Rchr
J-GLOBAL ID:200901047176303012   Update date: May. 27, 2020

Miyashita Akinori

ミヤシタ アキノリ | Miyashita Akinori
Affiliation and department:
Job title: Associate Professor
Homepage URL  (2): https://www.bri.niigata-u.ac.jp/field/genetics/index.htmlhttps://www.bri.niigata-u.ac.jp/en/field/genetics/index.html
Research field  (5): Neurology ,  Medical biochemistry ,  Genetics ,  Genomics ,  Neuroscience - general
Research keywords  (24): case-control study ,  human post-mortem brains ,  phase separation ,  RNA binding proteins ,  Stress granules ,  GWAS ,  association study ,  TREM2 ,  SORL1 ,  disease susceptibility genes ,  omics ,  transcriptome ,  FUS ,  APOE ,  microsatellite markers ,  single nucleotide variants ,  frontotemporal lobar degeneration ,  amyotrophic lateral sclerosis ,  Neurodegenerative disease ,  dementia ,  genome ,  Alzheimer's disease ,  SNP<sub>s</sub> ,  Microsatellite
Research theme for competitive and other funds  (11):
  • 2015 - 2018 Validation study on insulin resistance occuring in brain of Alzheimer disease
  • 2014 - 2016 Molecular analysis of the differentially expressed miRNA related to progression of Alzheimer's disease
  • 2013 - 2016 Copy number variation database of Alzheimer's disease for genome analysis
  • 2012 - 2015 Identification of target molecules related the progression of Alzheimer's disease
  • 2010 - 2015 Personal genome analysis on Alzheimer's disease
Show all
Papers (67):
  • Maria Yamasaki, Takashi Makino, Seik-Soon Khor, Hiromi Toyoda, Taku Miyagawa, Xiaoxi Liu, Hitoshi Kuwabara, Yukiko Kano, Takafumi Shimada, Toshiro Sugiyama, Hisami Nishida, Nagisa Sugaya, Mamoru Tochigi, Takeshi Otowa, Yuji Okazaki, Hisanobu Kaiya, Yoshiya Kawamura, Akinori Miyashita, Ryozo Kuwano, Kiyoto Kasai, Hisashi Tanii, Tsukasa Sasaki, Makoto Honda, Katsushi Tokunaga. Sensitivity to gene dosage and gene expression affects genes with copy number variants observed among neuropsychiatric diseases. BMC medical genomics. 2020. 13. 1. 55-55
  • Masataka Kikuchi, Michiko Sekiya, Norikazu Hara, Akinori Miyashita, Ryozo Kuwano, Takeshi Ikeuchi, Koichi M Iijima, Akihiro Nakaya. Disruption of a RAC1-centred network is associated with Alzheimer's disease pathology and causes age-dependent neurodegeneration. Human molecular genetics. 2020
  • Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan, Marina Cella, Tyler K Ulland, Konstantin Zaitsev, Akinori Miyashita, Takeshi Ikeuchi, Makoto Sainouchi, Akiyoshi Kakita, David A Bennett, Julie A Schneider, Michael R Nichols, Sean A Beausoleil, Jason D Ulrich, David M Holtzman, Maxim N Artyomov, Marco Colonna. Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease. Nature medicine. 2020. 26. 1. 131-142
  • Kikuchi M, Hara N, Hasegawa M, Miyashita A, Kuwano R, Ikeuchi T, Nakaya A. Enhancer variants associated with Alzheimer's disease affect gene expression via chromatin looping. BMC medical genomics. 2019. 12. 1. 128
  • Choi KY, Lee JJ, Gunasekaran TI, Kang S, Lee W, Jeong J, Lim HJ, Zhang X, Zhu C, Won SY, Choi YY, Seo EH, Lee SC, Gim J, Chung JY, Chong A, Byun MS, Seo S, Ko PW, Han JW, McLean C, Farrell J, Lunetta KL, Miyashita A, Hara N, Won S, Choi SM, Ha JM, Jeong JH, Kuwano R, Song MK, An SSA, Lee YM, Park KW, Lee HW, Choi SH, Rhee S, Song WK, Lee JS, Mayeux R, Haines JL, Pericak-Vance MA, Choo ILH, Nho K, Kim KW, Lee DY, Kim S, Kim BC, Kim H, Jun GR, Schellenberg GD, Ikeuchi T, Farrer LA, Lee KH, Neuroimaging Initative AD. APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample. Journal of clinical medicine. 2019. 8. 8
more...
MISC (128):
  • 樋口陽, 樋口陽, 春日健作, ZHU Bin, LIU Lixin, 石黒敬信, 石黒敬信, 徳武孝允, 宮下哲典, 小野寺理, 池内健. 血漿炎症系サイトカインと脳脊髄液バイオマーカーとの関連. Dementia Japan. 2019. 33. 4. 548
  • 朱斌, LIU Lixin, 三浦健, 樋口陽, 原範和, 月江珠緒, 今野卓哉, 春日健作, 宮下哲典, 池内健. ALSP患者において同定されたCSF1R変異の機能アッセイ. Dementia Japan. 2019. 33. 4. 548
  • 月江珠緒, 原範和, 宮下哲典, LIU Lixin, 樋口陽, ZHU Bin, 春日健作, 桑野良三, 桑野良三, 岩坪威, 池内健. SORL1レアバリアントとアルツハイマー病発症リスクとの遺伝的関連. Dementia Japan. 2019. 33. 4. 524
  • 宮下哲典, 原範和, 春日健作, LIU Lixin, 樋口陽, ZHU Bin, 月江珠緒, 石黒敬信, 村上涼太, 菊地正隆, 中谷明弘, 尾崎浩一, 新飯田俊平, 赤澤宏平, 桑野良三, 桑野良三, 岩坪威, 岩坪威, 池内健. 日本人におけるAPOEのコモン・レアバリアント解析. Dementia Japan. 2019. 33. 4. 519
  • 原範和, 宮下哲典, LIU Lixin, 樋口陽, 朱斌, 月江珠緒, 春日健作, 桑野良三, 岩坪威, 池内健. 日本人集団におけるABCA7機能喪失型変異とアルツハイマー病発症リスクとの関連. Dementia Japan. 2019. 33. 4. 547
more...
Education (3):
  • 1997 - 2000 Niigata University Graduate School, Division of National Science and Technology Doctoral program
  • 1995 - 1997 Niigata University Graduate School of Science and Technology Master’s program
  • 1991 - 1995 Niigata University Faculty of Science Department of Biology
Professional career (1):
  • PhD (Science) (Niigata University)
Work history (5):
  • 2018/04 - 現在 Niigata University Associate Professor
  • 2006/04 - 2018/03 Niigata University Assistant Professor
  • 2014/04 - 2017/03 University of Toronto Postdoctoral Research Fellow
  • 2002/04 - 2006/03 Niigata University Research Associate
  • 2000/04 - 2002/03 Niigata University Research Associate
Association Membership(s) (5):
The Japanese Society for Genome Editing ,  The Japan Society of Human Genetics ,  The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment ,  Japan Society for Dementia Research ,  The Molecular Biology Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page