Hisaka Akihiro

ヒサカアキヒロ | Hisaka Akihiro

Affiliation and department：
Homepage URL (1)： https://www.p.chiba-u.jp/lab/cpp/index.html

Research field (1)： Clinical pharmacy

Research keywords (3)：臨床薬理学 , 薬物動態学 , Pharmacokinetics and Clinical Pharmacology

Research theme for competitive and other funds (14)：

2021 - 2024 Significance of ketone body metabolic shift in diabetes and long-term prognosis prediction
2017 - 2020 Model based meta-analysis and establishment of PBPK model for appropriate use of factor Xa inhibitor
2015 - 2019 Expression of precipitating factors of pruritus found in humans in an imiquimodinduced psoriasis mouse model
2015 - 2017 Epigenetic regulation shifted cellular metabolism of cancer cells, which contributed to potentiate drug sensitivity of antiangiogenic agents.
2013 - 2015 Development of Micro-blood-sampling Method for Pharmacokinetic Analysis in Clinical Studies

Show all

Papers (66)：

Hiromi Sato, Ayana Ishikawa, Hideki Yoshioka, Ryota Jin, Yamato Sano, Akihiro Hisaka. Model-based meta-analysis of HbA1c reduction across SGLT2 inhibitors using dose adjusted by urinary glucose excretion. Scientific Reports. 2024
Ryota Jin, Hideki Yoshioka, Hiromi Sato, Akihiro Hisaka. Data-driven disease progression model of Parkinson's disease and effect of sex and genetic variants. CPT: pharmacometrics & systems pharmacology. 2024. 13. 4. 649-659
Manisha Bhateria, Isha Taneja, Kajal Karsauliya, Ashish Kumar Sonker, Yukihiro Shibata, Hiromi Sato, Sheelendra Pratap Singh, Akihiro Hisaka. Predicting the in vivo developmental toxicity of fenarimol from in vitro toxicity data using PBTK modelling-facilitated reverse dosimetry approach. Toxicology and applied pharmacology. 2024. 484. 116879-116879
Yukako Soejima, Hideki Yoshioka, Sayuri Guro, Hiromi Sato, Hiroto Hatakeyama, Yasunori Sato, Yoshihide Fujimoto, Naohiko Anzai, Akihiro Hisaka. Exercise training outcomes in patients with chronic heart failure with reduced ejection fraction depend on patient background. Frontiers in cardiovascular medicine. 2024. 11. 1330235-1330235
Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Hiromi Sato, Akihiro Hisaka. Involvement of multiple cytochrome P450 isoenzymes in drug interactions between ritonavir and direct oral anticoagulants. Drug Metabolism and Pharmacokinetics. 2023. 53. 100498-100498

ｍore...

MISC (43)：

金森大誠, 宮崎菜摘, 青木重樹, 伊藤晃成, 樋坂章博, 畠山浩人. 熱ストレス下における熱耐性卵巣癌細胞の代謝シフトの解明. 日本薬学会関東支部大会講演要旨集. 2021. 65th (CD-ROM)
佐藤洋美, 副島呉竹, 副島呉竹, 樋坂章博. 薬物動態に影響する高齢者の生理学的変化と性差. 日本性差医学・医療学会学術集会プログラム・抄録集. 2021. 14th
爲本雄太, 柴田侑裕, 吉友葵, 佐藤洋美, 樋坂章博. Importance of systematic assessment of time-dependent inhibition of CYP isozymes: inhibition of CYP1A2 and CYP2C19 by fluvoxamine. 日本薬剤学会年会講演要旨集(CD-ROM). 2021. 36th
Hideki Yoshioka, Akihiro Hisaka, Yasunori Sato. Proposal of a New Risk Score for Hospital Death Due to Acute Coronary Syndrome Developed by Machine Learning. CIRCULATION RESEARCH. 2020. 127. 12. E281-E281
爲本雄太, 柴田侑裕, 保月静香, 佐藤洋美, 樋坂章博. 代謝寄与率(fm)の評価に与える緩衝液条件の影響:in vitroカクテル法による検討. 臨床薬理. 2020. 51. Supplement

ｍore...

Books (3)：

Education (2)：

Committee career (2)：

Association Membership(s) (8)：

国際薬物動態学会 , 日本ファーマコメトリクス研究会 , 日本TDM学会 , 日本臨床薬理学会 , 日本医療薬学会 , 日本薬剤学会 , 日本薬物動態学会 , 日本薬学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page