Rchr
J-GLOBAL ID：200901046473622082   Update date: Apr. 08, 2024

Handa Hiroshi

ハンダ ヒロシ | Handa Hiroshi
Affiliation and department：
Gunma University Hematology, Graduate School of Medicine

About Gunma University Hematology, Graduate School of Medicine


Job title： Lecturer
Research field  (1)： Other
Research keywords  (4)： 血液検査学 ,  血液腫瘍学 ,  Laboratory Hematology ,  Hematology Oncology
Research theme for competitive and other funds  (7)：
  • 2020 - 2023 急性NK白血病における腫瘍微小環境解析
  • 2014 - 2017 Analyzing role of non-coding RNA in multiple myeloma by using next generation sequnecer
  • 2012 - 2015 Role of AID and MMSET in progression of multiple myeloma
  • 2011 - 2013 Development of long-term culture system for human MDS specific iPS
  • 2010 - 2012 The expression of Toll-like receptor in myelodysplastic syndrome
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Papers (325)：
  • Yasuo Mori, Jun Takizawa, Yuna Katsuoka, Naoki Takezako, Koji Nagafuji, Hiroshi Handa, Junya Kuroda, Kazutaka Sunami, Tomohiko Kamimura, Ryosuke Ogawa, et al. Autologous HSCT with novel agent-based induction and consolidation followed by lenalidomide maintenance for untreated multiple myeloma. Cancer science. 2024
  • Yasunori Kogure, Hiroshi Handa, Yuta Ito, Masaki Ri, Yuichi Horigome, Masaki Iino, Yoriko Harazaki, Takahiro Kobayashi, Masahiro Abe, Tadao Ishida, et al. ctDNA improves prognostic prediction in relapsed/refractory MM receiving ixazomib, lenalidomide, and dexamethasone. Blood. 2024
  • Shin-Ichi Fuchida, Mizuki Ogura, Tadao Ishida, Hiroyuki Hata, Hiroshi Handa, Nagaaki Katoh, Chiaki Nakaseko, Kazutaka Sunami, Yuta Katayama, Hironobu Nobata, et al. A retrospective analysis of clinical features and treatment outcome in 21 patients with immunoglobulin M-related light-chain amyloidosis in Japan: a study from the Amyloidosis Research Committee. International journal of hematology. 2023. 118. 4. 443-449
  • Yuichi Horigome, Masaki Iino, Yoriko Harazaki, Takahiro Kobayashi, Hiroshi Handa, Yasushi Hiramatsu, Taiga Kuroi, Kazuki Tanimoto, Kosei Matsue, Masahiro Abe, et al. A prospective, multicenter, observational study of ixazomib plus lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma in Japan. Annals of hematology. 2023
  • 白石 菜月, 後藤 七海, 小田 司, 笠松 哲光, 青柳 瑠南, 大森 綺音, 柳澤 宏太, 糸井 悠晏, 飯田 南美, 根岸 光, et al. HIF-1αの安定化剤を用いた模擬低酸素環境下における多発性骨髄腫細胞の遺伝子発現解析. The Kitakanto Medical Journal. 2023. 73. 3. 254-254
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MISC (485)：
  • 早川輝, 早川輝, 佐野利恵, 高橋遥一郎, 大川貴史, 窪理英子, 原田恩, 福田治紀, 横濱章彦, 半田寛, et al. ABO式血液型抗原量低下を示した骨髄異形成症候群の機序の解析. 日本輸血細胞治療学会誌. 2022. 68. 2
  • 安井 寛, 小林 真之, 佐藤 広太, 近藤 幹也, 石田 禎夫, 海渡 裕太, 田村 秀人, 半田 寛, 築根 豊, 佐々木 純, et al. セル・フリーDNAによる多発性骨髄腫の早期再発診断(Circulating cell-free DNA in the peripheral blood plasma of patients is an informative biomarker for multiple myeloma relapse). International Journal of Myeloma. 2021. 11. 2. 91-91
  • 安井寛, 小林真之, 小林真之, 近藤幹也, 石田禎夫, 田村秀人, 半田寛, 佐々木純, 田中紀奈, 田中淳司, et al. Circulating cell-free DNA in the patient’s peripheral blood plasma is a sensitive biomarker for multiple myeloma relap. 日本癌学会学術総会抄録集(Web). 2020. 79th
  • Mitsuhito Hirano, Yoichi Imai, Takahiko Murayama, Kota Sato, Junichi Yamamoto, Takumi Ito, Muneyoshi Futami, Masaki Ri, Hiroshi Yasui, Noriko Gotoh, et al. Combined Inhibition of HDAC and AKT As a Strategy to Overcome Multi-Drug Resistance in Patients with Multiple Myeloma. BLOOD. 2019. 134
  • Rurika Okuda, Hideki Makishima, Yasuhito Nannya, Yotaro Ochi, Tetsuichi Yoshizato, Yasunobu Nagata, Kenichi Yoshida, Masashi Sanada, June Takeda, Ryunosuke Saiki, et al. Distinct, Ethnic, Clinical, and Genetic Characteristics of Myelodysplastic Syndromes with Der(1;7). BLOOD. 2019. 134. P-2376
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Books (5)：
  • これ血液悪性疾患?自分の守備範囲? 非専門医のための見分け方
    医学書院 2010
  • EBM血液疾患の治療2010-2011 形質細胞性白血病に対する治療は
    中外医学社 2010
  • 造血器腫瘍治療 これは困ったぞどうしよう 2版 原発性マクログロブリン血症患者の意識が朦朧としてきた。血清IgM値が11g/dlある。さてどうしよう?
    中外医学社 2010
  • 造血器腫瘍治療-これは困ったぞどうしよう!
    中外医学社 2009
  • 造血器腫瘍治療-これは困ったぞどうしよう!
    中外医学社 2006
Lectures and oral presentations  (66)：
  • Mircro-RNA expression is associated with expression of DNA methyltransferases and anti-apoptotic gene mcl-1 in multiple myeloma and monoclonal gammopathy with undetermined significance (MGUS)
    (European Hematology Association (EHA) 2012)
  • Association between micro-RNA and epigenetic modifiers DNA methyltransferases (DNMTs), histone deacetylases (HDACs) in multiple myeloma (MM) and monoclonal gammmopathy with undetermined significance (MGUS)
    (American Society of Hematology 2012)
  • Mircro-RNA expression is associated with expression of DNA methyltransferases and anti-apoptotic gene mcl-1 in multiple myeloma and monoclonal gammopathy with undetermined significance (MGUS)
    (European Hematology Association (EHA) 2012)
  • Association between micro-RNA and epigenetic modifiers DNA methyltransferases (DNMTs), histone deacetylases (HDACs) in multiple myeloma (MM) and monoclonal gammmopathy with undetermined significance (MGUS)
    (American Society of Hematology 2012)
  • Human telomerase reverse transcriptase (hTERT) expression detected by flow cytometry in CD34 positive progenitor fraction in myelodysplasitc syndorme and acute myeloid leukemia
    (15th Congress of the European Hematology Association 2010)
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Education (2)：
  • - 1990 Gunma University Faculty of Medicine School of Medicine
  • - 1990 Gunma University Faculty of Medicine
Professional career (1)：
  • PhD (Gunma University)
Work history (8)：
  • 2001 - 2002 Gunma University University Hospital, Hematology
  • 2001 - 2002 Gunma University Hospital, Division of Hematology
  • 2002 - - 群馬大学医学部保健学科応用検査学助手
  • 2002 - - Gunma University, Faculty of Medicine, School of Health Science
  • 1996 - 1998 Gunma University University Hospital
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