Rchr
J-GLOBAL ID:200901045561305856
Update date: Sep. 20, 2024
Iwata Hisato
イワタ ヒサト | Iwata Hisato
Affiliation and department:
Job title:
Professor,Faculty of Agriculture, Professor
Other affiliations (1):
Homepage URL (2):
http://ecotoxiwata.jp/
,
http://ecotoxiwata.jp/en/
Research field (7):
Landscape science
, Environmental agriculture
, Biological resource conservation
, Environmental effects of chemicals
, Environmental effects of radiation
, Environmental policy and society
, Environmental impact assessment
Research keywords (19):
bioinformatics
, interspecies difference
, sensitivity
, intracellular receptor
, omics
, 水圏環境保全学
, エコトキシコゲノミクス
, 生物遺伝子資源保全
, 環境化学
, 環境毒性学
, リスク評価
, 環境汚染
, 環境分析
, 生態系影響評価
, Ecotoxicogenomics and Proteomics
, Conservation of Genomic Resources
, Envirommental Toxicology
, Environmental Analysis and Environmental Contamination
, Environmental Risk Assessment
Research theme for competitive and other funds (45):
- 2024 - 2029 水棲哺乳類を対象とした化学物質の先進的な有害性・リスク評価法の開発
- 2024 - 2028 Search for novel, unregulated PPCPs with fish developmental and CNS toxicity
- 2023 - 2027 Spatiotemporal trend analysis and ecological risk assessment of monitoring and emerging environmental chemicals in the Asia-Pacific region
- 2022 - 2025 Establishment of cetacean iPS cells and application to neurotoxicity assays of environmental pollutants
- 2021 - 2025 メキシコ産ワニを対象とした次世代型モニタリング基盤の開発
- 2020 - 2024 Development of risk assessment method and present of brain transfer by ionic environmental contaminants using fish as an indicator
- 2019 - 2024 化学物質による水棲哺乳類細胞内受容体シグナル撹乱と感受性を規定する分子機構の解明
- 2019 - 2022 Biomagnification mechanism, spatiotemporal trend, and risk assessment of legacy and new environmental pollutants in various aquatic animal species
- 2019 - 2021 Development of a novel method for evaluating avian embryonic toxicity by continuous observation using a shell-less incubation system
- 2017 - 2019 Effects of environmental pollution and stress on gene expression profiles in Baltic salmons
- 2016 - 2019 Elucidation of widespread contamination status and bioaccumulation features of emerging persistent organic pollutants and assessment of their ecological effects
- 2014 - 2019 Multiple Omics Analysis to Understand the Species Differences in Chemical-intracellular Receptor Signaling Disruption
- 2015 - 2018 Establishment for long-term risk assessment system of oil spill and severe PAH pollution caused by large-scale disasters
- 2013 - 2016 Chemical hazard assessment with the genome-nuclear receptor interaction array system
- 2013 - 2016 Contamination status of organohalogen compounds and their metabolites of pet animals and effects on thyroid hormones homeostasis
- 2009 - 2014 Clarification of factors governing sensitivity of disruption of intracellular receptor-xenobiotic metabolizing enzyme signaling pathways by chemical substances
- 2008 - 2012 Environmental Contamination and Ecological Risk of Novel POPs in the Asian Developing Region
- 2009 - 2011 Large-scale differential display system with vertebrate-common degenerate oligonucleotide primers
- 2006 - 2008 Specific accumulation, metabolism and potential effects of persistent organohalogen compounds in predatory wild animals
- 2006 - 2008 野生鳥類のメタロチオネインを利用した重金属汚染のリスク評価に関する研究
- 2005 - 2008 High-throughput risk assay of chemicals using a nuclear receptor, CAR from aquatic animals
- 2006 - 2007 Risk assessment of chemicals using avian AHR isoforms
- 2004 - 2007 Studies on the Contamination Status, Bioaccumulation and Risk Assessment of PBDE, Brominated Flame Retardant, in the Environment
- 2005 - 2006 野生カワウ個体群のエコトキシコゲノミクス
- 2003 - 2006 メコンデルタにおける水資源の汚染実態と高次生物ならびにヒトに対する毒性影響に関する研究
- 2003 - 2006 Chemical Contamination in Mekong Delta and Their Toxic Effects on Higher Trophic Animals and Human
- 2002 - 2006 野生生物のエコトキシコゲノミクス・プロテオミクス
- 2002 - 2006 化学物質汚染による生態系への影響
- 2002 - 2006 Ecotoxicogenomics and proteomics in wildlife
- 2002 - 2006 Toxic impacts of environmental contaminants in ecosystem
- 2001 - 2004 毒性影響の種特異的感受性を決定する生体分子機構の解明
- 2001 - 2004 Understanding of molecular mechanisms responsible for species-specific sensitivity of chemical toxicity
- 2001 - 2004 Development of method for assessing species-specific risk of Ah receptor-mediated dioxin toxicity
- 2001 - 2003 野生生物における内分泌攪乱物質の汚染とそのリスク評価
- 2000 - 2003 Studies on the Environmental Chemistry for the Contamination and Toxic Effects of Bioaccumulative Endocrine Disrupters in Higher Wildlife
- 1997 - 2000 Development of assessment method for complex aquatic pollution using xenobiotic metabolic enzyme in liver of aquatic mammals
- 2000 - 化学物質のリスクを評価するためのバイオアッセイ法の開発
- 1997 - 1999 水棲哺乳動物における複合汚染状況を考慮した生体毒性学的研究 -環境汚染物質の生体内相互作用-
- 1997 - 1999 MUSSEL WATCH : MARINE POLLUTION MONITORING IN ASIAN WATERS
- 1997 - 1998 癌予防を目指す関連チトクロムP450の検出フォトダイナミック診断法の基礎研究
- 1996 - 1998 DEVELOPMENT OF CYTOCHROME P-450 PROCESS FOR THE STUDY OF TOXICOLOGY WITHOUT USING ANIMALS
- 1997 - 1997 環境中ダイオキシンによる免疫抑制機構の解明
- 1995 - 1997 Establishment of model animals for polymorphic drug metabolism associated with CYP2D
- 難分解性有機塩素化合物の地球規模での分布・動態・ゆくえ
- Global distribution,dynamics and fate of persistent organochlorines
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Papers (230):
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Hao Chen, Kaori Chigusa, Kazuki Kanda, Rumi Tanoue, Mari Ochiai, Hisato Iwata. Developmental toxicity of short-chain chlorinated paraffins on early-stage chicken embryos in a shell-less (ex-ovo) incubation system. Ecotoxicology and Environmental Safety. 2024. 276. 116304-116304
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Kazuki Kanda, Hisato Iwata. Tris(2-chloroethyl) phosphate (TCEP) exposure inhibits the epithelial-mesenchymal transition (EMT), mesoderm differentiation, and cardiovascular development in early chicken embryos. Science of The Total Environment. 2024. 922. 171242-171242
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Hoa Thanh Nguyen, Yuka Yoshinouchi, Masashi Hirano, Kei Nomiyama, Haruhiko Nakata, Eun-Young Kim, Hisato Iwata. In silico simulations and molecular descriptors to predict in vitro transactivation potencies of Baikal seal estrogen receptors by environmental contaminants. Ecotoxicology and Environmental Safety. 2023. 265. 115495-115495
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Kaori Chigusa, Kazuki Kanda, Hisato Iwata. Developmental toxicity in early chicken embryos on exposure to an organophosphorus flame retardant, tris(2-chloroisopropyl) phosphate. Ecotoxicology and environmental safety. 2023. 264. 115445-115445
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Akira Kubota, Masashi Hirano, Yuka Yoshinouchi, Xing Chen, Michiko Nakamura, Yumi Wakayama, Jae Seung Lee, Haruhiko Nakata, Hisato Iwata, Yusuke K. Kawai. In vivo and in silico assessments of estrogenic potencies of bisphenol A and its analogs in zebrafish (Danio rerio): Validity of in silico approaches to predict in vivo effects. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2023. 269. 109619-109619
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MISC (216):
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落合真理, 栗原望, 国末達也, 岩田久人. Neurotoxicity assessment of environmental pollutants using induced neurons of a finless porpoise. 環境化学討論会要旨集(CD-ROM). 2023. 31st
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落合真理, 栗原望, NGUYEN Hoa Thanh, 平野将司, 中田章史, 田島木綿子, 山田格, 岩田久人. Development of in vitro approaches for chemical hazard and risk assessment in cetaceans. 環境化学討論会要旨集(CD-ROM). 2023. 31st
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平川周作, 堀就英, 香月進, 宮脇崇, 平野将司, 岩田久人, 辻学. Characteristics of dioxins accumulated in Yusho patients and estimation of cytochrome P450-dependent metabolism by in silico docking simulation. 環境化学討論会要旨集(CD-ROM). 2022. 30th
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平川周作, 宮脇崇, 堀就英, 香月進, 平野将司, 岩田久人, 辻学. Analysis of factors affecting the characteristic accumulation patterns of PCB congeners in Yusho patients. 環境化学討論会要旨集(CD-ROM). 2021. 29th
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水川葉月, NGYUEN Hoa Thanh, 岩田久人, 野見山桂, 池中良徳, 中山翔太, 横山望, 市居修, 滝口満喜, KHIDKHAN Kraisiri, et al. PCBs曝露によるネコ肝トランスクリプトームへの影響. 環境化学討論会要旨集(CD-ROM). 2019. 28th. ROMBUNNO.1C-08
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Books (37):
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「環境ホルモンによる海洋汚染とクジラ・アザラシ・ホッキョクグマへの影響」海とヒトの関係学4 疫病と海(秋道智彌・角南篤 編)
西日本出版社 2021 ISBN:9784908443596
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生物の科学 遺伝~死体に学ぶクジラ・イルカの秘密~
株式会社エヌ・ティー・エス 2019
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環境毒性学: 環境毒性学の未来
朝倉書店 2011
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環境毒性学: バイオマーカー
朝倉書店 2011
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Arsenic in Geosphere and Human Diseases : Methylation of inorganic arsenic and genetic polymorphisms in arsenic (+III oxidation state) methyltransferase in a Vietnamese population
CRC Press 2010
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Lectures and oral presentations (276):
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Effects on the cardiovascular system of ex ovo chicken embryos exposed to tris (2-chloroethyl) phosphate (TCEP)
(International Symposium on Research Collaboration: Usable Science Resulting in Impact 2021)
-
In vitro and in silico assessment of the activation of chicken estrogen receptor α by bisphenol analogs
(2021)
-
Effects of organohalogen compounds and temperature on the liver transcriptome and proteome of Baltic salmon
(4th International Chemical Hazard Symposium 2021)
-
Multi omics analyses revealed varying susceptibilities of rat offspring to prenatal bisphenol A exposure
(4th International Chemical Hazard Symposium 2021)
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ex-ovo ニワトリ胚におけるリン酸トリス(2-クロロエチル)(TCEP)の心血管毒性作用機序の解明
(第44 回鳥類内分泌研究会 2020)
more...
Professional career (1):
Work history (7):
Awards (15):
- 2011/07 - 日本生態学会 第16回生態学琵琶湖賞
- 2011 - Biwako Prize For Ecology
- 2009 - 15th Pollutants Response in Marine Organisms (PRIMO15) Best Presentation Award
- 2006 - International Symposium 2006; Pioneering Studies of Young Scientists on Chemical Pollution and Environmental Changes Best Presentation Award
- 2006 - International Symposium 2006; Pioneering Studies of Young Scientists on Chemical Pollution and Environmental Changes Best Presentation Award
- 2005 - 日本環境毒性学会奨励賞
- 2005 - 13th Pollutants Response in Marine Organisms (PRIMO13) Best Presentation Award
- 2005 - 13th Pollutants Response in Marine Organisms (PRIMO13) Best Presentation Award
- 2004 - 日本環境毒性学会奨励賞
- 2004 - 7th International Symposium on Cytochrome P-450 Biodiversity and Biotechnology 優秀ポスター賞
- 2004 - 1st International Symposium on Environmental Behavior and Ecological Impacts of Persistent Toxic Substances ベストポスター賞
- 2004 - 7th International Symposium on Cytochrome P-450 Biodiversity and Biotechnology 優秀ポスター賞
- 2004 - 1st International Symposium on Environmental Behavior and Ecological Impacts of Persistent Toxic Substances ベストポスター賞
- 1994 - 環境汚染と毒性学の分野における優秀論文賞(SCIPRESS) (Quintessence, Excellence in Environmental Contamination and Toxicology (SCIPRESS))
- 1994 - QUINTESSENCE, Excellence in Environmental Contamination and Toxicology, SCIPRESS
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Association Membership(s) (10):
Society of Toxicology
, 日本分子生物学会
, 日本生化学会
, 日本BICER協議会
, 日本環境毒性学会
, 日本内分泌攪乱化学物質学会
, 日本獣医学会
, 環境科学会
, 日本環境化学会
, Society of Environmental Toxicology and Chemistry
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