Research field (4)：
Hygiene and public health (laboratory)
, Environmental effects of chemicals
, Ecology and environmental science
, Pharmaceuticals - health and biochemistry
Research keywords (6)：
nephrotoxicity
, selenium
, manganese
, arsenic
, cadmium
, metal transporter
Research theme for competitive and other funds (34)：
2023 - 2026 Studies on the mechanisms of arsenic-induced vascular and muscular toxicity
2021 - 2025 Elucidation of the mechanisms of arsenic-induced cardiometabolic diseases
2019 - 2022 環境医学領域におけるメタロミクス手法の開発と応用に関する研究
2016 - 2020 Versatile health effects in Bangladesh residents exposed to ground water arsenic
2016 - 2019 Health and medical measures as well as investigations in Akita prefecture, the forgotten Japanese heaviest cadmium-polluted area
2014 - 2016 Identification of unknown form of arsenicals and evaluation of toxicity in freshwater fish
2012 - 2015 A study on the involvement of immune dysfunction in chronic arsenic poisoning
2012 - 2015 Studies on modifying factors for arsenic toxicity in arsenic-endemic areas in Asia
2011 - 2012 S100A8/A9 as a new mediator of arsenic toxicity
2010 - 2012 Effects of heavy metals on immunological functions
2007 - 2009 Studies on metal toxicology and transport using omics approaches
Kabir E, Shila TT, Islam J, Beauty SA, Islam F, Hossain S, Nikkon F, Himeno S, Hossain K, Saud ZA. Concomitant Exposure to Lower Doses of Arsenic, Lead, and Manganese Induces Greater Synergistic Neurotoxicity Than Individual Metals in Mice. Biological trace element research. 2024
Hiroki Taguchi, Daigo Sumi, Seiichiro Himeno, Hitomi Fujishiro. Ferroptosis is involved in cisplatin sensitivity of the S3 segment of immortalized proximal tubule cells. Toxicology. 2024. 153840-153840
Moriom Khatun, Nazmul Haque, Abu Eabrahim Siddique, Abdus S Wahed, Md Shofikul Islam, Shuchismita Khan, Ahsanul Mahbub Jubayar, Junayed Sadi, Ehsanul Kabir, Tasnim Tabassum Shila, et al. Arsenic Exposure-Related Hypertension in Bangladesh and Reduced Circulating Nitric Oxide Bioavailability. Environmental health perspectives. 2024. 132. 4. 47003-47003
Seiichiro Himeno. Effects of arsenic exposure on hypertension, atherosclerosis, and diabetes. 2023. 285. 2. 123-126
Moriom Khatun, Abu Eabrahim Siddique, Abdus S Wahed, Nazmul Haque, Selim Reza Tony, Jahidul Islam, Shahnur Alam, Md Khalequzzaman Sarker, Isabela Kabir, Shakhawoat Hossain, et al. Association between serum periostin levels and the severity of arsenic-induced skin lesions. PloS one. 2023. 18. 1. e0279893
上村歩, 田口央基, 松本可南子, 藤代瞳, 姫野誠一郎, 角大悟. Time-dependence of intracellular Pt accumulation and cytotoxicity by exposure to cisplatin. 日本薬学会年会要旨集(Web). 2024. 144th
竹川芽依, 田口央基, 藤代瞳, 姫野誠一郎, 姫野誠一郎, 角大悟. Inhibitory effect of arsenite on differentiation of mouse myoblast C2C12 cells. 日本薬学会年会要旨集(Web). 2024. 144th
竹川芽依, 田口央基, 藤代瞳, 姫野誠一郎, 角大悟. Inhibitory effect of arsenite on differentiation of mouse myoblast C2C12 cells. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
田口央基, 藤代瞳, 姫野誠一郎, 姫野誠一郎, 角大悟. Ferroptosis involved in the vulnerability of the proximal tubule S3 region to cisplatin. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
2022/07 - Pfizer Award Segment-specific and direction-dependent transport of cadmium and manganese in immortalized S1, S2, and S3 cells derived from mouse kidney proximal tubules
2018/04 - 食品農医薬品安全性評価センター 望月喜多司記念業績賞
2015/08 - メタルバイオサイエンス研究会 研究功労賞
2013/11 - ISTERH Investigation Award
Association Membership(s) (7)：
Science Council of Japan
, 日本ヒ素研究会
, 日本毒性学会
, 日本生化学会
, 日本微量元素学会
, 日本薬学会
, 日本衛生学会
