Sasaki Yuki

ササキユキ | Sasaki Yuki

Affiliation and department：
Other affiliations (1)：

Research field (4)： Immunology , Allergies and connective tissue disease , Experimental pathology , Parasitology

Research keywords (3)：免疫プロテアソーム , インフラマソーム , 自己炎症

Research theme for competitive and other funds (3)：

2022 - 2025 免疫プロテアソームの機能異常による自己炎症病態誘導機構の解析
2019 - 2022 Analysis of the mechanism of autoinflammatory disorder induction due to proteasome dysfunction
2016 - 2019 Analysis of the mechanism of autoinflammatory disorder induction due to proteasome dysfunction

Papers (18)：

Thiranut Jaroonwitchawan, Hideki Arimochi, Yuki Sasaki, Chieko Ishifune, Hiroyuki Kondo, Kunihiro Otsuka, Shin-ichi Tsukumo, Koji Yasutomo. Stimulation of the farnesoid X receptor promotes M2 macrophage polarization. Frontiers in Immunology. 2023. 14
Yuki Sasaki, Hideki Arimochi, Kunihiro Otsuka, Hiroyuki Kondo, Shin-Ichi Tsukumo, Koji Yasutomo. Blockade of the CXCR3/CXCL10 axis ameliorates inflammation caused by immunoproteasome dysfunction. JCI insight. 2022. 7. 7
Michittra Boonchan, Hideki Arimochi, Kunihiro Otsuka, Tomoko Kobayashi, Hisanori Uehara, Thiranut Jaroonwitchawan, Yuki Sasaki, Shin-Ichi Tsukumo, Koji Yasutomo. Necroptosis protects against exacerbation of acute pancreatitis. Cell death & disease. 2021. 12. 6. 601-601
Yuki Sasaki, Kunihiro Otsuka, Hideki Arimochi, Shin Ichi Tsukumo, Koji Yasutomo. Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation. Frontiers in Immunology. 2020. 11
Kazumi Okamura, Akiko Kitamura, Yoshiteru Sasaki, Doo Hyun Chung, Shoji Kagami, Kazuhiro Iwai, Koji Yasutomo. Survival of mature T cells depends on signaling through HOIP. SCIENTIFIC REPORTS. 2016. 6. 36135

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MISC (9)：

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Lectures and oral presentations (21)：

Dysregulation of immune cells by impaired functions of proteasomes
(2023)
Blockade of the CXCR3-CXCL10 axis ameliorates inflammatory responses caused by immunoproteasome dysfunctions
(2021)
Deficiency in Ripk3 or Mlkl exacerbates acute pancreatitis with increased apoptosis of acinar cell
(2021)
NLRC4ミスセンス変異誘導性関節炎の解析
(第三回日本骨免疫学会 2017)
Cytokines regulation of autoinflammation caused by dysfunctions of immunoproteasomes
(第45回日本免疫学会学術集会 2016)

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Education (3)：

Professional career (2)：

Work history (4)：

Awards (1)：

2008 - . IL-18with IL-2protects against Strongyloides venezuelensis infection by activating mucosal mast cell-dependent type 2 innate immunity.

Association Membership(s) (3)：

日本骨免疫学会 , THE JAPANESE SOCIETY OF PARASITOLOGY , THE JAPANESE SOCIETY FOR IMMUNOLOGY

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