Rchr
J-GLOBAL ID:200901046238347147   Update date: Nov. 21, 2024

Takai Shinji

タカイ シンジ | Takai Shinji
Affiliation and department:
Job title: Professor
Other affiliations (1):
  • Osaka Medical and Pharmaceutical University  Department of Pharmacology   Professor
Homepage URL  (1): https://www.ompu.ac.jp/u-deps/grd/
Research field  (1): Pharmacology
Research keywords  (2): 薬理学一般 ,  Pharmacology in General
Research theme for competitive and other funds  (48):
  • 2024 - 2027 Clarification of therapeutic strategies and mast cells on salivary gland adenoid cystic carcinoma and oral cancer
  • 2023 - 2027 Development of extracorporeal VAD housing having excellent blood compatibility using anti-fouling peptide immobilization technology
  • 2022 - 2026 Verification of stenosis-preventive effect of bifunctionalized artificial blood vessels utilizing peptide modification technology
  • 2022 - 2025 Possibility of neuroprotection by inhibition of tau phosphorylation - Investigation in optic nerve injury
  • 2022 - 2025 Pathophysiological role of chymase in diabetic complications
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Papers (291):
  • Shintaro Shigesato, Denan Jin, Wataru Osumi, Kohei Taniguchi, Koji Komeda, Mitsuhiro Asakuma, Hideki Tomiyama, Shinji Takai, Sang-Woong Lee. Mechanisms of polyglycolic acid sheet-induced abdominal wall adhesions in hamsters. Surgery today. 2024
  • Hiroe Toba, Shinji Takai. Exploring the roles of SPARC as a proinflammatory factor and its potential as a novel therapeutic target against cardiovascular disease. American Journal of Physiology-Heart and Circulatory Physiology. 2024. 327. 5. H1174-H1186
  • Hirofumi Morihara, Shunichi Yokoe, Shigeo Wakabayashi, Shinji Takai. TMEM182 inhibits myocardial differentiation of human iPS cells by maintaining the activated state of Wnt/β-catenin signaling through an increase in ILK expression. FASEB BioAdvances. 2024. 6. 11. 565-579
  • Masanari Yoshimoto, Denan Jin, Hiroshi Sakonjo, Shinji Takai. Renoprotective Effects of Chymase Inhibition on Cisplatin-Induced Nephrotoxicity in Mice. Bulletin of Osaka Medical and Pharmaceutical University. 2024. 70. 1. 25-34
  • Tsunehiko Ikeda, Denan Jin, Shinji Takai, Kimitoshi Nakamura, Emika Nemoto, Shota Kojima, Hidehiro Oku. Blastocyst-like Structures in the Peripheral Retina of Young Adult Beagles. International Journal of Molecular Sciences. 2024. 25. 11. 6045-6045
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MISC (280):
  • 渡瀬謙仁, 寺井健太郎, 金徳男, 金宮健翁, 中倉兵庫, 柴原伸久, 有馬秀二, 高井真司. ペリオスチンのAVGの狭窄への関与について. 奈良県医師会透析部会誌. 2023. 28. 1
  • 米山弘樹, 北村育子, 植村優希, 吉田彩葉, 豊田美唯, 細畑圭子, 金徳男, 葉山登, 宇佐美吉英, 高井真司. 腎疾患治療薬開発を指向した新規vanin-1阻害剤の創製. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2023. 28th
  • 飯田達也, 細畑圭子, 東悠輔, 林真白, 米山弘樹, 金徳男, 北村育子, 植村優希, 吉田彩葉, 豊田美唯, et al. 新規vanin-1阻害剤の急性腎障害軽減効果の検討. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2023. 28th
  • 寺井 健太郎, 金 徳男, 渡瀬 謙仁, 今川 彰久, 高井 真司. 糖尿病マウスにおけるキマーゼ阻害によるアルブミン尿の減少機序の解明. 糖尿病. 2021. 64. Suppl.1. I-5
  • Keiko Hosohata, Shinji Takai. 食塩感受性高血圧による尿細管障害と非侵襲性バイオマーカー. Precision Medicine. 2021. 4. 69-73
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Patents (15):
  • VANIN-1INHIBITOR
  • Vanin-1 inhibitor
  • Methods for measuring Vanin-1 protein in specimens by immunochromatography and its testing instruments
  • 人工血管、及び人工血管の製造方法
  • 癒着治療薬、癒着の治療方法、術後癒着マーカー、および術後癒着の罹患の可能性を試験する方法
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Books (15):
  • 生体吸収性外科材料の使い方と新しい材料の有用性
    技術情報協会 2024 ISBN:9784867980149
  • Hypertension
    2020
  • カラ-新しい薬理学(教科書)
    西村書店 2018
  • 生体吸収素材の開発と安全性評価
    技術情報協会 2017
  • 実はすごい!ACE阻害薬
    南江堂 2015
more...
Professional career (1):
  • Doctor (Osaka Medical College)
Work history (3):
  • 2023/07 - 現在 Osaka Medical and Pharmaceutical University Department of Pharmacology Professor
  • 2021/04 - 現在 Osaka Medical and Pharmaceutical University Graduate School of Medicine, Department of Innovative Medicine Professor
  • 2014/07 - 2021/03 Osaka Medical College Graduate School of Medicine, Department of Innovative Medicine Professor
Committee career (6):
  • 日本循環薬理学会 幹事
  • 日本病態プロテアーゼ学会 理事
  • 日本心脈管作動物質学会 評議員
  • 日本高血圧学会 評議員・顕彰委員会委員
  • 日本薬理学会 代議員・評議員・研究推進委員会委員・学術企画委員会委員
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Awards (7):
  • 2015 - 日本薬理学会JPS優秀論文賞
  • 2003 - 日本薬理学会学術奨励賞
  • 2003 - Young Investigator's Award fron Japanese Pharmacological Society
  • 2001 - 日本循環薬理学会 Young Investigator's Award
  • 2001 - 心血管病若手奨励賞
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Association Membership(s) (6):
日本病態プロテアーゼ学会 ,  Japanese Association of Cardiovascular Pharmacology ,  日本心脈管作動物質学会 ,  日本高血圧学会 ,  日本薬理学会 ,  American Heart Association
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