Kawai Keiichi

2016 - 2020 PET Molecular Imaging for the molecular targeted cancer therapy focused on EGFR for personalized Medicine

2018 - 2020 個別化薬物療法最適化の基盤となる薬物代謝酵素活性を評価する核医学画像診断法の確立

2015 - 2018 Development of high accuracy multidrug resistance prediction method using SPECT imaging for individualized anticancer therapy

2014 - 2018 Nuclear medicine imaging toward therapeutic strategy of atherosclerosis: Experimental research to establish EBM

2015 - 2017 Study on prostaglandin transporter as a novel target for anti-inflammatory drugs

2015 - 2016 Development strategy of tumor diagnostic agent by system upregulated functional biomolecule based on expression analysis of tumor associated transporter.

2013 - 2016 Development of a molecular targeted radiolabeled diagnostic agent useful for personalized drug therapy of psychoneurotic diseases.

2012 - 2015 Quantitative measurement of a new small animal SPECT/CT scanner with a semiconductor detector

2011 - 2015 Development and Assessment of HDAC Targeted PET Imaging

2012 - 2014 The design strategy for tumor diagnostic agents utilizing the functional biomolecule expression system based on gene expression analysis of tumor cells.

2011 - 2013 The correlation between FDG uptake and various oncogenes expression in pancreas cancer

2011 - 2012 Early andspecific detection of unstable atherosclerotic pl:aqTuiesssue factor imaging using pre-targeting systems

2009 - 2011 The probe design strategy of post-FDG tumor diagnostic agents based on the functional biomolecule expression analysis of human cultured cells.

2008 - 2011 Development of novel radiopharmaceuticals for diagnosis of cerebral neurodegeneration and functional recoverry after intrastriatal grafts / gene thrapy.

2008 - 2010 Application of radiological dynamic imaging for rehabilitation medicine

2008 - 2010 Novel Tumor Seeking PET Imaging focused on Epigenetic Regulation by Histone Deacetylases

2007 - 2009 腫瘍血管新生の可視化を可能にする分子イメージング剤の開発

2007 - 2009 Targeted radionuclide therapy for malignant neuroendcrine tumors combined with antiangiogenic therapy : from bench to bedside

2009 - 薬物の組織移行性に影響する複数の血清蛋白結合状態の同時測定法

2007 - 2008 Analysis of first-pass effect in small intestinal mucosa and its application to prediction of drug absorption behavior after oral administration

2006 - 2008 Prediction of cancer therapeutic effect with molecular targeting agents by molecular imaging of the signal transduction

2005 - 2007 Development of isoform-specific amino acid transporter imaging agent

2005 - 2007 Development of novel radiopharmaceuticals for early stage diagnosis of cerebral neurodegeneration and functional recoverry after intrastriatal grafts.

2005 - 2007 The design of positron labeled artificial amino acids as post-FDG tumor diagnostic agents.

2005 - 2006 Analysis of physiological factors regulating oral absorption behaviors of drugs and its application to prediction of plasma concentration-time profile

2004 - 2006 Development of specific, universal targeted radiotherapy through induction of avidin on cancer cell membrane and internalization of scavenger receptor

2003 - 2005 transporter遺伝子導入による腫瘍の内照射療法および核医学画像診断の開発

2002 - 2004 Research on a new internal radiation therapy agent targeting for hypoxic tumors.

2002 - 2004 脳内神経変性疾患の早期検出を可能にする新規放射性診断薬の開発に関する研究

2001 - 2003 Development of isoform-selective amino acid transporter imaging agent

2000 - 2002 The change of cerebral blood flow in depression of hypothyroidism in induced by post-thyroidectomy

2000 - 2002 腫瘍特異的代謝亢進に基づく癌の内部照射治療を可能にするヨウ素標識試薬の開発

1999 - 2001 脳内神経伝達機能の画像診断を可能にする新規放射性診断薬の開発に関する研究

1998 - 1999 脳内ドーパミン神経機能診断を目的とする放射性診断薬の開発と診断法の確立

1997 - 1999 癌の免疫核医学診断・治療を目的とする腫瘍部位解裂性ヨウ素標識試薬の開発

1997 - 1998 脳内神経伝達機能の画像診断を目的とした新規放射性診断薬の開発に関する基礎研究

1997 - 1997 癌の免疫核医学治療を目的とする腫瘍部位解裂性ヨウ素標識試薬の開発

1996 - 脳内神経伝達機能の画像診断を目的とした放射性診断薬の開発に関する基礎研究

1995 - 脳内アミノ酸代謝機能の画像診断を目的とした放射性診断薬の開発に関する基礎研究

1994 - 脳内アミノ酸代謝機能の画像診断を目的とした放射性診断薬の開発に関する基礎研究

1990 - 精神疾患,痴呆などの画像診断を目的とした in vivo 脳代謝機能放射性診断薬の開発に関する研究

1990 - 心筋交感神経機能の画像診断を目的とした偽伝達物質誘導体 in vivo 放射性診断薬の開発に関する基礎研究

Synthesis of Radiohalogenated Diagnostic Agents

Regulation of Pharmacokinetics

Development of Radiopharmaceuticals for Diagnosis of Metabolic Function