Rchr
J-GLOBAL ID:200901043833031138
Update date: Nov. 14, 2024
Watashi Koichi
ワタシ コウイチ | Watashi Koichi
Affiliation and department:
Job title:
Director, Division of Drug Development
Other affiliations (2):
Research field (3):
Virology
, Pharmaceuticals - health and biochemistry
, Molecular biology
Research keywords (10):
HBV
, HCV
, hepatitis D virus
, coronavirus
, poxvirus
, Chemical Biology
, Anti-viral
, virus dynamics
, modality
, anti-infectives
Research theme for competitive and other funds (9):
- 2021 - 2024 Structure and functional analysis of the SARS-CoV-2 Nucleocapsid Protein
- 2020 - 2023 Molecular mechanism, dynamics, and interaction with environment in the hepatitis B virus entry system
- 2017 - 2020 Mechanistic analysis of hepatitis B virus entry and the host factors using new cell culture systems
- 2016 - 2019 Systems Virology for understanding viral pathogenesis
- 2014 - 2018 Analysis of regulation mechanisms of hepatitis B virus life cycle by kinases and post-translational modifications
- 2014 - 2016 ウイルス感染増殖系を基盤とした天然化合物新規生理機能の同定
- 2012 - 2014 肝炎ウイルス感染増殖系を用いた天然物生理活性解析
- 2011 - 2012 Mechanistic analysis of hepatitis C virus life cycle using small molecules
- 2005 - 2006 シクロスポリンを用いたC型肝炎ウイルスゲノム複製機構の解析
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Papers (229):
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Aa Haeruman Azam, Kohei Kondo, Kotaro Chihara, Tomohiro Nakamura, Shinjiro Ojima, Wenhan Nie, Azumi Tamura, Wakana Yamashita, Yo Sugawara, Motoyuki Sugai, et al. Evasion of antiviral bacterial immunity by phage tRNAs. Nature Communications. 2024. 15. 1
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Masako Yamasaki, Wakana Saso, Takuya Yamamoto, Masayoshi Sato, Hiroko Takagi, Tetsuya Hasegawa, Yuji Kozakura, Hiroyuki Yokoi, Hirofumi Ohashi, Kana Tsuchimoto, et al. Anti-SARS-CoV-2 gapmer antisense oligonucleotides targeting the main protease region of viral RNA. Antiviral research. 2024. 105992-105992
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Nozomi Mosu, Mitsuki Yasukochi, Shogo Nakajima, Kou Nakamura, Masaya Ogata, Keita Iguchi, Kazuki Kanno, Tomohiro Ishikawa, Kazutoshi Sugita, Hironobu Murakami, et al. Isolation, structural determination, and antiviral activities of a novel alanine-conjugated polyketide from Talaromyces sp. The Journal of antibiotics. 2024
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Azumi Tamura, Aa Haeruman Azam, Tomohiro Nakamura, Kenichi Lee, Sunao Iyoda, Kohei Kondo, Shinjiro Ojima, Kotaro Chihara, Wakana Yamashita, Longzhu Cui, et al. Synthetic phage-based approach for sensitive and specific detection of Escherichia coli O157. Communications Biology. 2024. 7. 1
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Hbv, Lena Allweiss, Chari Cohen, Joao Dias, Valeria Fumagalli, Haitao Guo, James M Harris, Jianming Hu, Matteo Iannacone, Masanori Isogawa, et al. Highlights from the 2023 International Meeting on the Molecular Biology of Hepatitis B virus. The Journal of general virology. 2024. 105. 5
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MISC (69):
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山下 和可奈, 小島 新二郎, アザム・アア・ハエルマン, 近藤 恒平, 中村 暢宏, 田村 あずみ, 渡士 幸一, 崔 龍洙, 常田 聡, 氣駕 恒太朗. ファージ由来溶菌酵素の殺菌力と作用域の調査. 日本細菌学雑誌. 2023. 78. 1. 148-148
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森田武志, 赤沢大輔, 日紫喜隆行, 大橋啓史, 渡士幸一. Screening and evaluation of anti-monkeypox virus using infection cell-based model. 日本薬学会年会要旨集(Web). 2023. 143rd
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小笠原諭, 赤澤大輔, 中村星王, 原田誉士, 陳思思, 渡士幸一, 村田武士. 新型コロナウイルス由来スパイクタンパク質の結合阻害をする抗ACE2モノクローナル抗体の樹立. 日本抗体学会学術大会プログラム・抄録集(Web). 2023. 2nd
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青柳東代, 飯島尋子, 若江亨祥, 渡士幸一, 鈴木亮介, 政木隆博, 政木隆博, 杉山真也, 坪田昭人, 島田紀朋, et al. C型肝炎ウイルス除去後の病態,発癌のメカニズム. 肝細胞研究会プログラム・抄録集. 2023. 30th
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深野顕人, 深野顕人, 若江亨祥, 直亨則, 直亨則, 斎藤益満, 斎藤益満, 豊嶋孝恵, 坪田昭人, 相崎英樹, et al. Development of prognostic markers for hepatocellular carcinoma using a novel detection method for hepatitis B virus DNA integration. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2023. 70th
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Professional career (2):
- Ph.D. (Kyoto University)
- Master (Pharmaceutical Sciences) (Kyoto University)
Work history (8):
- 2022/04 - 現在 (併任)早稲田大学大学院 先進理工学研究科 客員教授
- 2021/04 - 現在 National Institute of Infectious Diseases Research Center for Drug and Vaccine Development Director, Division of Drug Development
- 2019/04 - 現在 Tokyo University of Science Graduate School of Science and Technology Department of Biological Sciences (Dual Appointment) Visiting Professor
- 2009/12 - 2021/03 National Institute of Infectious Diseases Department of Virology II Senior Researcher
- 2011/04 - 2019/03 Tokyo University of Science Graduate School of Science and Technology Department of Biological Sciences (Dual Appointment) Visiting Associate Professor
- 2007/04 - 2009/11 National Institutes of Health, USA Visiting Fellow
- 2003/11 - 2008/12 Institute for Virus Research, Kyoto University Assistant Professor
- 2002/04 - 2003/10 日本学術振興会 特別研究員
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Awards (7):
Association Membership(s) (5):
THE PHARMACEUTICAL SOCIETY OF JAPAN
, Japanese Association of Antiviral Therapy
, THE JAPAN SOCIETY OF HEPATOLOGY
, 日本分子生物学会
, 日本ウイルス学会
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