Tsukamoto Sachiko

ツカモトサチコ | Tsukamoto Sachiko

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://kumamoto-natmed.org/

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (2)：天然物化学 , Natural Products Chemistry

Research theme for competitive and other funds (48)：

2021 - 2024 セコロガニン関連天然物の樹形図型集団的全合成
2020 - 2024 Drug development of incurable diseases with versatile Egyptian natural resources
2021 - 2023 20Sプロテアソームのゲート開口を促進する革新的神経変性疾患治療戦略
2020 - 2023 Search for new p53 activating natural compounds as cancer therapeutic drugs and their functional analyses
2017 - 2020 タイにおける薬用資源の調査研究

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Papers (199)：

Yuki Hitora, Mako Hokaguchi, Yusaku Sadahiro, Takumi Higaki, Sachiko Tsukamoto. Machine Learning Accelerates Screening of Osteoclast Differentiation Inhibitors from Natural Products. Journal of natural products. 2024
Ahmed H. El-Desoky, Yuki Hitora, Yoshitomo Nishime, Yusaku Sadahiro, Teppei Kawahara, Sachiko Tsukamoto. A new linear peptide, higapeptin, isolated from the mud flat-derived fungus Acremonium persicinum inhibits mitochondrial energy metabolism. Journal of Natural Medicines. 2024
Yuki Hitora, Ahmed H. El-Desoky, Yusaku Sadahiro, Ai Sejiyama, Amiri Kinoshita, Yuji Ise, Esther D. Angkouw, Remy E. P. Mangindaan, Takumi Higaki, Sachiko Tsukamoto. Neopetromin, a Cyclic Tripeptide with a C-N Cross-Link, from the Marine Sponge Neopetrosia sp., That Causes Vacuole Fragmentation in Tobacco BY-2 Cells. Journal of Natural Products. 2024
Koyo Honda, Yuki Hitora, Sachiko Tsukamoto. Akanthomins A-C, aphidicolin analogs from a fungus Akanthomyces sp., that inhibit cell cycle. Phytochemistry. 2023. 216. 113885-113885
Ahmed H. El-Desoky, Keisuke Eguchi, Ippei Kagiyama, Yuki Hitora, Hikaru Kato, Yuji Ise, Fitje Losung, Remy E.P. Mangindaan, Sachiko Tsukamoto. Aaptocarbamates A-G, chlorinated terpene carbamates with antiosteoclastogenic activities from the marine sponge Aaptos sp. Phytochemistry. 2023. 216. 113872-113872

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MISC (41)：

貞廣優作, 人羅勇気, 本田公洋, 手島徳哉, 長野由梨子, 塚本佐知子. Discovery of fugal derived 20S proteasome activator using bioactive molecular networking. 日本薬学会年会要旨集(Web). 2024. 144th
Yuki Hitora, Sachiko Tsukamoto. The Search for Inhibitors of the Ubiquitin-proteasome System from Natural Sources by Cell-based Screening in Reporter-expressing Cells. Journal of Synthetic Organic Chemistry, Japan. 2023. 81. 11. 1073-1080
手島徳哉, 人羅勇気, 長野由梨子, 塚本佐知子. 深海環境から単離したArachnomyces属真菌由来の新規二次代謝産物の探索. 日本生薬学会年会講演要旨集. 2023. 69th
手島徳哉, 人羅勇気, 長野由梨子, 塚本佐知子. Construction of the extract library of marine-derived fungi: Study on the cytotoxic metabolites of the fungus Penicillium sp. from the marine sediment. 日本薬学会年会要旨集(Web). 2023. 143rd
東内原陸, 原田大地, 松木美樹, 貞廣優作, 人羅勇気, 長野由梨子, 塚本佐知子. トリプトファンによる真菌Arthrinium arundinisの二次代謝産物の産生誘導. 日本薬学会九州山口支部大会講演要旨集(CD-ROM). 2023. 40th

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Patents (4)：

Books (7)：

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Lectures and oral presentations (290)：

硝酸ナトリウムにより産生誘導された糸状菌Fusarium lateritium由来の環状ペプチドの構造
(日本生薬学会第70回年会 2024)
アカデミアにおける生薬学・天然物化学研究について〜人との出会い・化合物との出会い〜
(日本生薬学会第70回年会 2024)
分子ネットワーク解析を用いたミトコンドリア活性化天然物の探索
(第66回天然有機化合物討論会 2024)
Colletofragarone A2 from the fungus Colletotrichum sp. promoted the degradation and aggregation of mutant p53
(International Congress on Natural Products Research (ICNPR) 2024 2024)
縁と運と情熱が切り拓く天然物化学研究〜最近の研究成果から〜
(第16回化学生態学研究会 2024)

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Work history (12)：

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Committee career (13)：

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Awards (7)：

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Association Membership(s) (6)：

アメリカ生薬学会 , がん分子標的治療学会 , アメリカ化学会 , 日本化学会 , 日本生薬学会 , 日本薬学会

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