashi Sasaya, Kengo Mita, Hiroki Kobayashi, Hajime Ikai, et al. Characteristic TARC/CCL17 expression in the salivary gland of IgG4-related disease: potential diagnostic utility and insights into pathogenesis. Immunological medicine. 2025. 1-7
  • Kanta Hori, Shuhei Yamada, Kenji Murata, Haruka Miyata, Yuka Mizue, Aiko Murai, Tomoyuki Minowa, Kenta Sasaki, Naoki Shijubou, Terufumi Kubo, et al. Establishment of potent TCR-T cells specific for cisplatin-resistance related tumor-associated antigen, CLSPN using codon-optimization. Human vaccines & immunotherapeutics. 2024. 20. 1. 2414542-2414542
  • Minami Fusagawa, Serina Tokita, Kenji Murata, Tasuku Mariya, Mina Umemoto, Shintaro Sugita, Kazuhiko Matsuo, Yoshihiko Hirohashi, Tsuyoshi Saito, Takayuki Kanaseki, et al. Identification and phenotypic characterization of neoantigen-specific cytotoxic CD4+ T cells in endometrial cancer. Cancer Immunology Research. 2024
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MISC (288)：
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Patents (56)：
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Education (1)：
  • 1978 - 1984 National Defense Medical College Medical Science
Professional career (1)：
  • M.D., Ph.D.
Work history (10)：
  • 2015/10 - 現在 Sapporo Medical University Graduate School of Medicine Professor
  • 2015/10 - 現在 Sapporo Medical University School of Medicine Medical Sciences Professor
  • 2004/10 - 2015/10 Sapporo Medical University Graduate School of Medicine Associate Professor
  • 1997/11 - 2015/10 Sapporo Medical University School of Medicine Medical Sciences Assistant Professor and Associate Professor
  • 1993/08 - 1997/11 Japan Self Defense Force Sapporo General Hospital Division of Surgical Pathology Pathologist
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Awards (11)：
  • 2025/04 - The Japanese Society of Pathology The Japanese Society of Pathology Awards Fundamental Research on Immune Response to Cancer and Its Therapeutic Application
  • 2023/02 - Hokkaido Prefecture Hokkaido Scientific Technology Prize
  • 2022/09 - The Akiyama Life Science Foundation The Akiyama Foundation Prize
  • 2014 - Ono Cancer Research Foundation Research Grant
  • 2014 - NOASTEC Foundation Research and Development Grant
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Association Membership(s) (7)：
日本宇宙生物学会 ,  Cell Stress Society International ,  American Association for Cancer Research ,  The Japanese Society for Immunology ,  The Japanese Society of Pathology ,  The Japanese Cancer Association ,  Japanese Association of Cancer Immunology
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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