Research theme for competitive and other funds (11):
2023 - 2024 複製開始タンパク質ORCのDNA認識機構の構造生物学的基盤
2022 - 2023 複製開始タンパク質ORCのDNA認識機構の構造生物学的基盤
2021 - 2022 ヒトORCのグアニン四重鎖結合と液液相分離の生理的意義
2021 - 2022 複製開始タンパク質ORCの構造とDNA結合に関する研究
2020 - 2021 ヒト複製開始タンパク質ORCのグアニン四重鎖DNA構造への結合に関する研究
2019 - 2020 ヒトORC1のグアニン四重鎖結合活性のDNA複製開始における役割
2015 - 2017 The roles of the G-quadruplex-binding activity of human ORC in replication origin establishment
2015 - Molecular mechanisms for establishment of the replication origins on human chromosomal DNA
2012 - 2014 Analysis of the structure and function of the RNA bound by human ORC
2012 - The potential involvement of RNA in the function at the metazoan replication origins
2009 - 2011 A novel role of RNA in the function at the replication origins in animal cells
Show all
Papers (33):
Afaf Eladl, Yudai Yamaoki, Keisuke Kamba, Shoko Hoshina, Haruka Horinouchi, Keiko Kondo, Shou Waga, Takashi Nagata, Masato Katahira. NMR characterization of the structure of the intrinsically disordered region of human origin recognition complex subunit 1, hORC1, and of its interaction with G-quadruplex DNAs. Biochemical and Biophysical Research Communications. 2023
Aina Maria Mas, Enrique Goñi, Igor Ruiz de los Mozos, Aida Arcas, Luisa Statello, Jovanna González, Lorea Blázquez, Wei Ting Chelsea Lee, Dipika Gupta, Álvaro Sejas, et al. ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins. Nature Communications. 2023. 14. 1
Afaf Eladl, Yudai Yamaoki, Shoko Hoshina, Haruka Horinouchi, Keiko Kondo, Shou Waga, Takashi Nagata, Masato Katahira. Investigation of the Interaction of Human Origin Recognition Complex Subunit 1 with G-Quadruplex DNAs of Human c-myc Promoter and Telomere Regions. International Journal of Molecular Sciences. 2021. 22. 7. 3481-3481