Rchr
J-GLOBAL ID：200901046551254532   Update date: Jan. 30, 2024

YASUSHI IZUMI

イズミ ヤスシ | YASUSHI IZUMI
Affiliation and department：
National Institutes of Natural Sciences National Institute for Physiological Sciences

About National Institutes of Natural Sciences National Institute for Physiological Sciences


Job title： Assistant Professor
Homepage URL  (1)： http://www.nips.ac.jp/dcs/
Research field  (2)： Cell biology ,  Molecular biology
Research keywords  (7)： epithelial cell ,  cell polarity ,  Drosophila ,  septate junction ,  cell-cell junction ,  gut ,  stem cell
Research theme for competitive and other funds  (8)：
  • 2022 - 2025 ショウジョウバエ上皮細胞間隙バリア機能低下による幹細胞増殖の促進機構の解明
  • 2019 - 2022 The role of epithelial barrier in Drosophila intestinal homeostasis
  • 2015 - 2018 Analysis of mechanism involved in cell-cell junction formation using Drosophila as a model system
  • 2014 - 2017 The molecular mechanism underlying the epithelial barrier formation by tricellular tight junctions
  • 2009 - 2010 Identification and characterization of novel proteins regulating epithelial barrier functions
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Papers (28)：
  • Sima Jonusaite, Nathalie Oulhen, Yasushi Izumi, Mikio Furuse, Takashi Yamamoto, Naoaki Sakamoto, Gary Wessel, Andreas Heyland. Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier. Developmental Biology. 2022
  • Maiko Abe, Takumi Kamiyama, Yasushi Izumi, Qingyin Qian, Yuma Yoshihashi, Yousuke Degawa, Kaori Watanabe, Yukako Hattori, Tadashi Uemura, Ryusuke Niwa. Shortened lifespan induced by a high-glucose diet is associated with intestinal immune dysfunction in Drosophila sechellia. Journal of Experimental Biology. 2022. 225. 21
  • Yasushi Izumi, Kyoko Furuse, Mikio Furuse. The novel membrane protein Hoka regulates septate junction organization and stem cell homeostasis in the Drosophila gut. Journal of Cell Science. 2021. 134. 6. jcs.257022-jcs.257022
  • Klaus W Beyenbach, Frederike Schöne, Leonhard F Breitsprecher, Felix Tiburcy, Mikio Furuse, Yasushi Izumi, Heiko Meyer, Sima Jonusaite, Aylin R Rodan, Achim Paululat. The septate junction protein Tetraspanin 2A is critical to the structure and function of Malpighian tubules in Drosophila melanogaster. American journal of physiology. Cell physiology. 2020. 318. 6. C1107-C1122
  • Sima Jonusaite, Klaus W Beyenbach, Heiko Meyer, Achim Paululat, Yasushi Izumi, Mikio Furuse, Aylin R Rodan. The septate junction protein Mesh is required for epithelial morphogenesis, ion transport, and paracellular permeability in the Drosophila Malpighian tubule. American journal of physiology. Cell physiology. 2020. 318. 3. C675-C694
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MISC (16)：
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Lectures and oral presentations  (6)：
  • The role of the epithelial barrier function in Drosophila gut homeostasis”
    (The 13th Japanese Drosophila Research Conference 2018)
  • Molecular dissection of septate junctions in the Drosophila midgut.
    (第70回 日本細胞生物学会、第51回 日本発生生物学会 合同大会 シンポジウム “Metazoan Cell-cell Junctions: Molecules, Structures, Mechanics and Evolution. 2018)
  • Identification and characterization of novel smooth septate junction proteins in Drosophila.
    (International tight junction conference. 2016)
  • ショウジョウバエ内胚葉上皮のセプテートジャンクションの形成機構
    (第68回細胞生物学会大会 シンポジウム「セルシャンクションを介する細胞と場の協調 」 2016)
  • 細胞の隙間を塞ぐしくみの進化と多様性
    (JT生命誌研究館20周年記念 BRHシンポジウムシリーズ 第3,4回合同「系統関係、形態、生態をむすぶ新ゲノム時代の進化学:細胞のつながり方の進化と表現型の進化」 2014)
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Professional career (2)：
  • 博士(医学)(横浜市立大学)
  • 修士(理学)(横浜市立大学)
Work history (7)：
  • 2015/04 - 現在 National Institutes of Natural Sciences
  • 2013/07 - 2015/03 Kobe University Graduate School of Medicine
  • 2008/01 - 2013/06 Kobe University Graduate School of Medicine
  • 2005/04 - 2007/12 理化学研究所発生再生科学総合研究センター 非対称細胞分裂研究グループ 基礎科学特別研究員
  • 2001/10 - 2005/03 理化学研究所発生再生科学総合研究センター 非対称細胞分裂研究グループ 研究員
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Association Membership(s) (3)：
Japanese Drosophila Reseach Conference ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR CELL BIOLOGY
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