Rchr
J-GLOBAL ID:200901046496201580   Update date: Nov. 29, 2024

Osada Hiroyuki

Osada Hiroyuki | Osada Hiroyuki
Affiliation and department:
Job title: Specially Appointed Director
Other affiliations (3):
Homepage URL  (1): http://www.cbrg.riken.jp/csrs/ja/
Research field  (2): Applied biochemistry ,  Applied microbiology
Research keywords  (4): ケミカルバンク ,  天然物 ,  化合物バンク ,  ケミカルバイオロジー
Research theme for competitive and other funds  (31):
  • 2021 - 2024 人工知能を活用した抗真菌剤の開発研究
  • 2017 - 2022 プロテオミクスをベースにした化学シグナル解析技術開発
  • 2017 - 2022 Frontiers in Chemical Communications
  • 2018 - 2021 Chemical biology research solves the 3W1H of tenuazonic acid
  • 2016 - 2021 先端モデル動物支援プラットフォーム
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Papers (354):
  • Yusuke Toda, Hiroaki Fujita, Koshiki Mino, Takuto Koyama, Seiji Matsuoka, Toshie Kaizuka, Mari Agawa, Shigeyuki Matsumoto, Akiko Idei, Momoko Nishikori, et al. Synergistic involvement of the NZF domains of the LUBAC accessory subunits HOIL-1L and SHARPIN in the regulation of LUBAC function. Cell Death & Disease. 2024. 15. 11
  • Quy Van Vu, Nhat Thi Vu, Kosuke Baba, Saki Sasaki, Ryuichi Tamura, Kyoko Morimoto, Hiroyuki Hirano, Hiroyuki Osada, Takao Kataoka. Porphyrin derivatives inhibit tumor necrosis factor α-induced gene expression and reduce the expression and increase the cross-linked forms of cellular components of the nuclear factor κB signaling pathway. European Journal of Pharmacology. 2024. 977
  • Yuka Yokota, Keiko Takaki, Kosuke Baba, Saki Sasaki, Hiroyuki Hirano, Hiroyuki Osada, Takao Kataoka. Amiodarone inhibits the Toll-like receptor 3-mediated nuclear factor κB signaling pathway by blocking organelle acidification. Biochemical and biophysical research communications. 2024. 708. 149801-149801
  • Islam A. Abdelhakim, Yushi Futamura, Yukihiro Asami, Hideaki Hanaki, Naoko Kito, Sachiko Masuda, Arisa Shibata, Atsuya Muranaka, Hiroyuki Koshino, Ken Shirasu, et al. Expression of Syo_1.56 SARP Regulator Unveils Potent Elasnin Derivatives with Antibacterial Activity. Journal of Natural Products. 2024
  • Katsuyuki Sakai, Yushi Futamura, Toshihiko Nogawa, Yuzhu Zhao, Hiroyuki Koshino, Hiroyuki Osada, Shunji Takahashi. Production of Kinanthraquinone D with Antimalarial Activity by Heterologous Gene Expression and Biotransformation in Streptomyces lividans TK23. Journal of Natural Products. 2024. 87. 4. 855-860
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MISC (133):
  • LI Ziyu, 渡邉正悟, 岸本真治, 奥村英夫, 川谷誠, 長田裕之, 長田裕之, 渡辺賢二. Synthesis and evaluation of biological activities for novel dihydroorotate dehydrogenase inhibitors. 日本薬学会年会要旨集(Web). 2023. 143rd
  • Makoto Muroi, Hiroyuki Osada. Proteomics-based target identification of natural products affecting cancer metabolism. Journal of Antibiotics. 2021. 74. 10. 639-650
  • 野川俊彦, RAWA Mira Syahfriena Amir, RAWA Mira Syahfriena Amir, 岡野亜紀子, 二村友史, 中村健道, WAHAB Habibah A., 長田裕之. New Peptaibols Isolated from a Fungus Trichoderma sp. RK10-F026 as Culture Condition Depending Metabolites. 質量分析総合討論会講演要旨集. 2021. 69th
  • 本山高幸, 野川俊彦, 清水猛, 川谷誠, 二村友史, YUN Choong-Soo, 長田裕之. Isolation of new bioactive natural products by using homologs of a new type secondary metabolism enzyme TAS1. 日本農芸化学会大会講演要旨集(Web). 2020. 2020
  • 古山祐貴, 古山祐貴, 本山高幸, 野川俊彦, 鎌倉高志, 長田裕之. Functional analysis of secondary metabolites of the rice blast fungus induced by actinomycetal antibiotics. 日本農芸化学会大会講演要旨集(Web). 2020. 2020
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Books (1):
  • Bioprobes
    Springer Nature 2017
Education (1):
  • The University of Tokyo
Professional career (1):
  • 農学博士 (東京大学)
Work history (11):
  • 2024/04 - 現在 Institute of Microbial Chemistry (BIKAKEN) Specially Appointed Director
  • 2022/04 - 現在 University of Shizuoka School of Pharmaceutical Sciences Professor
  • 2021/04 - 現在 Waseda University Research Institute for Science and Engineering
  • 2013/04 - 現在 RIKEN Center for Sustainable Resource Science Unit Leader
  • (この間 平成15年 仏国 ルイパスツール大学客員教授)
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Committee career (5):
  • 2019/01 - 現在 日本癌学会 名誉会員
  • 2018/04 - 現在 日本抗生物質学術協議会 常務理事
  • 2015/06 - 2018/06 日本がん分子標的学会 理事長
  • 日本ケミカルバイオロジー学会 会長
  • 日本農芸化学会 フェロー
Awards (9):
  • 2021/04 - Medal with Purple Ribbon
  • 2016/03 - 日本農芸化学会 特別賞
  • 2015/04 - ドイツ Inhoffen Medal
  • 日本農芸化学賞
  • 日本バイオインダストリー協会賞
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Association Membership(s) (5):
日本農芸化学会 ,  日本生化学会 ,  日本抗生物質学術協議会 ,  日本がん分子標的学会 ,  日本癌学会
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