Tohoku University Graduate School of Medicine United Centers for Advanced Research and Translational Medicine Center for Cancer Research Cell proliferation
About Tohoku University Graduate School of Medicine United Centers for Advanced Research and Translational Medicine Center for Cancer Research Cell proliferation
2003 - 2004 Analysis of the PKC-δ Signaling Pathway by Proteomics with Embryonic and Genetic Engeneering
2003 - 2004 プロテアソームへのユビキチン化基質のターゲッテング機構の解析
2003 - 2004 Study of molecular mechanisms of CD4 silencing and role s of Runx proteins during lymphocyte development
2003 - 2003 サイクリンEのユビキチンリガーゼCdc4が細胞周期進行に果たす役割
2002 - 2003 リボザイムを用いた組織特異的ノックアウトマウス作製法の開発
2002 - 2003 マウスGemininの発生工学的手法を用いた機能解析
2002 - 2002 プロテアソームへのユビキチン化基質のターゲッテング機構の解析
2002 - 2002 2種類のサイクリンE分解機構の細胞周期進行における役割
2001 - 2002 Establishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteinsEstablishment of therapeutic method for neurodegenerative diseases by specific protein degradation system for abnormal proteins
2001 - 2002 New cancer therapy by degradation of specific proteins
2001 - 2002 New clearance system of abnormal protein in Polyglutammine disease
2001 - 2001 中心体過剰複製と染色体倍数性異常の発がんにおける役割の研究
2000 - 2001 Functional analysis of ubiquitin ligase by knock-out mise
2000 - 2000 Cyclin E過剰蓄積とp27の欠損を伴うマウスを用いた発がん機構の研究
1999 - 2000 Identification of the factors mediating ubiquitination of inclusion body in neurodegenerative diseases
1997 - 1998 Analysis of sinnalling pathway of apoptosis degradation using PKCδ gene-targeting mice
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Papers (275):
Rumiko Izumi, Kensuke Ikeda, Tetsuya Niihori, Naoki Suzuki, Matsuyuki Shirota, Ryo Funayama, Keiko Nakayama, Hitoshi Warita, Maki Tateyama, Yoko Aoki, et al. Nuclear pore pathology underlying multisystem proteinopathy type 3-related inclusion body myopathy. Annals of clinical and translational neurology. 2023
Yukimune Okubo, Moriei Shibuya, Haruhiko Nakamura, Aritomo Kawashima, Kaori Kodama, Wakaba Endo, Takehiko Inui, Noriko Togashi, Yu Aihara, Matsuyuki Shirota, et al. Neonatal developmental and epileptic encephalopathy with movement disorders and arthrogryposis: A case report with a novel missense variant of SCN1A. Brain & development. 2023
Daiki X. Sato, Yuki Matsuda, Nisikawa Usio, Ryo Funayama, Keiko Nakayama, Takashi Makino. Genomic adaptive potential to cold environments in the invasive red swamp crayfish. iScience. 2023. 107267-107267
Zhiqian Yu, Kazuko Ueno, Ryo Funayama, Mai Sakai, Naoki Nariai, Kaname Kojima, Yoshie Kikuchi, Xue Li, Chiaki Ono, Junpei Kanatani, et al. Sex-Specific Differences in the Transcriptome of the Human Dorsolateral Prefrontal Cortex in Schizophrenia. Molecular neurobiology. 2022. 60. 2. 1083-1098
Yu Aihara, Matsuyuki Shirota, Atsuo Kikuchi, Yu Katata, Yu Abe, Tetsuya Niihori, Ryo Funayama, Keiko Nakayama, Yoko Aoki, Shigeo Kure. A novel variant in the transmembrane 4 domain of ANO3 identified in a two-year-old girl with developmental delay and tremor. Journal of human genetics. 2022
中野智太, 森谷邦彦, 菊池敦生, 新妻秀剛, 笹原洋二, 舟山亮, 中山啓子, 城田松之, 新堀哲也, 青木洋子, et al. Molecular pathogenesis in two cases of IMAGE-I syndrome with novel POLE mutations. 日本免疫不全・自己炎症学会雑誌(Web). 2023. 2. 2
An Amyotrophic Lateral Sclerosis-Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO3
(31ST INTERNATIONAL SYMPOSIUM ON ALS/MND 2020)