Okamoto-Katsuyama Mayumi

• TMIG  Research Center for Advanced Science and Technology 

• グルコマンナン由来オリゴ糖の酵素的生産と新規機能性の評価
• 標識エストラジオールの合成とその生体内挙動の解明
• 血糖値上昇抑制/低下作用を有する[6]-gingerol及びその類縁体の合成と生理活性評価
• New evaluation study of enzymatic production of oligosaccharides from konjac glucomannan.
• Enantio-differential approach to identify the target E2-receptor, by using fluorescence- or stable isotope- labeled probe compounds.
A new [6]-gingerol analogue protective effect with respect to the development of metabolic syndrome in mice fed a high-fat diet

• Mayumi Okamoto, Kyosuke Naka, Kiichi Ishiwata, Isao Shimizu, Jun Toyohara. Synthesis and basic evaluation of 7 alpha-(3-[F-18]fluoropropyl)-testosterone and 7 alpha-(3-[F-18]fluoropropyl)-dihydrotestosterone. ANNALS OF NUCLEAR MEDICINE. 2017. 31. 1. 53-62
• Okamoto M, Shibayama H, Naka K, Kitagawa Y, Ishiwata K, Shimizu I, Toyohara J. Optimization of the alkyl side chain length of fluorine-18-labeled 7α-alkyl-fluoroestradiol. Nuclear medicine and biology. 2016. 43. 8. 512-519
• Jun Toyohara, Mayumi Okamoto, Hiroki Aramaki, Yuto Zaitsu, Isao Shimizu, Kiichi Ishiwata. (R)-[ C-11]Emopamil as a novel tracer for imaging enhanced P-glycoprotein function. NUCLEAR MEDICINE AND BIOLOGY. 2016. 43. 1. 52-62
• Mayumi Okamoto, Kyosuke Naka, Yuya Kitagawa, Kiichi Ishiwata, Mitsuyoshi Yoshimoto, Isao Shimizu, Jun Toyohara. Synthesis and evaluation of 7 alpha-(3-[F-18]fluoropropyl) estradiol. NUCLEAR MEDICINE AND BIOLOGY. 2015. 42. 7. 590-597
• Koshi Machida, Takahiro Abe, Daisuke Arai, Mayumi Okamoto, Isao Shimizu, Nicole J. de Voogd, Nobuhiro Fusetani, Yoichi Nakao. Cinanthrenol A, an Estrogenic Steroid Containing Phenanthrene Nucleus, from a Marine Sponge Cinachyrella sp. ORGANIC LETTERS. 2014. 16. 6. 1539-1541

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• Jun Toyohara, Tetsuro Tago, Mayumi Okamoto, Kiichi Ishiwata, Kenji Ishii. Development of a novel cerebral blood flow PET tracer for diagnosis of dementia with diabetes mellitus. JOURNAL OF NUCLEAR MEDICINE. 2017. 58
• 豊原潤, 岡本真由美, 岡本真由美, 荒牧光紀, 財津優人, 清水功雄, 石渡喜一. P糖たんぱく質の機能亢進を画像化するPET薬剤としての(R)-[¹¹C]Emopamilの基礎評価. 核医学. 2015. 52. 3. 270
• 岡本真由美, 亀谷奎吾, 金田一智梨, 福永慶次郎, 清水功雄, 藤野良, 竹本克宏. 新規機能性材料としてのコンニャク由来グルコマンナンオリゴ糖の構造解析. Fragr J. 2015. 43. 6. 78-82
• 岡本 真由美, 亀谷 奎吾, 金田一 智梨. New evaluation study of enzymatic production of oligosaccharides from konjac glucomannan. Fragrance journal = フレグランスジャーナル. 2015. 43. 6. 78-82
• Jun Toyohara, Mayumi Okamoto, Hiromitsu Shibayama, Kyousuke Naka, Yuya Kitagawa, Kiichi Ishiwata, Isao Shimizu. Structure activity relationships of F-18-labeled 7 alpha-alkyl-estradiol derivatives. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2015. 58. S191-S191

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• Waseda University
• Kyoto University
• WASEDA Graduate School, Division of Science and Engineering Bioscience and Biomedical Engineering
• KYOTO Graduate School, Division of Medicine

• Doctor of Science (Waseda University)

• 2021/04 - 現在 The University of Tokyo Research Center for Advanced Science and Technology

日本生化学会 ,  日本神経病理学会 ,  日本農芸化学会 ,  米国神経化学会 ,  日本安定同位体・生体ガス医学応用学会 ,  公益社団法人 日本薬理学会 ,  日本ケミカルバイオロジー学会 ,  The Japanese Biochemical Society ,  The Japanese Society of Neuropathoology ,  and Agrochemistry ,  Biotechnology ,  Japan Society for Bioscience ,  American Society for Neurochemistry ,  Japan Society for Medical Application of Stable Isotope and Biogas ,  The Japanese of Pharmacological Society ,  Japanese Society for Chemical Biology