Kobayashi Takehiko

コバヤシタケヒコ | Kobayashi Takehiko

Affiliation and department：
Job title：教授
Homepage URL (1)： http://lafula-com.info/kobayashiken/CytoGen/

Research field (2)： Molecular biology , Molecular biology

Research keywords (5)：分子遺伝学 , 分子老化学 , ゲノム生物学 , 分子生物学 , Molecular genetics

Research theme for competitive and other funds (20)：

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Papers (58)：

Takuro Shioi, Suguru Hatazawa, Eriko Oya, Noriko Hosoya, Wataru Kobayashi, Mitsuo Ogasawara, Takehiko Kobayashi, Yoshimasa Takizawa, Hitoshi Kurumizaka. Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature. 2024. 628. 8006. 212-220
Taichi Murai, Shuichi Yanagi, Yutaro Hori, Takehiko Kobayashi. Replication fork blocking deficiency leads to a reduction of rDNA copy number in budding yeast. iScience. 2024. 27. 3. 109120-109120
Junno Ohira, Mariko Sasaki, Takehiko Kobayashi. The peroxiredoxin Tsa1 extends the lifespan of budding yeast by maintaining the stability of the ribosomal RNA gene cluster. 2024
Hajime Futami, Mariko Sasaki, Takehiko Kobayashi. The histone chaperone CAF-1 maintains the stability of the ribosomal RNA gene cluster by suppressing end resection of replication-associated DNA double-strand breaks. 2024
Rei Yoshimoto, Yuta Nakayama, Ikuko Nomura, Ikuko Yamamoto, Yumeka Nakagawa, Shigeyuki Tanaka, Misuzu Kurihara, Yu Suzuki, Takehiko Kobayashi, Hiroko Kozuka-Hata, et al. 4.5SH RNA counteracts deleterious exonization of SINE B1 in mice. Molecular Cell. 2023. 83. 24. 4479-4493.e6

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MISC (77)：

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Patents (2)：

Books (44)：

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Lectures and oral presentations (60)：

DNA replication and noncoding transcription maintain the ribosomal RNA gene repeat
(2020)
哺乳動物細胞のリボソームRNA遺伝子に存在するreplication fork barrierの解析
(日本遺伝学会第85回大会 2013)
出芽酵母rDNAで生じたDSBは核膜孔周辺で修復される
(日本遺伝学会第85回大会 2013)
出芽酵母の鋳型DNA鎖修復機構
(日本遺伝学会第85回大会 2013)
Noncoding transcription regulates senescence in yeast
(Evolution of non-coding DNA 2013)

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Education (2)：

Professional career (1)：

Work history (7)：

- 現在東京大学定量生命科学研究所教授
2011 - 2016 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Department of Biological Sciences
The University of Tokyo Institute of Molecular and Cellular Biosciences
米国国立衛生研究所
ロシュ分子生物学研究所

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Committee career (11)：

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Awards (11)：

2023 - Genetic Society of Japan GGS Prize 2023 Changed life course upon defective replication of ribosomal RNA genes
2022/02 - 中央公論社新書大賞(第2位) 生物はなぜ死ぬのか
2022 - Genetic Society of Japan GGS Prize 2022
2020/09 - Genetic Society of Japan GGS Prize 2020
2018 - (公財)遠州頌徳会遺伝学大賞奨励賞

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Association Membership(s) (3)：

酵母遺伝学フォーラム , 日本遺伝学会 , 日本分子生物学会

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