Ninomiya Yuzo

ニノミヤユウゾウ | Ninomiya Yuzo

Affiliation and department：

Research field (1)： Oral medicine

Research theme for competitive and other funds (25)：

2018 - 2020 Molecular physiological basis of modulation and repair by oxidative stress in oral/gut/ brain chemosensory-endocrine interaction for dietary regulation.
2018 - 2019 Development of new technology for taste cell omics: exploring molecular logics of high calorie sensing and taste signal transduction
2015 - 2018 Research and development of measuring systems of breast cancer by mimicking olfactory systems of nematode C. elegans
2015 - 2017 Molecular basis of taste perception and humoral modulation of taste/hormone sensing cells in the oral-gut-brain circuit and its role in regulating food intake
2012 - 2015 Change of taste sensitivity due to daily intake of sweet solution

2014 - 2015 Molecular and neural mechanisms for detection, modulation and transmission of taste signal for fat preference

2011 - 2013 Molecular and Neural Mechanisms for Detection, Transmission and Modulation of taste signals derived from the oral cavity and gut

2006 - 2010 食の調節情報としての味覚の受容・認知機序の解明:味覚健康科学の創成

2006 - 2010 味覚センサーの空間的、時間的、種間的モーダルシフトによる細胞応答と個体応答の変化

2003 - 2003 味覚の制御機構に関する研究連携体制の構築と推進

2001 - 2003 The role of mastication in the mechanism of regulation of energy metabolism

2000 - 2002 Molecular mechanisms for expression of receptor and its related molecules in taste cells and selective synaptic formation between corresponding classes of taste cells and axons

2000 - 2000 「第2回IUPAC国際甘味物質討論会」の開催準備

1997 - 2000 Establishment of mouse strains with different allelic combinations of genes controlling taste receptor and transduction mechanisms.

1997 - 1999 Mechanism for specific synapse formation between taste cells and axons

1995 - 1996 Molecular genetic approach for identification of sweet taste receptors

1988 - 1990 Molecular Genetic Approaches for Taste Receptor Mechanisms

1988 - 1990 Molecular Tranduction Mechanism in Chemoreception

1987 - 1987 マウス味覚受容器の遺伝とその受容器としてのエンドルフィン代謝酵素の可能性

霊長類の味覚神経情報処理

グルマリン感受型味覚レセプターの分子遣伝学的同定

味神経-味細胞間シナプス形成における選択性と味細胞味覚受容メカニズムの発現

Taste neural coding system in primates

Molecular genetic identification of gurmarin-sensitive taste receptors

Induction of taste receptors through selective synaptic formation between taste nerve tibers and cells

Show all

Papers (188)：

Shusuke Iwata, Ryusuke Yoshida, Shingo Takai, Keisuke Sanematsu, Noriatsu Shigemura, Yuzo Ninomiya. Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway. Nutrients. 2023. 15. 13. 2941-2941
岩田周介, 吉田竜介, 高井信吾, 實松敬介, 重村憲徳, 二ノ宮裕三. カプサイシンのマウス味覚神経応答に対する影響(Capsaicin enhances responses of the gustatory nerve to sugars and salt in mice). Journal of Oral Biosciences Supplement. 2022. 2022. 382-382
Toshiaki Yasuo, G Craig Wood, Xin Chu, Peter Benotti, Christopher D Still, David D K Rolston, Robert F Margolskee, Yuzo Ninomiya, Peihua Jiang. Expression of taste signaling elements in jejunal tissue in subjects with obesity. Journal of oral biosciences. 2021
岩田周介, 吉田竜介, 高井信吾, 實松敬介, 重村憲徳, 二ノ宮裕三. アドレノメデュリンによるマウス鼓索神経甘味応答増強機構の解明(Adrenomedullin increases mouse chorda tympani nerve responses to sugars via T1R-independent mechanisms). Journal of Oral Biosciences Supplement. 2021. 2021. 275-275
Ryusuke Yoshida, Keiko Yasumatsu, Yuzo Ninomiya. The sweet taste receptor, glucose transporters, and the ATP-sensitive K+ (KATP) channel: sugar sensing for the regulation of energy homeostasis. Current Opinion in Physiology. 2021. 20. 57-63

ｍore...

MISC (303)：

岩田周介, 吉田竜介, 高橋慎平, 安尾敏明, 諏訪部武, 硲哲崇, 二ノ宮裕三, 二ノ宮裕三. カプサイシンはマウス味覚神経応答を糖特異的に増強する. Journal of Oral Biosciences Supplement (Web). 2023. 2023
岩田周介, 岩田周介, 吉田竜介, 高井信吾, 實松敬介, 實松敬介, 實松敬介, 重村憲徳, 重村憲徳, 二ノ宮裕三, et al. Capsaicin enhances responses of the gustatory nerve to sugars and salt in mice. Journal of Oral Biosciences Supplement (Web). 2022. 2022
岩田周介, 岩田周介, 吉田竜介, 高井信吾, 實松敬介, 實松敬介, 重村憲徳, 重村憲徳, 二ノ宮裕三. Adrenomedullin increases mouse chorda tympani nerve responses to sugars via T1R-independent mechanisms. Journal of Oral Biosciences Supplement (Web). 2021. 2021
岩田周介, 岩田周介, 井上真由子, 吉田竜介, 重村憲徳, 二ノ宮裕三, 二ノ宮裕三. Enhancement of sweet taste responses by Adrenomedullin may be mediated by T1Rs-independent sweet taste pathway in mice. Journal of Oral Biosciences Supplement (Web). 2020. 2020
安尾敏明, 安尾敏明, 硲哲崇, 二ノ宮裕三, 二ノ宮裕三. mRNA expression levels of taste-signaling molecules in jejunum of severe obese patients. Journal of Oral Biosciences Supplement (Web). 2020. 2020

ｍore...

Books (14)：

基礎歯科生理学第6版
医歯薬出版 2014
アミノ酸の科学と最新応用技術
2008
口腔内科学
飛鳥出版室 2008
基礎歯科生理学第5版
医歯薬出版 2008
Modification of responsiveness of taste receptor cells to sweeteners by the action of the mouse diabetic dbgene(共著)
Progress in Obesity Research : 8 1999

ｍore...

Lectures and oral presentations (306)：

Molecular mechanism for the suppressing effect of low pH on the sweet receptor sensitivity
(第97回日本生理学会大会 2020)
Leptin signaling pathway linking from activation of leptin receptor to KATP channel activation in sweet sensitive taste cells in mice.
(17th ISMNTOP 2018)
The potential effects of insulin signaling on mouse taste bud organoid.
(17th ISMNTOP 2018)
未知の味・カロリーシグナル伝達経路の探索と食調節
(千里ライフサイエンスセミナーN4(感覚のサイエンス~豊かな社会の実現に向けて~) 2019)
アドレノメデュリンによる T1Rs 非依存性経路を介するマウス鼓索神経糖応答への影響
(第61回歯科基礎医学会学術大会 2019)

ｍore...

Professional career (2)：

(BLANK)
(BLANK)

Committee career (9)：

2010/04 - 2014/03 九州大学教務委員会委員
2006/04 - 2010/03 九州大学学生委員会
2006/04 - 2009/03 日本うま味研究会会長
2006/04 - 日本味と匂学会会長
2003/04 - 日本味と匂学会運営委員

Show all

Awards (4)：

2012/04 - AChemS IFF Award
1998 - キリン賞
1998 - 高木賞
1987 - 中西研究奨励賞

Association Membership(s) (9)：

AChemS , ECRO , 日本咀嚼学会 , 日本神経科学会 , 日本生物物理学会 , 日本味と匂学会 , 日本分子生物学会 , 歯科基礎医学会 , 日本生理学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page