Rchr
J-GLOBAL ID：200901043847764375
Update date: Sep. 27, 2024
Hayashi Yutaro
ハヤシ ユウタロウ | Hayashi Yutaro
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://www.med.nagoya-cu.ac.jp/uro.dir/
Research field (1)：
Urology
Research keywords (4)：
バイオマテリアル
, 生殖器
, 尿路
, 外因性内分泌攪乱物質
Research theme for competitive and other funds (54)：
- 2023 - 2028 1細胞RNA-sequenceを用いた停留精巣における精子幹細胞ニッチの遺伝子発現解析
- 2023 - 2027 Establishment of biomarkers of immature Sertoli cells involved in differentiation of spermatogenic stem cells and its applications for reproductive medicine
- 2023 - 2026 空間トランスクリプトーム解析による血液精巣関門の成立の解明と男性不妊治療への応用
- 2023 - 2026 幼若期の甲状腺ホルモンによる精子形成機序の解明と男性不妊症の新規治療への応用
- 2023 - 2026 Pip遺伝子を導入した培養口腔粘膜組織を用いる新規尿道下裂修復術の開発
- 2022 - 2025 機能的な構造を有する腎・尿路再生への選択的細胞抽出法を応用した基礎的研究
- 2022 - 2025 精子形成障害におけるエピゲノム因子の解明による男性不妊症に対する新規治療薬の確立
- 2021 - 2024 Comprehensive research on the roles of thyroid function involved in differentiation and proliferation of spermatogonial stem cells
- 2021 - 2024 機能改変平滑筋細胞の作製と三次元的な細胞移植による膀胱尿管逆流防止機構強化の試み
- 2020 - 2024 Comprehensive analyses of time-specific mechanisms of spermatogonial stem cell development and novel strategy for reproductive medicine
- 2019 - 2023 腎前駆細胞の選択的抽出により機能的な構造を有する腎を再生するための基礎研究
- 2018 - 2023 精巣形成不全症候群における精子幹細胞の機能異常の同定と分化機構の解明
- 2018 - 2022 Functional urotherial system reconstruction from transformed epithelial cells under flow and extension stress
- 2018 - 2022 The elucidation of the mechanism of Kdm5a, the histone-modifying enzyme, aimed at epigenetic drug discovery for testicular dysfunction
- 2017 - 2020 Comprehensive elucidation of differentiation and maturation of Sertoli cells and application to reproductive medicine
- 2017 - 2020 The elucidation of the genetic pathway of hypospadias and development of a new surgical method using a gene transferred cell sheet
- 2016 - 2019 Gene expression analysis of human spermatogonial stem cell niche using single cell RNA-sequence
- 2015 - 2018 In vivo gene transfer into the testis is an effective method for studying function of sperm protein phospholipase C zeta.
- 2015 - 2018 Elucidation of selective renal progenitor differentiation and renal regeneration mechanism using cell sorting system
- 2014 - 2017 Elucidation of characteristic alterations of spermatogonial stem cells in testicular cancer and application to genome-based drug discovery using novel cell line
- 2013 - 2016 Prevention of urolithiasis using anti-NF-kB drugs
- 2013 - 2016 Elucidation of the epigenetic regulatory network during cell differentiation of spermatogonial stem cells
- 2013 - 2016 The development of newly daiagnotic tool and treatment for male infertility in terms of spermatogonial stem cell activity
- 2012 - 2016 Genome-wide analyses of gene regulation mechanism during development of external genitalia and their clinical application
- 2012 - 2015 Analysis of the role of cyclooxygenase 2 on spermatogenesis disturbance.
- 2012 - 2015 Analysis of the nuclear receptor transcription conjugate mechanism for the hormone-resistant prostate cancer and development of the new molecular target treatment
- 2012 - 2015 Functional urotherial-sheet reconstruction from transformed epithelial cells using hollow-fiber cell-culture system
- 2012 - 2015 The investigation of the mechanism about the kidney generation using embryonic stem cells with inducible gene expression by assesment of FACS, and the application to kidney regeneration medicine
- 2012 - 2015 Etiology of testicular cancer derived from cryptorchidism and development of novel therapeutic approach targeting to spermatogonial stem cells
- 2010 - 2014 Feasibility of abnormal development of spermatogonial stem cells in impaired spermatogenesis; detection of disease genes and functional analyses
- 2010 - 2012 Anti-NF-kB reagents for prevention of urinary stone
- 2010 - 2012 Effects of chemical exposure on male reproductive organogenesis and functions
- 2009 - 2011 Functional urethral reconstruction using hollow-fiber cell-culture system
- 2009 - 2011 The Relationship between Proliferation and Maturation of Sertoli cells and Development of Male Genitalia and Spermatogenesis
- 2007 - 2008 Functional urethral reconstruction with epithelial-mesanchimal transformation and mechanical stretch of urothelial cells
- 2005 - 2007 Role of transcription factors Ad4BP/SF-1 and DAX-1 in spermatogenesis and future prospects of gene therapy for male infertility
- 2005 - 2006 Induction of Urethral Tissue Using Gene Transferred ES Cells
- 2005 - 2006 動脈硬化症との類似性からみた尿路結石症の成因の研究:特に転写因子NF-κBの関与
- 2003 - 2005 神経幹細胞および血管幹細胞から精子形成細胞への分化誘導の試み
- 2003 - 2005 The elucidation of urinary calculi formation mechanism by genome analysis
- 2003 - 2004 Functional multilayerd urethral sheet with matrix complex and its application to urethloplasty
- 2002 - 2004 減数分裂におけるDNA傷害チェックポイントの解析:染色体異常との関連から
- 2002 - 2003 The application of the transcription factor related to urinary stone formation to elucidation and gene therapy
- 2000 - 2002 外因性内分泌撹乱化学物質(環境ホルモン)の造精機能に関わる転写因子DAX-1への影響
- 1999 - 2001 Basic research in gene therapy for urolithiasis using osteopontin antisense
- 1999 - 2000 外因性内分泌攪乱物質の男子生殖器形態形成への影響:母体残留レベルを指標として
- 1997 - 1999 Disturbance of spermatogenesis and apoptosis
- 1997 - 1998 Basic research for gene therapy of urolithiasis by the inhibition of stone matrix protein
- 1996 - 1998 高度尿道下裂に対する体内各種器官を用いた尿道形成術の実験的研究
- 1996 - 1996 停留精巣・精索捻転症の造精障害(酸化ストレスとアポトーシス)に関する基礎的研究
- 1995 - 1995 尿道下裂難治症例に対する培養皮膚を用いた尿道形成術の基礎研究
- 1994 - 1995 Analyzes of Molecular Biological Mechanisms of BCG in Superficial Bladder Cancer and their Clinical Use.
- 外因性内分泌撹乱物質(環境ホルモン)による尿道および陰茎形成過程への影響
- 生殖細胞の発生・分化に関わる遺伝子の同定およびその機能解析
Show all
Papers (630)：
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Hidenori Nishio, Kentaro Mizuno, Daisuke Matsumoto, Hideyuki Kamisawa, Satoshi Kurokawa, Akihiro Nakane, Shoichiro Iwatsuki, Tetsuji Maruyama, Takahiro Yasui, Yutaro Hayashi. Evaluation of the scrotal thermal environment and the testicular sizes in prepubertal hemiscrotal agenesis without cryptorchidism. IJU case reports. 2024. 7. 5. 404-407
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Hidenori Nishio, Kentaro Mizuno, Daisuke Matsumoto, Keiichi Tozawa, Takahiro Yasui, Yutaro Hayashi. Combination of robot-assisted laparoscopic pyeloplasty for lower moiety ureteropelvic junction obstruction in a partial duplex system and percutaneous endoscopic surgery for renal calculi reusing the port for robotic pyeloplasty. IJU case reports. 2023. 6. 6. 390-393
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Hidenori Nishio, Kentaro Mizuno, Taiki Kato, Hideyuki Kamisawa, Satoshi Kurokawa, Akihiro Nakane, Tetsuji Maruyama, Noriyasu Kawai, Takahiro Yasui, Yutaro Hayashi. Surgical management of prepubertal testicular tumors: A 30-year study in our institution. International journal of urology : official journal of the Japanese Urological Association. 2023. 30. 6. 521-525
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Yohei Masunaga, Yasuko Fujisawa, Francesco Massart, Claudio Spinelli, Yoshiyuki Kojima, Kentaro Mizuno, Yutaro Hayashi, Isoji Sasagawa, Rie Yoshida, Fumiko Kato, et al. Microdeletion at ESR1 Intron 6 (DEL_6_75504) Is a Susceptibility Factor for Cryptorchidism and Hypospadias. The Journal of clinical endocrinology and metabolism. 2023. 108. 10. 2550-2560
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Hidenori Nishio, Kentaro Mizuno, Daisuke Matsumoto, Takahiro Yasui, Yutaro Hayashi. Ureterocele prolapse eliciting unusual patient behavior to control intermittent voiding. Urology case reports. 2023. 46. 102295-102295
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MISC (423)：
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加藤 大貴, 水野 健太郎, 西尾 英紀, 安井 孝周, 林 祐太郎. 思春期停留精巣モデルラットにおける血液精巣関門構成タンパクClaudin11の局在と精細胞の分化との関連. 日本小児泌尿器科学会雑誌. 2019. 28. 2. 149-149
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丸山 哲史, 加藤 大貴, 安井 孝周, 黒川 覚史, 水野 健太郎, 林 祐太郎. 尿流曲線における揺らぎと下部尿路機能障害の検討. 泌尿器科紀要. 2019. 65. 6. 231-231
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加藤 大貴, 濱本 周造, 岡田 淳志, 安井 孝周, 水野 健太郎, 西尾 英紀, 林 祐太郎. 急性胃腸炎罹患後に尿管結石嵌頓による腎後性腎不全を発症した幼児の1例. 泌尿器科紀要. 2019. 65. 6. 233-233
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加藤 大貴, 西尾 英紀, 水野 健太郎, 林 祐太郎, 河合 憲康, 安井 孝周. 膀胱原発尿路上皮癌の女児例. 日本小児血液・がん学会雑誌. 2019. 56. 1. 69-69
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岩月 正一郎, 西尾 英紀, 水野 健太郎, 梅本 幸裕, 安井 孝周, 林 祐太郎. 小児泌尿器科疾患:成育医療へのリレー 停留精巣の造精障害に対する成育医療 補助生殖医療. 日本泌尿器科学会総会. 2019. 107回. SY9-2
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Education (1)：
- - 1985 Nagoya City University Faculty of Medicine
Professional career (1)：
- 名古屋市立大学医学部/修士(医科学)・博士(医学)
Association Membership(s) (8)：
日本排尿機能学会
, 日本小児内分泌学会
, 名古屋市立大学医師会
, 愛知県泌尿器科医会
, 日本泌尿器科学会東海地方会
, 日本Endourology・ESWL学会
, 日本小児泌尿器科学会
, 日本泌尿器科学会
