Ishimoto Kenji

イシモトケンジ | Ishimoto Kenji

Affiliation and department：
Job title： Specially Appointed Associate Professor
Other affiliations (1)：

(兼)大阪大学国際医工情報センター特任講師(常勤)

Homepage URL (1)： http://www.phs.osaka-u.ac.jp/homepage/b025/

Research field (2)： Clinical pharmacy , Pharmaceuticals - health and biochemistry

Research keywords (8)：機能性食品 , 転写因子 , 食品科学 , 薬物動態 , Lipin1 , 遺伝子発現解析 , 脂質代謝 , 核内受容体

Research theme for competitive and other funds (7)：

2021 - 2024 持続可能な超高齢化社会を実現する認知症に対する予防医療戦略の基盤構築
2020 - 2023 Preparation and evaluation of amorphous of poorly water-soluble polyphenols for prevention of NAFLD / NASH
2018 - 2021 Development of NASH therapeutics by regulating energy expenditure and inflammation through the lipid sensor PPAR
2015 - 2018 Analysis of the transcriptional regulatory mechanism of nuclear receptors via posttranslational modification of the nuclear receptors and localization of the interacting factors
2014 - 2016 The search of novel factors that control the subcellular localization of Lipin1

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Papers (37)：

Kenji Ishimoto, Yuma Konishi, Shuichi Otani, Soya Maeda, Yukio Ago, Nobumasa Hino, Masayuki Suzuki, Shinsaku Nakagawa. Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy. Journal of natural medicines. 2023. 77. 3. 604-609
河本茉侑, 石本憲司, 金子瑞季, 樋野展正, 中川晋作. 機能性食品開発を目指した非晶質化β-カロテンの機能性評価. 日本DDS学会学術集会プログラム予稿集. 2022. 38回. 114-114
Kenji Ishimoto, Yukiko Shimada, Akane Ohno, Shuichi Otani, Yukio Ago, Soya Maeda, Bangzhong Lin, Kazuto Nunomura, Nobumasa Hino, Masayuki Suzuki, et al. Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion. Frontiers in Nutrition. 2022. 9
山口拓海, 片平海雅, 山口稜太, 石本憲司, 樋野展正, 高垣昌子, 大木渉吾, 鈴木壯幸, 中川晋作, 吾郷由希夫. 緑茶カテキン代謝物EGC-M5はマウスの認知機能障害と抑うつ様行動を軽減する. 日本薬学会年会要旨集. 2022. 142年会. 26L-am08S
Kotaro Sakamoto, Lu Chen, Tatsunori Miyaoka, Mei Yamada, Teruaki Masutani, Kenji Ishimoto, Nobumasa Hino, Shinsaku Nakagawa, Satoshi Asano, Yukio Ago. Generation of KS-133 as a Novel Bicyclic Peptide with a Potent and Selective VIPR2 Antagonist Activity that Counteracts Cognitive Decline in a Mouse Model of Psychiatric Disorders. Frontiers in pharmacology. 2021. 12. 751587-751587

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MISC (70)：

山口拓海, 片平海雅, 山口稜太, 石本憲司, 石本憲司, 樋野展正, 樋野展正, 高垣昌子, 大木渉吾, 鈴木壯幸, et al. EGC-M5, a green tea catechin metabolite, alleviates cognitive deficits and depressive-like behaviors in mice. 日本薬学会年会要旨集(Web). 2022. 142nd
河本茉侑, 石本憲司, 石本憲司, 金子瑞季, 樋野展正, 中川晋作, 中川晋作, 中川晋作. 機能性食品開発を目指した非晶質化β-カロテンの機能性評価. 日本DDS学会学術集会プログラム予稿集. 2022. 38th
石本憲司, 石本憲司, 中川晋作, 中川晋作. Preparation and evaluation of amorphous β-carotene for the development of functional foods. 日本薬学会年会要旨集(Web). 2021. 141st
小西佑磨, 石本憲司, 石本憲司, 大植颯, 大谷修一, 大谷修一, 前田壮矢, 前田壮矢, 吾郷由希夫, 吾郷由希夫, et al. Basic study on the anti-allergic effect of the tea-derived material epigallocatechin gallate. 日本薬学会年会要旨集(Web). 2021. 141st
古庵大地, 今戸瑛二, 浅野智志, 浅野智志, CHEN Lu, 宮岡辰典, 山田めゐ, 石本憲司, 石本憲司, 中川晋作, et al. Neuron-specific VPAC2 receptor overexpression leads to cognitive impairment in mice. 日本薬学会年会要旨集(Web). 2021. 141st

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Patents (3)：

ピラゾロピリジン誘導体およびその使用
非晶質固体分散体、その製造方法、ならびにそれを用いた飲食品および脳内アセチルコリン濃度上昇剤
非晶質化製剤の製造方法

Education (3)：

2003 - 2006 Osaka University Graduate School of Pharmaceutical Sciences
2001 - 2003 Hokkaido University
1997 - 2001 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy

Professional career (1)：

博士(薬学) (大阪大学)

Work history (2)：

2018/06 - 現在 Osaka University
2017/09 - 現在 Osaka University Graduate School of Pharmaceutical Sciences, Drug Innovation Center

Awards (1)：

2010 - 日本薬学会近畿支部奨励賞受賞

Association Membership(s) (4)：

THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM , THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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