Rchr
J-GLOBAL ID:200901045896159714
Update date: Oct. 21, 2024
Hashimoto Mamoru
ハシモト マモル | Hashimoto Mamoru
Affiliation and department:
Job title:
Professor
Homepage URL (1):
https://www.ist.hokudai.ac.jp/labo/bmsys/index.html
Research field (4):
Optical engineering and photonics
, Basic physical chemistry
, Biomaterials
, Biomedical engineering
Research keywords (5):
非線形光学
, 分光学
, 応用光学
, Spectroscopy
, Applied Optics
Research theme for competitive and other funds (42):
- 2023 - 2026 Advanced non-invasive optical measurement techniques for the constant monitoring of blood lipid components
- 2022 - 2025 Near-infrared light delivery in deep tissue using vivo helical optical waveguide formed by a topological ultrasound beam
- 2021 - 2024 Development of coherent Raman scattering microendoscope and application to unstained in-situ diagnosis
- 2020 - 2023 Development of transcutaneous optical measurement of blood particulate concentration for non-invasive monitoring of blood components
- 2020 - 2021 非線形ラマン散乱内視鏡実現のための4光波混合現象の削減法の開発
- 2017 - 2020 Artificial intelligence pathological diagnosis by hyperspectral nonlinear Raman scattering imaging
- 2015 - 2019 Non-invasion observation of the cell culture process by nonlinear optical microscopy
- 2017 - 2019 Super-resolution Imaging of nonlinear Raman atomic force imaging
- 2016 - 2019 Elucidation of the glycated collagen reaction in dentin and its application to next dental treatment
- 2016 - 2018 Development of fluorescence lifetime measurement for glycation screening for diabetes in vivo
- 2014 - 2017 Frequency-swept discrete Fourier transform spectroscopy ~demonstration and application in THz and near-infrared region~
- 2010 - 2017 高速誘導ラマン散乱スペクトルイメージングシステムの開発
- 2013 - 2016 Crystallization monitoring using higher order nonlinear Raman scattering microscopy
- 2011 - 2014 Multimodal molecular imaging system and its application for investigation of in vivo cell/tissue
- 2011 - 2013 カソードルミネッセンス顕微鏡による細胞中の高空間分解能蛋白質イメージング
- 2010 - 2012 Realtime CARS imaging of cellular response by stimulation of laser ablation
- 2008 - 2010 Development and application of real-time molecular microscope based on non-linear optical effect for biological specimen
- 2007 - 2009 Nonlinear Raman microscopy to detect membrane protein
- 2006 - 2008 サブミクロンの分解能で液晶分子の 3 次元配向を観測する顕微鏡
- 2007 - 2008 Nano-spectroscopy of molecular -metal complex
- 2006 - 2007 リアルタイム CARS 顕微鏡
- 2006 - 2007 テラヘルツ光照射に対する細胞応答のマルチフォトニクス・モニタリング
- 2006 - 2007 擬似ランダム符号を用いたパルスシェーピング多焦点CARS顕微鏡
- 2005 - 2007 Development of staining-free molecular imaging microscope for biological molecules and its application for quality control of cultured cells
- 2005 - 2006 分子のベクトル分布観測顕微鏡の開発
- 2005 - 2006 2 光子検出器を用いた二台のピコ秒モードロックレーザーの高精度同期
- 2006 - 2006 ピコ秒レーザーの自動安定発振・パルス長最適化機構の開発
- 2003 - 2005 非線形光学効果による赤外発生とプローブレス近接場赤外顕微鏡への展開”
- 2004 - 2005 Van der Waals'force-controlled nano Raman scattering spectroscopy
- 2004 - 2005 3次元偏光制御顕微鏡による3次元分子配向の3次元観測
- 2003 - 2004 Development of molecular imaging microscope for biological specimen and its application for tissue examination
- 2003 - 2004 非線形光学効果による赤外発生とプローブレス近接場赤外顕微鏡への展開
- 2001 - 2003 紫外励起 CARS 顕微鏡のシステムの開発と生物組織観察への応用
- 2001 - 2003 多焦点 CARS 顕微鏡による 3 次元分子分布イメージング
- 2001 - 2002 Development and application of a novel capillary chromatography system utilizing vital reaction of a single cell
- 2000 - 2001 コヒーレントアンチストークスラマン散乱による生体組織の3次元局所空間分子分光分析
- 1999 - 2001 コヒーレントアンチストークスラマン散乱顕微鏡の開発と生体計測への応用
- 2000 - 2001 Development of photometric detection system for tissue aging and study the localization of the aging in tissue
- 1999 - 2000 コヒーレントアンチストークスラマン散乱顕微鏡による生体試料の3次元イメージング
- 1999 - 2000 細胞の持つ優れた分子選択能力を活用したバイオセンサー型クロマトグラフィの開発
- 1999 - 2000 Detection of tissue aging by nanosecond self-fluorescence caused by AGE (Advanced Glycosylation Endproduct)
- 1998 - 1999 Visualization and quantification of intracellular magnesium ion to determine the influence of magnesium to pragnancy circulation
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Papers (119):
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Shukri Bin Korakkottil Kunhi Mohd, De Xing Lioe, Keita Yasutomi, Keiichiro Kagawa, Mamoru Hashimoto, Shoji Kawahito. A CMOS Double-Demodulation Lock-In Amplifier for Stimulated Raman Scattering Signal Detection. Electronics. 2022. 12. 1. 4-4
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Naoki Yamato, Hirohiko Niioka, Jun Miyake, Mamoru Hashimoto. Near real-time nerve visualization using coherent Raman scattering rigid endoscope and deep learning-based image processing for nerve-sparing surgery. Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry. 2022
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Naoki Yamato, Hirohiko Niioka, Jun Miyake, Mamoru Hashimoto. Author Correction: Improvement of nerve imaging speed with coherent anti-Stokes Raman scattering rigid endoscope using deep-learning noise reduction (Scientific Reports, (2020), 10, 1, (15212), 10.1038/s41598-020-72241-x). Scientific Reports. 2021. 11. 1
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Shun Kizawa, Mamoru Hashimoto. Ultrahigh-speed multiplex coherent anti-Stokes Raman scattering microspectroscopy using scanning elliptical focal spot. The Journal of Chemical Physics. 2021. 155. 14. 144201-144201
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Hiroki Ogawa, Mamoru Hashimoto. Avoidance of four-wave mixing in optical fiber bundle for coherent anti-Stokes Raman scattering endomicroscopy. Optics Letters. 2021. 46. 14. 3356-3356
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MISC (13):
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Shoichiro Fukushima, Hirohiko Niioka, Masayoshi Ichimiya, Masayoshi Ichimiya, Jun Miyake, Masaaki Ashida, Tsutomu Araki, Mamoru Hashimoto. Tens nanometer scale cathodoluminescence bioimaging with rare-earth doped nanophosphors. JSAP-OSA Joint Symposia, JSAP 2014. 2014
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Chikako Ninagawa, Hirohiko Niioka, Tsutomu Araki, Mamoru Hashimoto. Observation of anhydrated and hydrated DAST crystals using multiplex fourth order Raman microscope. JSAP-OSA Joint Symposia, JSAP 2014. 2014
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Niioka Hirohiko, Fukushima Syoichiro, Hashimoto Mamoru, Araki Tsutomu, Onoshima Daisuke, Yukawa Hiroshi, Baba Yoshinobu, Miyake Jun. 3P-247 Development of near infrared phosphor probes for deep tissue imaging toward the application for regenerative medicine. 2014. 66. 256-256
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Doan T. Kim Dung, Shoichiro Fukushima, Hirohiko Niioka, Masayoshi Ichimiya, Masayoshi Ichimiya, Masaaki Ashida, Tsutomu Araki, Mamoru Hashimoto, Jun Miyake. Multimodal bioimaging probes based on lanthanide doped Gd2O3 nanophosphors. JSAP-OSA Joint Symposia, JSAP 2014. 2014
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福島 昌一郎, 橋本 守. 生体相関イメージングを目指したCUPLナノ蛍光体の合成. ホソカワ粉体工学振興財団年報. 2014. 22. 117-120
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Patents (7):
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Polarization control device and polarization control method
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変調光検出のSN比を向上する方法
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スペクトル分解能とスペクトル確度を向上するフーリエ変換型分光法、分光装置および分光計測プログラム
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カソードルミネッセンス用標識試薬
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波長走査パルス光同期システムおよびその制御方法
more...
Books (5):
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CARS Microscopy: Implementation of nonlinear vibrational spectroscopy for far-field and near-field imaging
2012
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顕微分光法 ナノ・マイクロの世界を見る分光法
講談社サイエンティフィク 2009
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バイオイメージングがわかる
2005
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Biological Imaging and Sensing
Springer 2004
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Handbook of Vibrational Spectroscopy
John Wiley & Sons, Ltd 2001
Lectures and oral presentations (143):
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CMOSイメージセンサーを用いたマルチプレックス誘導ラマン散乱分光法”, "新しいイメージングを実現する最先端CMOSイメージセンサ
(Optics & Photonics Japan 2023 2023)
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Development of Lissajous scanning fluorescence endomicroscope using polarization-maintaining fiber
(OSJ-JSAP Joint Symposia on Optics, Optics & Photonics Japan 2023 2023)
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Imaging of trans lipid-mobilization by coherent Raman microspectroscopy
(OSJ-JSAP Joint Symposia on Optics, Optics & Photonics Japan 2023 2023)
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Label-free imaging by coherent Raman scattering endoscopy
(2023 International Workshop on the New Frontiers in Convergence Science and Technology of Hokkaido University - Seoul National Universty 26th Joint Symposium 2023)
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第二高調波発生関節鏡の開発とビーム走査手法の検討
(第21回医用分光学研究会 2023)
more...
Education (3):
- 1997 - The University of Tokyo
- 1989 - 1991 Osaka University Graduate School of Engineering Division of Applied Physics
- 1985 - 1989 Osaka University School of Engineering
Professional career (1):
Work history (9):
- 2019/04 - 現在 Hokkaido University Division of Bioengineering and Bioinformatics, Faculty of Information Science and Engineering professor
- 2016/10 - 2019/03 Hokkaido University Graduate School of Information Science and Technology Division of Bioengineering and Bioinformatics Professor
- 2007/04 - 2016/09 Osaka University Graduate School of Engineering Science Department of Mechanical Science and Bioengineering Division of Bioengineering Assoc. Professor
- 2003/04 - 2007/03 Osaka University Graduate School of Engineering Science Department of Mechanical Science and Bioengineering Division of Bioengineering
- 2002/11 - 2003/03 Osaka University Graduate School of Engineering Science Assoc. Professor
- 1999/04 - 2002/10 Osaka University Graduate School of Engineering Science Department of Systems Innovation Division of Mathematical Science
- 1997/08 - 1999/03 Osaka University Graduate School of Engineering Science
- 1996/04 - 1997/07 The University of Tokushima Faculty of Engineering
- 1991/04 - 1996/03 神奈川科学技術アカデミー 濵口「極限分子計測」プロジェクト 研究員
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Committee career (6):
Awards (6):
Association Membership(s) (5):
レーザ顕微鏡研究会
, 日本光学会
, 日本分光学会
, 日本応用物理学会
, 日本機械学会
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