Chikamatsu Kazuaki

CHIKAMATSU KAZUAKI | Chikamatsu Kazuaki

Affiliation and department：
Job title： Professor

Research field (1)： Otorhinolaryngology

Research keywords (2)：頭頸部腫瘍 , Head and Neck Cancer

Research theme for competitive and other funds (13)：

2020 - 2024 HPV-related head and neck cancer: immunological analysis and cancer immunotherapy
2017 - 2020 Exploration of molecular targets to regulate cancer-associated fibroblasts-mediated immunosuppression in the tumor microenvironment
2014 - 2017 Radiation induced immunomodulatory effects in head and neck cancers
2011 - 2013 Development of therapeutic strategies targeting epigenetics in cancer stem cells
2008 - 2010 Clinical usefulness and application of Taxol-resisitance molecules

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Papers (115)：

Momoka Horikawa, Kei Masuda, Hideyuki Takahashi, Hiroe Tada, Yuichi Tomidokoro, Masaomi Motegi, Tetsunari Oyama, Shigeki Takeda, Kazuaki Chikamatsu. Tumor antigen-specific interleukin-10-producing T-cell response in patients with head and neck squamous cell carcinoma. Oncology Letters. 2024
Kazuaki Chikamatsu, Shota Ida, Kei Masuda, Momoka Horikawa, Nanami Hoshino, Hideyuki Takahashi, Hiroe Tada, Tetsunari Oyama, Shigeki Takeda, Yuichi Tomidokoro, et al. Enhancement of Tumor Antigen-specific T-cell Responses by Immune Checkpoint Blockade in Human Papillomavirus-related Head and Neck Squamous Cell Carcinoma. Anticancer research. 2024. 44. 7. 2921-2931
Atsushi Musha, Nobuteru Kubo, Hidemasa Kawamura, Naoko Okano, Hiro Sato, Kohei Okada, Kento Tomizawa, Norichika Ota, Akiko Adachi, Masato Shino, et al. Efficacy of immune checkpoint inhibitor treatment for head and neck mucosal melanoma recurrence in patients treated with carbon-ion radiotherapy. Cancer reports (Hoboken, N.J.). 2023. 6. 7. e1825
Ikko Mito, Hideyuki Takahashi, Reika Kawabata-Iwakawa, Momoka Horikawa, Shota Ida, Hiroe Tada, Toshiyuki Matsuyama, Kiyoshi Misawa, Shigeki Takeda, Kazuaki Chikamatsu. Tumor-derived exosomes elicit cancer-associated fibroblasts shaping inflammatory tumor microenvironment in head and neck squamous cell carcinoma. Oral oncology. 2023. 136. 106270-106270
Naoto Osu, Atsushi Musha, Hikaru Yumisaki, Kohei Okada, Nobuteru Kubo, Naoko Okano, Yukihiko Takayasu, Masato Shino, Osamu Nikkuni, Shota Ida, et al. The Efficacy of Radiotherapy without Surgery for External Auditory Canal Squamous Cell Carcinoma. Journal of Clinical Medicine. 2022. 11. 19. 5905-5905

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MISC (219)：

山田佳苗, 立松謙一郎, 瀬筒秀樹, 近松一朗, 武田茂樹. トランスジェニックカイコで発現させたがん抗原によるがん免疫療法への応用. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
Kazuaki Chikamatsu, Hiroe Tada. A new blood test for head and neck cancers: Liquid biopsy. Practica Oto-Rhino-Laryngologica. 2019. 112. 7. 415-421
Yoko Motokawa, Michifumi Kokubo, Nobuo Kuwabara, Ken-Ichiro Tatematsu, Hideki Sezutsu, Hideyuki Takahashi, Koichi Sakakura, Kazuaki Chikamatsu, Shigeki Takeda. Melanoma antigen family A4 protein produced by transgenic silkworms induces antitumor immune responses. Experimental and Therapeutic Medicine. 2018. 15. 3. 2512-2518
Yoko Motokawa, Michifumi Kokubo, Nobuo Kuwabara, Ken-Ichiro Tatematsu, Hideki Sezutsu, Hideyuki Takahashi, Koichi Sakakura, Kazuaki Chikamatsu, Shigeki Takeda. Melanoma antigen family A4 protein produced by transgenic silkworms induces antitumor immune responses. Experimental and Therapeutic Medicine. 2018. 15. 3. 2512-2518
宮崎達也, 宗田真, 酒井真, 熊倉裕二, 吉田知典, 栗山健吾, 本城裕章, 原圭吾, 福地稔, 根岸明秀, et al. 食道癌術前術後管理とチーム医療の関わり. 日本消化管学会雑誌. 2018. 2. Suppl. 255-255

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Books (4)：

耳鼻咽喉科薬物療法2015 頭頸部領域の神経痛.
東京医学社 2015
II. 鼻・副鼻腔特殊な悪性腫瘍. 画像診断パーフェクトガイド読影のポイントとピットフォール
医学書院 2014
気道確保の後遺症.
東京医学社 2013
JOHNS 図でみる免疫学のABC
東京医学社 2013

Lectures and oral presentations (80)：

Alteration of cancer stem cell-like phenotype by histone deacetylase inhibitors in squamous cell carcinoma of the head and neck
(AACR Annual Meeting 2013 2013)
Therapeutic potentials of histone deacetylase inhibitors for cancer stem cell-like cell phenotype in squamous cell carcioma of the head and neck
(AHNS 2013 Annual Meeting 2013)
Biological markers as predictors of clinical outcome in adenoid cystic carcinoma of the head and neck
(AHNS 2013 Annual Meeting 2013)
Alteration of cancer stem cell-like phenotype by histone deacetylase inhibitors in squamous cell carcinoma of the head and neck
(AACR Annual Meeting 2013 2013)
Therapeutic potentials of histone deacetylase inhibitors for cancer stem cell-like cell phenotype in squamous cell carcioma of the head and neck
(AHNS 2013 Annual Meeting 2013)

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Professional career (1)：

Doctor(Medical Science) (Kumamoto University)

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